Viral Host Range Determination Technologies
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Questions and Answers

What is the main purpose of attachment and entry in the infectious cycle of a virus?

  • To facilitate gene expression
  • To replicate the viral genome
  • To allow the virus to enter the host cell (correct)
  • To assemble and release new virus particles
  • What defines a susceptible cell in virology terms?

  • A cell that can support viral replication (correct)
  • A cell that is resistant to viral replication
  • A cell that is too large to uptake virus particles
  • A cell that has no receptor for the virus
  • What technology advancement allowed the determination of viral receptors?

  • Western blotting
  • Mass spectrometry
  • Flow cytometry (correct)
  • Polymerase chain reaction (PCR)
  • Why are viruses considered obligate intracellular parasites?

    <p>Because they require host cells to replicate</p> Signup and view all the answers

    Which of the following is a criteria for a genuine virus receptor?

    <p>Disruption of the receptor gene should enhance infection</p> Signup and view all the answers

    What is the first step in the attachment process of a virus to a host cell?

    <p>Random collisions and electrostatic interactions</p> Signup and view all the answers

    What role do virion cellular receptors play in the infectious cycle?

    <p>Bind the virus particle and assist in entry into the cell</p> Signup and view all the answers

    Which molecule is known as the receptor for SARS-CoV-2?

    <p>ACE2</p> Signup and view all the answers

    What determines the host range of a virus?

    <p>Presence of host cell receptors</p> Signup and view all the answers

    What distinguishes a permissive cell from a susceptible cell in terms of virus infection?

    <p>Permissive cells can support viral replication</p> Signup and view all the answers

    Which two viruses share a common primary receptor?

    <p>Adenovirus and Coxsackievirus B3</p> Signup and view all the answers

    How do viruses attach to receptors?

    <p>By fusing their envelope with the host cell membrane</p> Signup and view all the answers

    What specific protein does the viral fusion protein bind to in the endosome membrane?

    <p>Niemann-Pick C1 protein (NPC1-protein)</p> Signup and view all the answers

    In what condition must viral fusion not occur?

    <p>Neutral pH (plasma membrane)</p> Signup and view all the answers

    How are genomes released from non-enveloped viruses?

    <p>Uncoating at nuclear pore complex</p> Signup and view all the answers

    What is a common feature of viruses infecting plant cells?

    <p>Utilize plasmodesmata for intercellular movement</p> Signup and view all the answers

    What is the role of motor proteins in adenovirus infection?

    <p>Assist in virion transport within the host cell</p> Signup and view all the answers

    How do some viruses breach the strong cell wall of bacterial cells?

    <p>By exploiting specialized structures on the bacterial surface</p> Signup and view all the answers

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