What might be predicted to happen when the following substance undergoes Friedel-Crafts acylation?
Understand the Problem
The question is asking what the outcome will be when a specific compound undergoes Friedel-Crafts acylation, focusing on the orientation of the substitution in relation to the substituents on the aromatic rings.
Answer
Substitution occurs in ring B, para to the methylene group.
The final answer is: Substitution occurs in ring B, para to the methylene group.
Answer for screen readers
The final answer is: Substitution occurs in ring B, para to the methylene group.
More Information
The nitro group on ring A is a deactivating meta-director, making ring A less reactive to Friedel-Crafts acylation. The methylene bridge directs electrophilic substitution to the para position on ring B, an otherwise unsubstituted and more reactive site.
Tips
A common mistake is not recognizing the influence of the methylene bridge on directing the substitution towards ring B's para position.
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