Which of the following would not contribute to the cytoskeleton that underpins gross neuronal shape: A. MAP-2, B. Tau, C. Microtubules, D. Actin, E. Synaptotagmin?

Understand the Problem

The question is asking for information about the roles of specific molecules in relation to the cytoskeleton of neurons and their contributions to gross neuronal shape. It specifically requires an explanation of which molecule does not contribute to this structure.

More Information

Microtubules, actin filaments, and microtubule-associated proteins (such as MAP-2 and Tau) are key components of the cytoskeleton. Synaptotagmin, however, is involved in synaptic vesicle fusion and is not part of the cytoskeletal architecture.

Tips

Common mistakes include confusing protein functions and assuming all listed proteins are structural.

Sources

• Tau protein (MAPT) as a microtubule-associated protein - pmc.ncbi.nlm.nih.gov