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## X6 ### HTN **Adrenergics** 5 subcategories, only seen 3 * **Alpha 1 receptor blockers** (Peripheral) = ↓BP * **L-zosin** * **Beta receptor blockers** (peripheral) = ↓HR * **P-LOL** * ↓Secretion of renin * Long term use = ↓PVR * **Combination alpha 1 and beta receptor blo...

## X6 ### HTN **Adrenergics** 5 subcategories, only seen 3 * **Alpha 1 receptor blockers** (Peripheral) = ↓BP * **L-zosin** * **Beta receptor blockers** (peripheral) = ↓HR * **P-LOL** * ↓Secretion of renin * Long term use = ↓PVR * **Combination alpha 1 and beta receptor blockers** (Peripheral = ↓HR and vasodilation) * Example: **Abetalol** * **Adverse effects:** orthostatic hypotension and down symptoms ## ACE Inhibitors = ↓BP * **PRIL** * Prevents RAAS, ↓SVR via vasodilation * Prevents bradykinin breakdown (vasodilator) * So now we have more = ↓BP * **Renal protective effects** * **HIN** * **HF** prevents secretion of aldosterone allowing dialysis, which workload of heart * After MI, heart hypertrophy (thickening) of wall * This inhibition we relax blood vessels, reducing strain of * **Diabetes:** When at risk for diabetic nephropathy * ↓Glomerular pressure and proteinuria = preventing further damage. * **Adverse effects:** Dry, non-productive cough & hyperkalemia