10 Questions
The direct reversal DNA repair mechanism involves the use of a template to repair DNA damage.
False
Photoreactivation is a direct reversal DNA repair mechanism that can reverse the formation of pyrimidine dimers induced by UV light.
True
Methylation of guanine bases results in a DNA structure complimentary to cytosine.
False
Photo reactivating enzyme requires the presence of light for its repair function.
True
Direct reversal through methylation can reverse the alkylation of guanine at O6 position.
True
Photo reactivation through destruction of abnormal covalent bonds occurs in humans.
False
Direct reversal DNA repair mechanism is mainly classified into photoreactivation and methylation.
True
The direct reversal mechanism involves replacing damaged nucleotide bases.
False
Methyl guanine methyl transferase (MGMT) restores the original guanine by transferring the methylation product to its active site.
True
Direct reversal mechanisms are not impacted by environmental factors.
False
Test your knowledge on Sickle Cell Anemia, point mutations, frameshift mutations, and the effects on the B-globin chain of Hemoglobin. Understand how a mutation like changing codon GAG to GUG at the 6th position can cause significant changes in protein synthesis.
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