Avian Influenza Clinical Slides PDF

Made with Xodo PDF Reader and Editor Avian Influenza Clinical slides Avian influenza (AI) is a viral disease characterized by respiratory signs, depression and reduced feed and water intake. In egg laying birds there is a decline in egg production. ‫( ﻫﻲ ﻣﺮض ﻓﲑوﳼ ﻳﳣﲒ ﺑ...

Made with Xodo PDF Reader and Editor Avian Influenza Clinical slides Avian influenza (AI) is a viral disease characterized by respiratory signs, depression and reduced feed and water intake. In egg laying birds there is a decline in egg production. ‫( ﻫﻲ ﻣﺮض ﻓﲑوﳼ ﻳﳣﲒ ﺑﺄﻋﺮاض ﺗﻨﻔﺴﻴﺔ واﻛﺘﯫب واﻧﺨﻔﺎض اﺳﳤﻼك اﻟﻌﻠﻒ‬AI) ‫أﻧﻔﻠﻮﻧﺰا اﻟﻄﻴﻮر‬.‫ ﰲ اﻟﻄﻴﻮر اﻟﱵ ﺗﻀﻊ اﻟﺒﻴﺾ ﻫﻨﺎك اﻧﺨﻔﺎض ﰲ إﻧﺘﺎج اﻟﺒﻴﺾ‬.‫واﳌﺎء‬ Etiology Classification Family: Orthomyxoviridae Genus: Influenzavirus A. This genus has one species, influenza A virus. Species: influenza A virus. ‫؟‬H5N1 ‫ﻣﺎ ﻫﻲ ﺳﻼﻟﺔ إﻧﻔﻠﻮﻧﺰا اﻟﻄﻴﻮر‬ ‫ﻫﺬه ﺳﻼﻟﺔ ﻣﻦ ﻓﲑوس إﻧﻔﻠﻮﻧﺰا اﻟﻄﻴﻮر ﺷﺪﻳﺪة اﻟﻌﺪوى ﺑﲔ اﻟﻄﻴﻮر وﻟﻬﺎ ﺧﻄﺮ‬.‫ﻣﻨﺨﻔﺾ ﻟﻺﺻﺎﺑﺔ ﺑﺎﻷﻣﺮاض ﺑﲔ اﻟﺒﴩ‬  Made with Xodo PDF Reader and Editor ‫ﻏﺎﻟﺒﺎ ﻣﺎ ﺗﻜﻮن اﻟﻌﻼﻣﺔ‬ ً HPAI ‫اﻷوﱃ ﻟﻔﲑوس‬ ‫ﰲ اﻟﺪﺟﺎج أو اﻟﺪﻳﻚ‬ ‫اﻟﺮوﻣﻲ ﻫﻲ اﻟﺒﺪاﻳﺔ‬ ‫اﳌﻔﺎﺟﺌﺔ ﻻرﺗﻔﺎع ﻣﻌﺪل‬.‫ﻧﻔﻮق اﻟﻘﻄﻴﻊ‬ Often the first sign of HPAI virus in chicken or turkey is the sudden onset of high flock mortality.  Made with Xodo PDF Reader and Editor ‫ﺗﻈﻬﺮ اﻵﻓﺎت ﺑﺸﻜﻞ ﺷﺎﺋﻊ ﰲ اﻟﺠﻬﺎز‬ ‫ ﺗﺼﺒﺢ اﻟﺒﻄﺎﻧﺎت اﳌﺨﺎﻃﻴﺔ‬.‫اﻟﺘﻨﻔﴘ‬ ‫ﻟﻠﺠﻴﻮب اﻷﻧﻔﻴﺔ واﻟﻘﺼﺒﺔ اﻟﻬﻮاﺋﻴﺔ‬ ‫ وﰲ ﺑﻌﺾ‬،‫ﻣﺘﻮرﻣﺔ واﻟﳤﺎﺑﻴﺔ‬ ‫اﻷﺣﻴﺎن ﻗﺪ ﻳﺤﺪث اﺣﺘﻘﺎن أو ﻧ ﻳﻒ‬.