Vasodilators and Edema Formation Quiz

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Which of the following is a calcium channel blocker commonly used to treat hypertension?

Benazepril

Lacidipine (correct)

Enalapril

Captopril

What side effect is commonly associated with ACE inhibitors but not with calcium channel blockers?

Nausea

Headache

Dry cough (correct)

Dizziness

Which of the following is NOT a prodrug among the listed ACE inhibitors?

Lisinopril

Benazepril

Captopril (correct)

Enalapril

What essential elements are required for the active sites of ACE inhibitors according to the text?

Zinc and Arginine Signup and view all the answers

Which medication is NOT classified as an angiotensin II receptor blocker?

Lercanidipine Signup and view all the answers

What is the main purpose of RAAS modifiers according to the text?

Avoid vasoconstriction Signup and view all the answers

What is the mechanism of action of PDEV inhibitors like Sildenafil (Viagra) in the context of vasodilation?

Blocks T-type Ca2+ channels in CNS Signup and view all the answers

Which of the following is NOT a PDEV inhibitor used for vasodilation?

Bepridil Signup and view all the answers

How do non-dihydropyridine calcium channel blockers (CCBs) like Verapamil affect the heart rate?

Block L-type Ca2+ channels in cardiac muscles to decrease heart rate Signup and view all the answers

What is the primary pharmacological effect of nitroglycerin (glyceryl trinitrate) as a nitrate vasodilator?

Reduces blood pressure by dilating arteriolar smooth muscles Signup and view all the answers

Which type of calcium channel blockers (CCBs) are more likely to cause edema due to their mechanism of action?

Dihydropyridines (DHPs) Signup and view all the answers

What is the effect of D₁ antagonists like Fenoldopam when blocked?

Antihypertensive effect Signup and view all the answers

What is the mechanism of action of nitrovasodilators?

Denitrification leading to release of nitrite which is converted to NO Signup and view all the answers

What is the role of phosphodiesterase (PDEV) inhibitors in vasodilation?

Increasing levels of cGMP leading to vasodilation Signup and view all the answers

Which of the following is a common side effect associated with the overuse of nitrovasodilators?

Headache that can wear off quickly Signup and view all the answers

What is the 'Monday Syndrome' associated with the use of nitroglycerin?

Exacerbation of migraine headaches when exposed to nitrates on Monday Signup and view all the answers

Which medication is specifically used for angina and stroke among the listed nitrovasodilators?

Isosorbide Mononitrate (Imdur®) Signup and view all the answers

What effect does excessive inhibition of phosphodiesterase (PDEV) have on the body when using nitrovasodilators?

Induces priapism Signup and view all the answers