Wound Healing and Tissue Regeneration Quiz

<p>Liver parenchymal cells (C)</p> Signup and view all the answers

<p>Directly stimulating cell growth by producing growth factors (B)</p> Signup and view all the answers

<p>Macrophages (B)</p> Signup and view all the answers

<p>Cardiac muscle cells (B)</p> Signup and view all the answers

<p>Growth factors (D)</p> Signup and view all the answers

<p>Vascular endothelial growth factor (VEGF) (B)</p> Signup and view all the answers

<p>They release pro-inflammatory cytokines that contribute to the inflammatory cascade and prevent infection. (C)</p> Signup and view all the answers

<p>It influences the speed at which the healing process occurs. (A)</p> Signup and view all the answers

<p>Excessive inflammation. (D)</p> Signup and view all the answers

<p>Proliferation (D)</p> Signup and view all the answers

<p>Hemostasis is a short-lived process, lasting only seconds after injury. (A)</p> Signup and view all the answers

<p>It is a complex cascade of events characterized by the recruitment of different inflammatory cells. (A)</p> Signup and view all the answers

<p>Increased scar formation and impaired tissue regeneration. (B)</p> Signup and view all the answers

<p>Macrophages (C)</p> Signup and view all the answers

<p>Granulation tissue phase (C)</p> Signup and view all the answers

<p>Presence of foreign bodies (D)</p> Signup and view all the answers

<p>Wound contraction by myofibroblasts (D)</p> Signup and view all the answers

<p>Hypertrophic scar (A)</p> Signup and view all the answers

<p>4 weeks (B)</p> Signup and view all the answers

<p>They migrate and proliferate (B)</p> Signup and view all the answers

<p>Good nutritional status (D)</p> Signup and view all the answers

<p>Wound rupture (A)</p> Signup and view all the answers

<p>Deep red and granular (C)</p> Signup and view all the answers

<p>Significant tissue loss (C)</p> Signup and view all the answers

<p>Osteomyelitis (A)</p> Signup and view all the answers

<p>Age-related vascular changes (C)</p> Signup and view all the answers

<p>Pale and less vascularized (D)</p> Signup and view all the answers

<p>Keloid (D)</p> Signup and view all the answers

<p>Excessive abdominal pressure (B)</p> Signup and view all the answers

<p>Production of elastin and organization of the extracellular matrix (A)</p> Signup and view all the answers

<p>Growth factor (GF) (D)</p> Signup and view all the answers

<p>Degree of tissue loss and wound closure technique (A)</p> Signup and view all the answers

<p>Myofibroblasts (B)</p> Signup and view all the answers

<p>Months to years (C)</p> Signup and view all the answers

<p>Hypertrophic scars or keloids (B)</p> Signup and view all the answers

<p>FGF2 and TGF-β (A)</p> Signup and view all the answers

<p>Disappearance of vessels and inflammatory cells (D)</p> Signup and view all the answers

<p>Migration and proliferation of keratinocytes (C)</p> Signup and view all the answers

<p>VEGF (C)</p> Signup and view all the answers

<p>They are leaky and contribute to tissue edema. (A)</p> Signup and view all the answers

<p>Thin-walled capillaries and fibroblasts (B)</p> Signup and view all the answers

<p>Facilitate proteolytic degradation of the basement membrane (C)</p> Signup and view all the answers

<p>Fibroblasts (D)</p> Signup and view all the answers

<p>Vessels are remodeled and organized into capillary tubes. (D)</p> Signup and view all the answers

<p>24 hours post-wounding (B)</p> Signup and view all the answers

The body's response to injury for restoration of normal structure and function.

A process where tissues replace damaged components and return to a normal state.

Healing that involves proliferation of connective tissue, resulting in fibrosis and scarring.

Cells that continuously divide throughout life and can easily regenerate after injury.

Cells that lose ability to proliferate after adolescence but can still multiply in response to stimuli.

Cells that lose proliferative ability around birth and cannot regenerate, leading to scarring.

Classification of cells based on their ability to divide and regenerate after injury.

Substances important for tissue repair, aiding in the healing process.

ECM provides mechanical support and determines cell polarity and growth.

Four overlapping phases: Hemostasis, Inflammation, Proliferation, Remodeling.

Immediate response to injury involving vascular constriction and clot formation.

Occurs 1-2 days post-injury, led by inflammatory cells like PMNs and macrophages.

Molecules released by PMNs that drive inflammation, crucial for fighting infection.

Phase when new tissue forms consisting of collagen and extracellular matrix.

Localized conditions in tissues essential for proper cell function and proliferation.

The movement of inflammatory cells towards the wound site due to chemical signals.

A chemical modification essential for collagen maturation that requires oxygen.

Cells responsible for producing elastin and organizing the extracellular matrix (ECM).

A network that supports cell migration and modulates growth factor release.

The process where the extracellular matrix composition changes during wound healing.

Substances like TNF-α and TGF-β that regulate the remodeling phase of wounds.

Contractile fibroblasts that aid in physical contraction during wound healing.

A method of wound healing characterized by clean, approximation of wound edges with minimal tissue loss.

Types of scars formed due to persistent cellularity at the wound site.

Initial immune reaction within 24 hours, featuring polymorphs and later macrophages.

Type of white blood cells that appear early in the healing process to fight infection.

Immune cells that clear debris and replace polymorphs by the third day.

Basal epidermal cells move towards the wound margins to repair skin.

New vascular tissue formed during healing, appears red and fragile.

Process where a wound shrinks in size, facilitated by myofibroblasts.

Type of healing involving larger tissue loss, often left open to granulate.

The recovery of a wound through the migration and proliferation of keratinocytes.

The formation of new blood vessels from existing ones, aiding tissue repair.

The accumulation of collagen fibers at a wound site to provide structure and support.

Enzymes that help degrade extracellular matrix components during tissue remodeling.

Various local and systemic factors that influence the healing process of wounds.

Factors affecting wound healing that are specific to the wound site, like infection and blood supply.

Factors affecting healing that are related to the overall health of the individual, such as age and diabetes.

The unintentional reopening of a wound, often occurring post-surgery due to pressure.

A raised scar that forms within the boundaries of the original wound due to excess collagen.

A type of scar that grows beyond the original wound boundaries and does not regress.

A bone infection that can occur from chronic wounds, spreading to underlying bone.