‫ﰲ اﻟﻐﺸﺎء اﳌﺨﺎﻃﻲ ﻟﻠﺮﻏﺎﻣﻰ‬ lesions are commonly seen in the respiratory system. The mucosal linings of the sinuses and the trachea become edematous and inflammatory and sometimes there may be congestion or hemorrhage in the tracheal mucosa. Multifocal necrosis and hemorrhage of comb and wattles, H5N2 HPAI virus.  Made with Xodo PDF Reader and Editor ‫وذﻣﺔ ﺷﺪﻳﺪة ﰲ اﳌﺸﻂ‬ ‫واﻟﺪﻻﻳﺎت ﻣﻊ وذﻣﺔ ﺣﻮل‬ ‫اﻟﺤﺠﺎج وﻧﺨﺮ ﰲ اﻟﺒﴩة‬ ‫ ﻓﲑوس‬،‫ﻋﻨﺪ ﻗﺎﻋﺪة اﳌﺸﻂ‬.H5N2 HPAI Severe edema of comb and wattles with accompanying periorbital edema and necrosis of epidermis at base of the comb, H5N2 HPAI virus.  Made with Xodo PDF Reader and Editor HPAI virus (Chicken). Sub-cutaneous necrosis of the foot pad ‫ﻧﺨﺮ ﺗﺤﺖ اﻟﺠﻠﺪ ﰲ وﺳﺎدة اﻟﻘﺪم‬  Made with Xodo PDF Reader and Editor hemorrhage: escape of RBS for B.V ‫ﻧ ﻳﻒ ﺣﺎد ﺗﺤﺖ‬ ،‫اﻟﺠﻠﺪ ﰲ اﻟﻘﺪﻣﲔ‬ ‫دﺟﺎج ﻋ ه ﺛﻼﺛﺔ‬ ‫أﺳﺎﺑﻴﻊ‬ Severe subcutaneous hemorrhages of feet, three-week- old chicken, intranasal exposure to A/Hong Kong/156/1997 (H5N1). Made with Xodo PDF Reader and Editor ‫ﻳﺘﻐﲑ ﻟﻮن اﻷﻧﺴﺠﺔ ﺗﺤﺖ اﻟﺠﻠﺪ ﰲ أﺳﻔﻞ اﻟﺴﺎﻗﲔ واﻟﻘﺪﻣﲔ‬ ‫ﻣﻦ ﺧﻼل ﺑﺆر ﻣﺘﻔﺎوﺗﺔ اﻟﺤﺠﻢ وﻣﺘﺠﻤﻌﺔ ذات ﻟﻮن أﺣ إﱃ‬.‫ اﻟﻄﺮف ﺑﺄﻛﻤﻠﻪ ﻣﻨﺘﻔﺦ‬.‫أرﺟﻮاﱐ‬ The subcutaneous tissues of the lower legs and feet are discolored by variably sized, coalescing, red to purple foci. The entire limb is swollen.  Made with Xodo PDF Reader and Editor ‫ ﻋﲆ اﻷﺟﺰاء ﻏﲑ‬.‫ﺗﺆدي اﻟﻮذﻣﺔ ﺗﺤﺖ اﻟﺠﻠﺪ إﱃ ﺗﻮرم اﻟﺮأس واﻟﻮﺟﻪ واﻟﺮﻗﺒﺔ واﻟﻘﺪﻣﲔ ﺑﺎﻹﺿﺎﻓﺔ إﱃ ﻧ ﻳﻒ ﳕﺸﺎت إﱃ ﻛﺪﻣﺎت‬.‫ ﻗﺪ ﺗﻜﻮن ﻫﻨﺎك ﺑﺆر ﻧﺨ ﻳﺔ وﻧ ﻳﻒ وزرﻗﺔ‬،‫ ﺧﺎﺻﺔ اﳌﺸﻂ واﻟﺪﻻﻳﻞ‬،‫اﳌﺼﻘﻮﻟﺔ ﻣﻦ اﻟﺠﻠﺪ‬ A subcutaneous edema results in swelling of the head, face, neck and feet along with petechial-to-ecchymotic hemorrhages. On the non- feathered parts of the skin, especially the comb and wattles, there may be necrotic foci, hemorrhage, and cyanosis.  