Questions and Answers
What is the main function of zona pellucida in fertilization?
Act as a container for early development
Where does fertilization mostly occur?
Fallopian tube
What is the outcome of rapid synchronized cell division without growth in zygote development?
Cleavage to give morula
What is the characteristic of cells at the morula stage?
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What is the main function of the blastocyst?
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What is the significance of pre-implantation genetic screening in IVF clinics?
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What is the primary source of meiotic errors in embryos?
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What is the consequence of leaky mitotic cell cycle checkpoints in embryos?
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Study Notes
Zona Pellucida in Fertilization
- The main function of zona pellucida is to facilitate fertilization by allowing only one sperm to penetrate the egg while preventing polyspermy.
Site of Fertilization
- Fertilization mostly occurs in the ampulla of the fallopian tube.
Zygote Development
- Rapid synchronized cell division without growth in the zygote leads to the formation of blastomeres without an increase in size.
Morula Stage
- At the morula stage, cells are compacted, with minimal intercellular space, and are held together by tight junctions.
Blastocyst Function
- The main function of the blastocyst is to establish a dialogue between the embryonic and maternal tissues, preparing for implantation.
Pre-implantation Genetic Screening
- Pre-implantation genetic screening in IVF clinics allows for the selection of chromosomally normal embryos, reducing the risk of miscarriage and chromosomal abnormalities.
Meiotic Errors
- The primary source of meiotic errors in embryos is the failure of chromosomes to segregate properly during meiosis, leading to aneuploidy.
Mitotic Cell Cycle Checkpoints
- Leaky mitotic cell cycle checkpoints in embryos can lead to abnormal cell division, resulting in aneuploidy, miscarriage, or birth defects.
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Description
Test your knowledge of human development stages with this quiz. From fertilization to the formation of the morula, challenge yourself to remember the key events and processes involved in the early development of a human embryo.