35 Questions
What are the three main divisions of viral host interactions according to the text?
Host barriers, viral replication, pathogenesis of viral infections
How do host defenses act on virus replication according to the text?
By altering or killing the infected cell
What are the general principles of virus-host interactions according to the text?
Inherent barriers, humoral components, cellular components
What does recovery from viral infections depend on according to the text?
The interactions between virus and host
What is the function of non-specific host defenses according to the text?
To limit infection or prevent infection
Which of the following can help to inhibit virus replication by decreasing virus replication?
Fever
What is the principal source of Interferon Alpha?
Leukocytes
What is the mechanism of action of antibody + complement in damaging the virus envelope?
Blocks entry into cell
In viral replication, what is the physical separation of the viral nucleic acid from the outer structural components of the virus called?
Uncoating
Which type of interferon has more than 20 genes?
Interferon Alpha
What is the effect of antibody alone in viral replication?
Blocks uncoating of virus
Which step in viral replication involves the synthesis of viral protein?
Translation
What is the mode of entry for non-enveloped viruses into the cell?
Direct penetration
Which component involved in resistance to viral infections is NOT specific?
'Cytokines'
'ADCC' (Antibody Dependent Cell-mediated Cytotoxicity) can be carried out by which cells?
'Natural killer cells'
What are the early nonspecific responses in viral infections targeted at?
Phagocytosis
Which component is NOT involved in host effector functions in viral infections?
Ciliated epithelium
What is the primary determinant for the variation in host defense mechanisms against a viral infection?
The virus, dose, and portal of entry
Which type of defense functions early in the encounter with a virus to prevent or limit infection?
Non-specific host defenses
What is the primary function of antibody + complement in relation to damaging the virus envelope?
Damaging the virus envelope
Which component is involved in resistance to viral infections and is specific in nature?
Humoral components
What is the mode of action of Interferon Alpha in inhibiting virus replication?
Inhibiting virus replication by decreasing virus replication
What is the principal source of Interferon Alpha during viral infections?
Infected host cells
What is the role of low pH in inhibiting viral infections?
Inactivates viruses by lowering their pH sensitivity
Which component is NOT a humoral component involved in resistance to viral infections?
Natural killer cells
What is the principal source of Interferon Beta?
Fibroblasts
What is the mechanism of action of antibody + complement in damaging the virus envelope?
Opsonization of virus
What step in viral replication involves the synthesis of viral protein?
Transcription
What is the effect of antibody alone in viral replication?
Blocks uncoating of virus
Which type of interferon has pH2 stability?
Interferon Alpha
'ADCC' (Antibody Dependent Cell-mediated Cytotoxicity) can be carried out by which cells?
Natural killer cells and T lymphocytes
What is the mode of entry for non-enveloped viruses into the cell?
Direct penetration
What are the early nonspecific responses in viral infections targeted at?
Virus replication
What does recovery from viral infections depend on according to the text?
Effectiveness of host defenses
What are the general principles of virus-host interactions according to the text?
Virus replication and assembly of new virus particles
Learn about the interaction between viruses and their hosts, including host barriers, immune responses, viral replication, and pathogenesis of viral infections. Understand how resistance to and recovery from viral infections depend on these interactions.
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