What is the role of the 5′ untranslated region (5′ UTR) in mRNA?
Understand the Problem
The question is asking about the function of the 5′ untranslated region (5′ UTR) in mRNA. It provides multiple choice options to identify its role, specifically focusing on whether it influences translation, gene expression, or is translated into protein.
Answer
The 5′ UTR is critical for ribosome recruitment, start codon choice, translation efficiency, mRNA stability, and shaping the cellular proteome.
The final answer is that the 5′ untranslated region (5′ UTR) is critical for ribosome recruitment, start codon choice, control of translation efficiency, mRNA stability, and shaping the cellular proteome.
Answer for screen readers
The final answer is that the 5′ untranslated region (5′ UTR) is critical for ribosome recruitment, start codon choice, control of translation efficiency, mRNA stability, and shaping the cellular proteome.
More Information
The 5′ UTR can affect the stability, localization, and rate of translation of mRNA, thereby playing a key role in post-transcriptional regulation of gene expression.
Sources
- The Functional Meaning of 5′UTR in Protein-Coding Genes - PMC - ncbi.nlm.nih.gov
- Five prime untranslated region - Wikipedia - en.wikipedia.org
- A 5′ UTR language model for decoding untranslated regions of... - nature.com