Viral Host Range Determination Technologies
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Questions and Answers

What is the main purpose of attachment and entry in the infectious cycle of a virus?

  • To facilitate gene expression
  • To replicate the viral genome
  • To allow the virus to enter the host cell (correct)
  • To assemble and release new virus particles

What defines a susceptible cell in virology terms?

  • A cell that can support viral replication (correct)
  • A cell that is resistant to viral replication
  • A cell that is too large to uptake virus particles
  • A cell that has no receptor for the virus

What technology advancement allowed the determination of viral receptors?

  • Western blotting
  • Mass spectrometry
  • Flow cytometry (correct)
  • Polymerase chain reaction (PCR)

Why are viruses considered obligate intracellular parasites?

<p>Because they require host cells to replicate (A)</p> Signup and view all the answers

Which of the following is a criteria for a genuine virus receptor?

<p>Disruption of the receptor gene should enhance infection (D)</p> Signup and view all the answers

What is the first step in the attachment process of a virus to a host cell?

<p>Random collisions and electrostatic interactions (B)</p> Signup and view all the answers

What role do virion cellular receptors play in the infectious cycle?

<p>Bind the virus particle and assist in entry into the cell (A)</p> Signup and view all the answers

Which molecule is known as the receptor for SARS-CoV-2?

<p>ACE2 (A)</p> Signup and view all the answers

What determines the host range of a virus?

<p>Presence of host cell receptors (C)</p> Signup and view all the answers

What distinguishes a permissive cell from a susceptible cell in terms of virus infection?

<p>Permissive cells can support viral replication (A)</p> Signup and view all the answers

Which two viruses share a common primary receptor?

<p>Adenovirus and Coxsackievirus B3 (D)</p> Signup and view all the answers

How do viruses attach to receptors?

<p>By fusing their envelope with the host cell membrane (D)</p> Signup and view all the answers

What specific protein does the viral fusion protein bind to in the endosome membrane?

<p>Niemann-Pick C1 protein (NPC1-protein) (B)</p> Signup and view all the answers

In what condition must viral fusion not occur?

<p>Neutral pH (plasma membrane) (A)</p> Signup and view all the answers

How are genomes released from non-enveloped viruses?

<p>Uncoating at nuclear pore complex (D)</p> Signup and view all the answers

What is a common feature of viruses infecting plant cells?

<p>Utilize plasmodesmata for intercellular movement (C)</p> Signup and view all the answers

What is the role of motor proteins in adenovirus infection?

<p>Assist in virion transport within the host cell (B)</p> Signup and view all the answers

How do some viruses breach the strong cell wall of bacterial cells?

<p>By exploiting specialized structures on the bacterial surface (A)</p> Signup and view all the answers

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