Which substrate is NOT a precursor for gluconeogenesis? A) Amino acids B) Fatty acids C) Glycerol D) Lactate
Understand the Problem
The question is asking to identify which of the given substrates (amino acids, fatty acids, glycerol, lactate) is not involved in the process of gluconeogenesis, which is the synthesis of glucose from non-carbohydrate precursors.
Answer
Fatty acids
The final answer is fatty acids.
Answer for screen readers
The final answer is fatty acids.
More Information
Fatty acids are broken down into acetyl CoA. They cannot be converted into glucose via gluconeogenesis.
Tips
A common mistake is to include all fatty acids without considering odd-chain fatty acids which can contribute via propionate conversion.
Sources
- Physiology, Gluconeogenesis - StatPearls - NCBI Bookshelf - ncbi.nlm.nih.gov
- Gluconeogenesis - an overview | ScienceDirect Topics - sciencedirect.com
- Count the carbons in acetyl CoA and pyruvic acid - Vaia - vaia.com
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