Made with Xodo PDF Reader and Editor congested:engog ment in B.V ‫ أﻳﺎم ﻣﻦ‬3 ‫ﰎ اﻟﺘﻘﺎط ﻫﺬه اﻟﺼﻮرة ﺑﻌﺪ‬ ‫اﻟﺘﻠﻘﻴﺢ اﻟﺘﺠ ﻳﱯ ﻷﻧﻔﻠﻮﻧﺰا اﻟﻄﻴﻮر ﺷﺪﻳﺪة‬ ‫ اﳌﻠﺘﺤﻤﺔ ﻣﺤﺘﻘﻨﺔ وﻫﻨﺎك‬.‫اﻹﻣﺮاض‬.‫آﻓﺎت ﻧﺰﻓﻴﺔ ﻋﲆ اﻷﻏﺸﻴﺔ اﳌﺨﺎﻃﻴﺔ‬ This image was taken 3 days post experimental inoculation with highly pathogenic avian influenza. The conjunctivae are congested and there are hemorrhagic lesions on the mucous membranes.  Made with Xodo PDF Reader and Editor the airways leading to asphyxiation of the bird. Airsacculitis ‫ اﻟﳤﺎب اﻟﺤﻮﻳﺼﻼت اﻟﻬﻮاﺋﻴﺔ‬.‫اﻟﺸﻌﺐ اﻟﻬﻮاﺋﻴﺔ ﻣﻤﺎ ﻳﺆدي إﱃ اﺧﺘﻨﺎق اﻟﻄﺎﺋﺮ‬ LPAI virus (Turkey). Sinusitis. sinustitis: information of sinus  Made with Xodo PDF Reader and Editor ‫ﺗﻜﻮن اﻷوﻋﻴﺔ اﻟﺪﻣﻮﻳﺔ اﳌﻮﺟﻮدة‬ ‫ﻋﲆ اﻟﺴﻄﺢ اﻟﱪاﱐ ﻟﻠﻘﺼﺒﺔ‬ ‫ ﻣﻦ‬.‫اﻟﻬﻮاﺋﻴﺔ ﻣﺤﺘﻘﻨﺔ وﺑﺎرزة‬ ‫اﻟﻮاﺿﺢ أﳖﺎ ﺗﻌﻤﻞ ﺑﺎﻟﺘﻮازي ﻣﻊ‬ ‫ اﻟﻘﺼﺒﺔ‬.‫ﺣﻠﻘﺎت اﻟﻘﺼﺒﺔ اﻟﻬﻮاﺋﻴﺔ‬ ‫اﻟﻬﻮاﺋﻴﺔ ﺣ اء ﻣﻨﺘﴩة وﳝﻜﻦ‬ ‫رؤﻳﺔ ﺑﺆر ﻏﲑ ﻣﻨﺘﻈﻤﺔ ﻣﻦ اﻷﺣ‬ ‫إﱃ اﻷرﺟﻮاﱐ ﰲ ﺟﻤﻴﻊ أﻧﺤﺎء‬.‫ﺟﺪار اﻟﻘﺼﺒﺔ اﻟﻬﻮاﺋﻴﺔ‬ The blood vessels on the adventitial surface of the trachea are congested and prominent. They are evident running parallel to the tracheal rings. The trachea is diffusely red and irregular red to purple foci can be seen throughout the tracheal wall.  Made with Xodo PDF Reader and Editor This is a closed segment of trachea with larynx (right side of image). The dark red mucosa can be seen through the adventitia of the trachea and the dark color of the proximal trachea suggests the presence of luminal exudate.` ‫ ﳝﻜﻦ رؤﻳﺔ اﻟﻐﺸﺎء‬.