Vasodilators and Edema Formation Quiz
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Questions and Answers

Which of the following is a calcium channel blocker commonly used to treat hypertension?

  • Benazepril
  • Lacidipine (correct)
  • Enalapril
  • Captopril

What side effect is commonly associated with ACE inhibitors but not with calcium channel blockers?

  • Nausea
  • Headache
  • Dry cough (correct)
  • Dizziness

Which of the following is NOT a prodrug among the listed ACE inhibitors?

  • Lisinopril
  • Benazepril
  • Captopril (correct)
  • Enalapril

What essential elements are required for the active sites of ACE inhibitors according to the text?

<p>Zinc and Arginine (C)</p> Signup and view all the answers

Which medication is NOT classified as an angiotensin II receptor blocker?

<p>Lercanidipine (B)</p> Signup and view all the answers

What is the main purpose of RAAS modifiers according to the text?

<p>Avoid vasoconstriction (D)</p> Signup and view all the answers

What is the mechanism of action of PDEV inhibitors like Sildenafil (Viagra) in the context of vasodilation?

<p>Blocks T-type Ca2+ channels in CNS (B)</p> Signup and view all the answers

Which of the following is NOT a PDEV inhibitor used for vasodilation?

<p>Bepridil (B)</p> Signup and view all the answers

How do non-dihydropyridine calcium channel blockers (CCBs) like Verapamil affect the heart rate?

<p>Block L-type Ca2+ channels in cardiac muscles to decrease heart rate (D)</p> Signup and view all the answers

What is the primary pharmacological effect of nitroglycerin (glyceryl trinitrate) as a nitrate vasodilator?

<p>Reduces blood pressure by dilating arteriolar smooth muscles (A)</p> Signup and view all the answers

Which type of calcium channel blockers (CCBs) are more likely to cause edema due to their mechanism of action?

<p>Dihydropyridines (DHPs) (B)</p> Signup and view all the answers

What is the effect of D₁ antagonists like Fenoldopam when blocked?

<p>Antihypertensive effect (B)</p> Signup and view all the answers

What is the mechanism of action of nitrovasodilators?

<p>Denitrification leading to release of nitrite which is converted to NO (D)</p> Signup and view all the answers

What is the role of phosphodiesterase (PDEV) inhibitors in vasodilation?

<p>Increasing levels of cGMP leading to vasodilation (A)</p> Signup and view all the answers

Which of the following is a common side effect associated with the overuse of nitrovasodilators?

<p>Headache that can wear off quickly (C)</p> Signup and view all the answers

What is the 'Monday Syndrome' associated with the use of nitroglycerin?

<p>Exacerbation of migraine headaches when exposed to nitrates on Monday (D)</p> Signup and view all the answers

Which medication is specifically used for angina and stroke among the listed nitrovasodilators?

<p>Isosorbide Mononitrate (Imdur®) (D)</p> Signup and view all the answers

What effect does excessive inhibition of phosphodiesterase (PDEV) have on the body when using nitrovasodilators?

<p>Induces priapism (B)</p> Signup and view all the answers

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