Which equation represents the relationship between pH and the solubility of an acidic drug?
Understand the Problem
The question is asking which of the given equations correctly represents the relationship between pH and the solubility of an acidic drug. To answer it, we need to analyze each equation in terms of the established principles of acid-base chemistry and solubility.
Answer
The Henderson-Hasselbalch equation.
The equation that represents the relationship between pH and the solubility of an acidic drug is the Henderson-Hasselbalch equation.
Answer for screen readers
The equation that represents the relationship between pH and the solubility of an acidic drug is the Henderson-Hasselbalch equation.
More Information
The Henderson-Hasselbalch equation is widely used to estimate the pH of a buffer solution and understand the ionization state of a drug at different pH levels, which affects its solubility.
Tips
Confusing pKa with pH is common. Remember that pKa is a constant specific to the substance, while pH is the property of the solution.
Sources
- The Henderson–Hasselbalch Equation - ScienceDirect - sciencedirect.com
- pH, pKa, and the Henderson-Hasselbalch Equation - ThoughtCo - thoughtco.com
AI-generated content may contain errors. Please verify critical information
