What is the primary pathophysiological mechanism leading to osteoporosis in older adults? A) Increased osteoblast activity B) Decreased osteoclast activity C) Increased osteoclast... What is the primary pathophysiological mechanism leading to osteoporosis in older adults? A) Increased osteoblast activity B) Decreased osteoclast activity C) Increased osteoclast activity D) Hypercalcemia
Understand the Problem
The question is asking about the primary pathophysiological mechanism that causes osteoporosis in older adults and presents multiple-choice answers related to bone activity.
Answer
Increased osteoclast activity.
The primary pathophysiological mechanism leading to osteoporosis in older adults is increased osteoclast activity.
Answer for screen readers
The primary pathophysiological mechanism leading to osteoporosis in older adults is increased osteoclast activity.
More Information
Osteoporosis is primarily caused by the increased activity of osteoclasts, which leads to bone resorption that exceeds bone formation. This process is often exacerbated by factors like estrogen deficiency and aging.
Tips
Confusing osteoclast and osteoblast activity is common. Osteoclasts are responsible for bone resorption, while osteoblasts are involved in bone formation.
Sources
- The Epidemiology and Pathogenesis of Osteoporosis - NCBI - ncbi.nlm.nih.gov
- Pathophysiology and treatment of osteoporosis - PubMed Central - pmc.ncbi.nlm.nih.gov
- Osteoporosis: Practice Essentials, Background, Pathophysiology - emedicine.medscape.com
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