(‫ﻫﺬا ﺟﺰء ﻣﻐﻠﻖ ﻣﻦ اﻟﻘﺼﺒﺔ اﻟﻬﻮاﺋﻴﺔ ﻣﻊ اﻟﺤﻨﺠﺮة )اﻟﺠﺎﻧﺐ اﻷﳝﻦ ﻣﻦ اﻟﺼﻮرة‬ ‫ وﻳﺸﲑ اﻟﻠﻮن اﻟﺪاﻛﻦ ﻟﻠﻘﺼﺒﺔ اﻟﻬﻮاﺋﻴﺔ‬،‫اﳌﺨﺎﻃﻲ اﻷﺣ اﻟﺪاﻛﻦ ﻣﻦ ﺧﻼل ﻏﻼﻓﺔ اﻟﻘﺼﺒﺔ اﻟﻬﻮاﺋﻴﺔ‬.‫اﻟﻘ ﻳﺒﺔ إﱃ وﺟﻮد اﻹﻓﺮازات اﻟﻠﻤﻌﻴﺔ‬  Made with Xodo PDF Reader and Editor antitosife:treatment of edama ‫اﻟﺪاﻛﻦ ﻟﻠﻐﺸﺎء اﳌﺨﺎﻃﻲ‬ ‫ﰎ ﻓﺘﺢ اﻟﻘﺼﺒﺔ اﻟﻬﻮاﺋﻴﺔ ﻟﻴﻜﺸﻒ اﻟﻠﻮن اﻷﺣ‬ The trachea has been opened to reveal the dark red color to the mucosa Made with Xodo PDF Reader and Editor adventist: cover the organ and conecte between them ‫ ﺗﻜﻮن اﻟﺤﻤﺔ اﻟﺮﯮﻳﺔ‬.‫ﻫﻨﺎك ﻋﺪة ﺑﺆر ﺣ اء ﻏﲑ ﻣﻨﺘﻈﻤﺔ اﻟﺸﻜﻞ ﰲ اﻟﺮﺋﺘﲔ‬ ‫ اﻷوﻋﻴﺔ اﻟﺪﻣﻮﻳﺔ‬.‫ﺑﺄﻛﻤﻠﻬﺎ ﻣﺒﻠﻠﺔ وﻻﻣﻌﺔ ﻣﻊ وﺟﻮد ﺑﻌﺾ اﳌﻨﺎﻃﻖ اﳌﺤ ّ ة‬.‫ﺑﺎرزة‬ There are several, irregularly shaped red foci in the lungs. The entire pulmonary parenchyma is wet and glistening with some areas of reddening. The blood vessels are prominent.  Made with Xodo PDF Reader and Editor Proventricular hemorrhages.  Made with Xodo PDF Reader and Editor ‫ﻧ ﻳﻒ ﻧﺒﱵ ﻣﺨﺎﻃﻲ ﻣﺤﻴﻂ ﺑﺎﻟﻐﺪد اﻟﺒﻄﻴﻨﻴﺔ دﺟﺎج‬ /‫ﻫﻮﻧﺞ ﻛﻮﻧﺞ‬/‫ﻋ ﺛﻼﺛﺔ أﺳﺎﺑﻴﻊ اﻟﺘﻌﺮض اﻟﻮ ﻳﺪي أ‬ 156/1997 Mucosal petechial hemorrhages surrounding proven- tricular glands, three-week-old chicken, intravenous exposure to A/ Hong Kong/156/1997  Made with Xodo PDF Reader and Editor serosa:covering the organ only like serosa intestine necrosis and hemorrhage in Peyer’s patches, proventriculus and epicardium..‫ اﻟﱪوﻓﻨﺘ ﻳﻜﻮﻟﺲ واﻟﻨﺨﺎب‬،‫ﻧﺨﺮ وﻧ ﻳﻒ ﰲ ﺑﻘﻊ ﺑﺎﻳﺮ‬ HPAI virus H5N2 (Mexico, 1994) Necrosis or hemor- rhage in the mucosa of the proventriculus.  Made with Xodo PDF Reader and Editor.‫أﻃﺮاف اﻟﻐﺪد اﻟﺒﻄﻴﻨﻴﺔ ﺣ اء زاﻫﻴﺔ‬ The tips of the proventricular glands are bright red.  