Spermatogenesis Process

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40 Questions

Where does sperm production occur in the testicles?

Seminiferous tubules

What is the function of Leydig cells in the testicles?

Secreting testosterone

How many pyramidal compartments or testicular lobules divide the testis?


What is the main function of the tunica albuginea surrounding the testis?

Providing a dense connective tissue capsule

Where do the testes develop embryonically before moving to the scrotal sac?

Dorsal wall of the embryonic abdominal cavity

What is the first part of sperm production that involves mainly mitosis and meiosis?


Which type of spermatogonia acts as stem cells, dividing infrequently and giving rise to more rapidly dividing cells?

Type A spermatogonia

What are the cells with partially condensed chromosomes in various stages of synapsis and recombination during the first meiotic prophase known as?

Primary spermatocytes

Which phase of meiosis involves homologous chromosomes separating and producing secondary spermatocytes?

First meiotic division

What is the result of the second meiotic division in spermatogenesis?

Haploid cells

What allows free cytoplasmic communication among male germ cells during mitotic and meiotic divisions?

Intercellular bridges of cytoplasm

What is the function of the pampiniform venous plexus surrounding the testicular artery?

Cooling the arterial blood

What triggers testosterone synthesis in interstitial cells?

Luteinizing hormone (LH)

During which stage of development do fetal interstitial cells produce testosterone?

Third and fourth months of pregnancy

Where does sperm production mainly occur?

Seminiferous tubules

What type of cells physically and metabolically support developing sperm cell precursors?

Sertoli cells

Which hormone promotes the development of secondary male sex characteristics?


During spermiogenesis, what happens to the cytoplasm of spermatids?

It is shed as residual bodies

What is the role of type A spermatogonia in sperm production?

Acting as stem cells and progenitor cells

What is the significance of the intercellular bridges during spermatogenesis?

They help coordinate cell progress and communication

Where do haploid spermatids develop into spermatozoa?

Near the lumen of the seminiferous tubules

What happens to the cytoplasmic bridges during spermatid differentiation?

They are lost as spermatids differentiate

What do the interconnections among spermatogenic cells help achieve?

Coordinate cell divisions and differentiation

What is the process that involves dissolving the zona pellucida and dissociating cells of the corona radiata?

Acrosomal reaction

What is the main function of Sertoli cells in the testes?

Providing metabolic support to spermatogenic cells

What is the role of protamines in the sperm nuclei?

Replacing histones for highly condensed nuclei

Which organelle aggregates around the flagellum proximally to form the thickened middle piece in sperm development?


What is the main function of tight occluding junctions in Sertoli cells?

Forming a blood-testis barrier

What structure remains embedded in the Sertoli cell during the acrosome phase of sperm development?

Head of developing sperm

What are the three general functions of Sertoli cells in establishing the blood-testis barrier?

Support, protection, and nutrition

What is the function of transferrin in relation to Sertoli cells?

Transporting iron into the lumen for spermatogenic cell development

Which hormone promotes the production of nutrients and androgen-binding protein (ABP) by Sertoli cells?

Follicle-stimulating hormone (FSH)

What is the role of inhibin secreted by Sertoli cells?

Feeds back on the anterior pituitary gland to suppress FSH synthesis

What is the function of müllerian-inhibiting substance (MIS) secreted by Sertoli cells in the fetus?

Causes regression of the embryonic müllerian ducts

What happens to excess cytoplasm shed as residual bodies during spermiogenesis?

Phagocytosed and digested by Sertoli cell lysosomes

'Which of the following is NOT a function of Sertoli cells?'

Production of testosterone for spermiogenesis

What hormone does inhibin feed back on?

FSH synthesis and release

What is the role of transferrin in relation to Sertoli cells?

Transporting iron into the lumen for cell growth

What is a primary function of müllerian-inhibiting substance (MIS) secreted by Sertoli cells?

Causing regression of embryonic müllerian ducts

What is one of the functions of exocrine secretion by Sertoli cells?

Releasing water carrying sperm out of the testis

Test your knowledge on the process of spermatogenesis, from the stem cells to the formation of mature spermatozoa. Learn about the different stages such as mitosis, meiotic divisions, and spermiogenesis.

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