Cytogenetics & Frameshift Mutation Quiz

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10 Questions

The direct reversal DNA repair mechanism involves the use of a template to repair DNA damage.

False

Photoreactivation is a direct reversal DNA repair mechanism that can reverse the formation of pyrimidine dimers induced by UV light.

True

Methylation of guanine bases results in a DNA structure complimentary to cytosine.

False

Photo reactivating enzyme requires the presence of light for its repair function.

True

Direct reversal through methylation can reverse the alkylation of guanine at O6 position.

True

Photo reactivation through destruction of abnormal covalent bonds occurs in humans.

False

Direct reversal DNA repair mechanism is mainly classified into photoreactivation and methylation.

True

The direct reversal mechanism involves replacing damaged nucleotide bases.

False

Methyl guanine methyl transferase (MGMT) restores the original guanine by transferring the methylation product to its active site.

True

Direct reversal mechanisms are not impacted by environmental factors.

False

Test your knowledge on Sickle Cell Anemia, point mutations, frameshift mutations, and the effects on the B-globin chain of Hemoglobin. Understand how a mutation like changing codon GAG to GUG at the 6th position can cause significant changes in protein synthesis.

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