Made with Xodo PDF Reader and Editor ‫ﻧ ﻳﻒ ﰲ اﻷﻧﺴﺠﺔ اﻟﻠﻤﻔﺎوﻳﺔ ﻟﺒﻘﻊ ﺑﺎﻳﺮ ورﺗﺞ‬ ،‫ دﺟﺎج ﻋ ه ﺛﻼﺛﺔ أﺳﺎﺑﻴﻊ‬،‫ﻣﻴﻜﻞ ﻟﻠﺼﺎﰂ‬ ‫اﻟﺘﻌﺮض ﻋﻦ ﻃ ﻳﻖ اﻟﻮ ﻳﺪ ﻟﻔﲑوس‬ Hemorrhage in lymphoid tissue of Peyer's patches and Meckel's diverticulum of the jejunum, three-week-old chicken, intravenous exposure to A/chicken/Hong Kong/27402/1997 (H5N1) HPAI virus, 1 DPI.  Made with Xodo PDF Reader and Editor ‫ﻧ ﻳﻒ ﳕﴚ ﰲ اﻟﺪﻫﻮن اﻟﻨﺨﺎﺑﻴﺔ‬ Petechial hemorrhages in epicardial fat, H5N2 HPAI virus, 4 DPI. Made with Xodo PDF Reader and Editor ‫ﺗﺤﺘﻮي اﻟﺪﻫﻮن اﻟﻨﺨﺎﺑﻴﺔ ﻋﲆ ﻋﺪد ﻛﺒﲑ ﻣﻦ اﻟﺒﺆر‬ ‫اﻟﺤ اء اﻟﺰاﻫﻴﺔ واﳌﺤﺪدة واﳌﻠﺘﺤﻤﺔ ﰲ ﺑﻌﺾ‬ ‫اﻷﺣﻴﺎن‬ The epicardial fat contains a large number of bright red, pinpoint, sometime coalescing red foci.  Made with Xodo PDF Reader and Editor ‫ﻳﱲ ﺗﻨﻘﻴﻂ اﻷﺳﻄﺢ اﳌﺼﻠﻴﺔ ﻟﻠﺤﻠﻘﺎت اﳌﻌﻮﻳﺔ‬ ‫واﻟﺪﻫﻮن اﳌﺴﺎ ﻳﻘﻴﺔ ﺑﻮاﺳﻄﺔ ﺑﺆر ﺣ اء ﻋﺪﻳﺪة‬ ‫ أﺟﺰاء ﻣﻦ اﻷﻣﻌﺎء اﳌﻮﺟﻮدة ﻋﲆ‬.‫وﻣﺤﺪدة‬ ‫اﻟﺠﺎﻧﺐ اﻷﻳﴪ ﻣﻦ اﻟﺼﻮرة ﻣﻐﻄﺎة ﺑﺨﻴﻮط ﻣﻦ‬.‫ﻣﺎدة ﺻﻔﺮاء ﻗﺎﺑﻠﺔ ﻟﻠﺘﻔﺘﻴﺖ‬ The serosal surfaces of the intestinal loops and the mesenteric fat are stippled by numerous, pinpoint red foci. Portions of the intestines on the left-hand side of the picture are coated by strands of yellow, friable material.  Made with Xodo PDF Reader and Editor ‫ﺗﺘﻘﻠﺺ اﻟﻌﺪﻳﺪ ﻣﻦ ﺑﺼﻴﻼت‬ ‫ ﺗﻜﻮن إﺣﺪى‬.‫اﳌﺒﻴﺾ وﺗﺮﺗﴠ‬ ‫اﻟﺒﺼﻴﻼت ذات ﻟﻮن أﺧﴬ داﻛﻦ‬ ‫وﺑﻌ ﺎ ﻳﺤﺘﻮي ﻋﲆ ﻣﻨﺎﻃﻖ‬.‫ﺣ اء‬ Several of the ovarian follicles are shrunken and flaccid. One of the follicles is dark green and some contain red areas.  Made with Xodo PDF Reader and Editor Egg yolk peritonitis in a LPAI positive laying hen.  