Viral-Host Interaction and Replication of Viruses
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Viral-Host Interaction and Replication of Viruses

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Questions and Answers

What are the three main divisions of viral host interactions according to the text?

  • Host barriers, viral replication, pathogenesis of viral infections (correct)
  • Host immunity, viral spread, viral entry
  • Viral replication, host resistance, immune response
  • Viral defense, host recovery, viral pathogenesis
  • How do host defenses act on virus replication according to the text?

  • By inducing viral replication
  • By directly attacking the virus
  • By altering or killing the infected cell (correct)
  • By promoting the spread of the virus
  • What are the general principles of virus-host interactions according to the text?

  • Inherent barriers, humoral components, cellular components (correct)
  • Host barriers, immune response, viral dose
  • Induced barriers, specific defenses, viral resistance
  • Viral entry, host recovery, pathogenesis
  • What does recovery from viral infections depend on according to the text?

    <p>The interactions between virus and host</p> Signup and view all the answers

    What is the function of non-specific host defenses according to the text?

    <p>To limit infection or prevent infection</p> Signup and view all the answers

    Which of the following can help to inhibit virus replication by decreasing virus replication?

    <p>Fever</p> Signup and view all the answers

    What is the principal source of Interferon Alpha?

    <p>Leukocytes</p> Signup and view all the answers

    What is the mechanism of action of antibody + complement in damaging the virus envelope?

    <p>Blocks entry into cell</p> Signup and view all the answers

    In viral replication, what is the physical separation of the viral nucleic acid from the outer structural components of the virus called?

    <p>Uncoating</p> Signup and view all the answers

    Which type of interferon has more than 20 genes?

    <p>Interferon Alpha</p> Signup and view all the answers

    What is the effect of antibody alone in viral replication?

    <p>Blocks uncoating of virus</p> Signup and view all the answers

    Which step in viral replication involves the synthesis of viral protein?

    <p>Translation</p> Signup and view all the answers

    What is the mode of entry for non-enveloped viruses into the cell?

    <p>Direct penetration</p> Signup and view all the answers

    Which component involved in resistance to viral infections is NOT specific?

    <p>'Cytokines'</p> Signup and view all the answers

    'ADCC' (Antibody Dependent Cell-mediated Cytotoxicity) can be carried out by which cells?

    <p>'Natural killer cells'</p> Signup and view all the answers

    What are the early nonspecific responses in viral infections targeted at?

    <p>Phagocytosis</p> Signup and view all the answers

    Which component is NOT involved in host effector functions in viral infections?

    <p>Ciliated epithelium</p> Signup and view all the answers

    What is the primary determinant for the variation in host defense mechanisms against a viral infection?

    <p>The virus, dose, and portal of entry</p> Signup and view all the answers

    Which type of defense functions early in the encounter with a virus to prevent or limit infection?

    <p>Non-specific host defenses</p> Signup and view all the answers

    What is the primary function of antibody + complement in relation to damaging the virus envelope?

    <p>Damaging the virus envelope</p> Signup and view all the answers

    Which component is involved in resistance to viral infections and is specific in nature?

    <p>Humoral components</p> Signup and view all the answers

    What is the mode of action of Interferon Alpha in inhibiting virus replication?

    <p>Inhibiting virus replication by decreasing virus replication</p> Signup and view all the answers

    What is the principal source of Interferon Alpha during viral infections?

    <p>Infected host cells</p> Signup and view all the answers

    What is the role of low pH in inhibiting viral infections?

    <p>Inactivates viruses by lowering their pH sensitivity</p> Signup and view all the answers

    Which component is NOT a humoral component involved in resistance to viral infections?

    <p>Natural killer cells</p> Signup and view all the answers

    What is the principal source of Interferon Beta?

    <p>Fibroblasts</p> Signup and view all the answers

    What is the mechanism of action of antibody + complement in damaging the virus envelope?

    <p>Opsonization of virus</p> Signup and view all the answers

    What step in viral replication involves the synthesis of viral protein?

    <p>Transcription</p> Signup and view all the answers

    What is the effect of antibody alone in viral replication?

    <p>Blocks uncoating of virus</p> Signup and view all the answers

    Which type of interferon has pH2 stability?

    <p>Interferon Alpha</p> Signup and view all the answers

    'ADCC' (Antibody Dependent Cell-mediated Cytotoxicity) can be carried out by which cells?

    <p>Natural killer cells and T lymphocytes</p> Signup and view all the answers

    What is the mode of entry for non-enveloped viruses into the cell?

    <p>Direct penetration</p> Signup and view all the answers

    What are the early nonspecific responses in viral infections targeted at?

    <p>Virus replication</p> Signup and view all the answers

    What does recovery from viral infections depend on according to the text?

    <p>Effectiveness of host defenses</p> Signup and view all the answers

    What are the general principles of virus-host interactions according to the text?

    <p>Virus replication and assembly of new virus particles</p> Signup and view all the answers

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