chapter 8

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20 Questions

What type of genome does HIV have?

Single-stranded RNA

Why does drug therapy with a single drug usually fail with HIV?

HIV mutates rapidly, leading to drug resistance.

What is the role of helper T cells in the immune system?

Regulate the immune response

Why are some people resistant to HIV infection?

They have a mutation in the CCR5 gene.

What is reverse transcriptase and why is the RT of HIV considered 'sloppy'?

It synthesizes DNA from an RNA template, prone to errors.

Where did SARS-CoV-2 most likely come from?

Bats

HIV stands for Human Influenza Virus.

False

HIV specifically targets B cells in the immune system.

False

CD4 is a surface target protein for SARS-CoV-2.

False

SARS-CoV-2 primarily invades the mitochondria of host cells.

False

There are multiple strains of SARS-CoV-2 that coexist without one replacing the other.

False

Only one type of vaccine has been developed against SARS-CoV-2.

False

Pharmacological methods are used to control and prevent SARS-CoV-2 infection.

True

Why does drug therapy with a single drug usually fail with HIV?

HIV has a high mutation rate, leading to the development of drug resistance.

What is the role of CCR5 in HIV infection?

CCR5 is a receptor on CD4 cells that HIV uses to enter and infect these cells.

Why are some people resistant to HIV infection?

They have a mutation in the CCR5 gene that prevents HIV entry into cells.

What is the main reason for the failure of the immune system after HIV infection?

HIV infects and kills helper T cells, weakening the immune response.

What is D32 related to in the context of HIV infection?

D32 is a region on the HIV genome responsible for drug resistance.

Why is reverse transcriptase in HIV considered 'sloppy'?

Reverse transcriptase has low fidelity, leading to frequent mutations in the viral genome.

What kind of virus is SARS-CoV-2?

SARS-CoV-2 is a coronavirus that causes respiratory infections.

Test your knowledge about HIV and AIDS with this quiz covering topics such as the virus, its effects on the immune system, transmission, and more.

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