Made with Xodo PDF Reader and Editor Control Management Procedures Standard control measures for any AI outbreak include:- 1. Quarantine of the infected flocks and usually a quarantine zone.‫اﻟﺤﺠﺮ اﻟﺼﺤﻲ ﻟﻠﻘﻄﻌﺎن اﳌﺼﺎﺑﺔ وﻋﺎدة ﻣﺎ ﻳﱲ إﻧﺸﺎء ﻣﻨﻄﻘﺔ ﺣﺠﺮ ﺻﺤﻲ ﺣﻮل اﻟﻘﻄﻌﺎن اﳌﺼﺎﺑﺔ‬ around the infected flocks. 2. Increased biosecurity by greatly restricting access of personnel and ‫ﻳﺎدة اﻷﻣﻦ اﻟﺒﻴﻮﻟﻮﺟﻲ ﻣﻦ ﺧﻼل ﺗﻘﻴﻴﺪ وﺻﻮل اﻷﻓﺮاد واﳌﻌﺪات إﱃ اﳌﺰا ع اﳌﻮﺟﻮدة ﰲ ﻣﻨﻄﻘﺔ اﻟﺤﺠﺮ‬ equipment ‫اﻟﺼﺤﻲ وإﻟﳱﺎ ﺑﺸﻜﻞ ﻛﺒﲑ‬ to and from farms in the quarantine zone. 3. Increased surveillance on surrounding farms to monitor for evidence of spread.‫ﻳﺎدة اﳌﺮاﻗﺒﺔ ﻋﲆ اﳌﺰا ع اﳌﺤﻴﻄﺔ ﻟﺮﺻﺪ اﻷدﻟﺔ ﻋﲆ اﻧﺘﺸﺎر ﻋﺪوى اﻷﻧﻔﻠﻮﻧﺰا‬ of influenza infections. 4. For outbreaks of HPAI, infected flocks are depopulated, often with disposal of ‫وﻏﺎﻟﺒﺎ ﻣﺎ ﻳﱲ اﻟﺘﺨﻠﺺ ﻣﻦ اﻟﻄﻴﻮر‬ ً ،‫ ﻳﱲ إﺧﻼء اﻟﻘﻄﻌﺎن اﳌﺼﺎﺑﺔ‬،‫ﻋﻨﺪ ﺗﻔﴚ ﻣﺮض أﻧﻔﻠﻮﻧﺰا اﻟﻄﻴﻮر ﻋﺎﻟﻴﺔ اﻹﻣﺮاض‬.‫ﻋﻦ ﻃ ﻳﻖ اﻟﺤﺮق أو اﻟﺪﻓﻦ ﰲ اﳌﺰرﻋﺔ‬ the birds by burning or burial on the farm.  Made with Xodo PDF Reader and Editor Vaccination Vaccines - Immunity is hemagglutinin subtype specific. Because birds are susceptible to all 16 hemagglutinins, preventive vaccination is not practical. Treatment There is no effective treatment. However, good husbandry may reduce losses from secondary infections ‫ﻧﻈﺮا ﻷن اﻟﻄﻴﻮر ﻣﻌﺮﺿﺔ ﻟﺠﻤﻴﻊ ﺑﺮوﺗﻴﻨﺎت‬ ً.‫ اﳌﻨﺎﻋﺔ ﻫﻲ ﻧﻮع ﻓﺮﻋﻲ ﻣﺤﺪد ﻣﻦ اﻟﺮاﺻﺔ اﻟﺪﻣﻮﻳﺔ‬- ‫ﻟﻘﺎﺣﺎت اﻟﺘﻄﻌﲓ‬ ‫ ﻓﺈن اﻟﺘ ﺑﻴﺔ‬،‫ وﻣﻊ ذﻟﻚ‬.‫ اﻟﻌﻼج ﻻ ﻳﻮﺟﺪ ﻋﻼج ﻓﻌﺎل‬.‫ﻋﻤﻠﻴﺎ‬ ً ‫ ﻓﺈن اﻟﺘﻄﻌﲓ اﻟﻮﻗﺎﰄ ﻟﻴﺲ‬،‫اﻟﻬﳰﺎﺟﻠﻮﺗﻴﻨﲔ اﻟﺴﺘﺔ ﻋﴩ‬ ‫اﻟﺠﻴﺪة ﻗﺪ ﺗﻘﻠﻞ ﻣﻦ اﻟﺨﺴﺎﺋﺮ اﻟﻨﺎﺟﻤﺔ ﻋﻦ اﻟﻌﺪوى اﻟﺜﺎﻧﻮﻳﺔ‬