Viral Effects on Host Cells Quiz

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Questions and Answers

Which of the following is NOT an important event in viral pathogenesis?

  • Viral entry into the host
  • The elimination of the virus by the host organism
  • The formation of the virion (correct)
  • Viral replication in the place of first implant

Which route of viral penetration is less common but still frequent?

  • Skin lesion route
  • Genital route (correct)
  • Respiratory route
  • Gastrointestinal route

What determines the virulence of each type of virus?

  • The permissiveness of the host and its organs
  • Small mutations in the genome (correct)
  • The location of the first implant
  • The pathogenic activity of the virus itself

Which route of transmission is influenced by social and economic conditions and is commonly associated with contaminated food?

<p>Gastrointestinal tract (D)</p> Signup and view all the answers

Which virus can be transmitted through breast-feeding and can be reduced by early treatment after birth of HIV newborn?

<p>HIV (B)</p> Signup and view all the answers

Which type of infection is restricted to certain areas but can have generalized effects on the body?

<p>Localized infections (C)</p> Signup and view all the answers

Which route of dissemination is the most common for viruses?

<p>Systemic blood (C)</p> Signup and view all the answers

Which of the following is a possible mode of viral elimination?

<p>Airway (D)</p> Signup and view all the answers

Which viruses are known to spread through the nervous route?

<p>Rhabdoviruses (C)</p> Signup and view all the answers

What is the difference between incubation period and generation time?

<p>Generation time refers to transmission to another individual (A)</p> Signup and view all the answers

What is a characteristic of chronic viral infections?

<p>The acute stage is absent (B)</p> Signup and view all the answers

Which virus is associated with primary hepatocellular carcinoma?

<p>Hepatitis B virus (D)</p> Signup and view all the answers

Which virus is the causative agent of Burkitt lymphoma with the translocation of c-myc oncogene?

<p>Epstein-Barr virus (D)</p> Signup and view all the answers

Which virus is associated with cervical cancer?

<p>Human papillomavirus (D)</p> Signup and view all the answers

Which virus is associated with Kaposi's sarcoma and primary effusion lymphoma?

<p>Human herpesvirus 8 (A)</p> Signup and view all the answers

Which of the following is a characteristic of cytopathic effect (CPE)?

<p>Formation of multinucleated giant cells (B)</p> Signup and view all the answers

What is the purpose of apoptosis in virus-infected cells?

<p>To prevent the spread of the virus within the host organism (A)</p> Signup and view all the answers

Which of the following viruses is capable of inhibiting the expression of proteins directly involved in apoptosis and their related targets?

<p>CMV (D)</p> Signup and view all the answers

What is transformation in the context of virus-host cell interactions?

<p>The process by which a cell loses control of its proliferation and becomes cancerous (B)</p> Signup and view all the answers

Which phase of the multifactorial process of tumor formation involves the indefinite multiplication of cells with the formation of lines or clones?

<p>Immortalization (B)</p> Signup and view all the answers

What is the role of oncogenes in normal cell proliferation?

<p>They are necessary for cellular homeostasis (D)</p> Signup and view all the answers

What percentage of human cancers has a viral etiology, according to the text?

<p>15% (A)</p> Signup and view all the answers

Which RNA virus can cause transformation during permissive infections?

<p>Human T-cell lymphotropic virus type 1 (HTLV-1) (C)</p> Signup and view all the answers

Which of the following is an important event in viral pathogenesis?

<p>Overcoming of local defenses (D)</p> Signup and view all the answers

Which of the following is a common route of viral penetration?

<p>Respiratory route (A)</p> Signup and view all the answers

What determines the virulence of a virus?

<p>The permissiveness of the host and its organs (D)</p> Signup and view all the answers

Which virus can be transmitted from mother to child through breast-feeding?

<p>HIV (A)</p> Signup and view all the answers

Which of the following is a common route of transmission for viruses that is influenced by social and economic conditions?

<p>Gastrointestinal route (A)</p> Signup and view all the answers

Which of the following is a less common but still frequent route of transmission for viruses that interests adults only?

<p>Genital route (C)</p> Signup and view all the answers

Which of the following is a characteristic of localized infections caused by viruses?

<p>They remain confined to the tissues of the site of entry or to those adjacent to it (A)</p> Signup and view all the answers

Which of the following is a characteristic of oncogenes?

<p>They may lead to neoplastic transformation (B)</p> Signup and view all the answers

Which virus is associated with adult T-cell leukemia?

<p>HTLV-1 (D)</p> Signup and view all the answers

What is the difference between initiators and promoters in the context of tumorigenesis?

<p>Initiators induce heritable changes in some cells, promoters cause the formation of the tumor (D)</p> Signup and view all the answers

Which of the following is a characteristic of complete carcinogens?

<p>They are capable of initiatives and promotions (A)</p> Signup and view all the answers

What is the cytopathic effect (CPE)?

<p>Morphological alterations that occur in host and cell cultures in vitro (A)</p> Signup and view all the answers

What is apoptosis?

<p>Programmed cell death (D)</p> Signup and view all the answers

What is transformation?

<p>The process by which a cell loses control of its proliferation and becomes cancerous (D)</p> Signup and view all the answers

What is the purpose of apoptosis in virus-infected cells?

<p>To prevent the spread of the virus within the host organism (C)</p> Signup and view all the answers

Which virus is associated with Merkel cell carcinoma?

<p>Polyomavirus (B)</p> Signup and view all the answers

Which virus is NOT associated with cervical cancer?

<p>Epstein-Barr virus (EBV) (C)</p> Signup and view all the answers

Which virus is associated with nasopharyngeal carcinoma?

<p>Epstein-Barr virus (EBV) (D)</p> Signup and view all the answers

Which virus is associated with anogenital cancers and Epidermodysplasia verruciformis?

<p>Human papillomavirus (HPV) (B)</p> Signup and view all the answers

Which of the following is a characteristic of latent infections?

<p>The virus remains in the form of integrated nucleic acid into the host cell genome or present in the cell nucleus in the episomic form. (A)</p> Signup and view all the answers

Which of the following is a characteristic of chronic infections?

<p>The virus is continuously produced even after the acute phase, usually at much lower levels and for a long time. (B)</p> Signup and view all the answers

Which of the following is a characteristic of slow infections?

<p>The acute stage is completely absent and the disease is characterized by a long incubation period that can last several years, followed by a progressive disease. (C)</p> Signup and view all the answers

Which of the following is a possible mode of viral elimination?

<p>Airway (B)</p> Signup and view all the answers

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