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Understand the Problem

The question is asking about the process of transcription activation involving histones and various factors, as illustrated in the provided image. It aims to clarify how transcription factors and modifications of histones lead to the activation of transcription.

Answer

Histone modifications enable transcription by chromatin remodeling.

The image depicts transcription activation through histone modifications like acetylation by histone acetyltransferase and phosphorylation by histone kinase. These modifications facilitate chromatin remodeling and the assembly of transcription machinery, enabling transcription to occur.

Answer for screen readers

The image depicts transcription activation through histone modifications like acetylation by histone acetyltransferase and phosphorylation by histone kinase. These modifications facilitate chromatin remodeling and the assembly of transcription machinery, enabling transcription to occur.

More Information

Histone acetylation generally neutralizes positive charges, reducing DNA-histone interaction and making DNA more accessible for transcription.

Tips

A common mistake is confusing methylation with acetylation, which have different effects on gene expression.

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