Understanding Minimal Effective Concentration (MEC) Quiz
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Questions and Answers

What is the primary purpose of maintaining serum drug levels above the minimal effective concentration (MEC)?

  • To ensure the antibiotic has a bacteriostatic effect
  • To halt the growth of the targeted microorganism (correct)
  • To broaden the spectrum of activity of the antibiotic
  • To increase the therapeutic index of the antibiotic
  • When a patient's recurrent urinary tract infection fails to respond to an antibiotic that has previously been effective, the most likely reason is:

  • Acquired bacterial resistance (correct)
  • Cross-resistance to other antibiotics
  • Inherent resistance of the bacteria
  • Transferred resistance from another patient
  • If a patient has previously experienced a severe rash when taking penicillin, what is the most appropriate action when considering administering amoxicillin (a penicillin derivative)?

  • Administer amoxicillin and have epinephrine available
  • Request an order for an antihistamine
  • Contact the provider about using a different antibiotic (correct)
  • Request an order for a beta-lactamase-resistant drug
  • When a patient has been receiving an antibiotic for 2 days after a culture was obtained, the nurse should:

    <p>Verify if the antibiotic should be continued pending culture results</p> Signup and view all the answers

    Which of the following best describes acquired bacterial resistance?

    <p>Bacteria develop resistance mechanisms through genetic mutations</p> Signup and view all the answers

    Which of the following statements about cross-resistance is accurate?

    <p>It occurs when bacteria develop resistance to multiple antibiotics from different classes</p> Signup and view all the answers

    What should a patient do if they develop a rash while taking a drug?

    <p>Stop taking the drug and call the provider</p> Signup and view all the answers

    Which foods should a patient avoid when taking amoxicillin?

    <p>Acidic fruits and juices</p> Signup and view all the answers

    What action should a nurse take when administering milky-colored penicillin G procaine?

    <p>Administer the medication as ordered by the physician</p> Signup and view all the answers

    What effect can azithromycin have on digoxin and warfarin?

    <p>Increased effectiveness of digoxin</p> Signup and view all the answers

    What is the best course of action if a patient reports having had a rash when taking penicillin?

    <p>Consider using erythromycin instead.</p> Signup and view all the answers

    What could be a potential consequence of treating viral infections with antibiotics?

    <p>Development of acquired resistance.</p> Signup and view all the answers

    How should a patient react if they experience gastric irritation when taking oral cephalosporins?

    <p>Take it with food.</p> Signup and view all the answers

    What is the most appropriate action for the nurse to take when noting increased erythema, swelling, and a persistent high fever in the patient?

    <p>Review the sensitivity results from the patient's culture</p> Signup and view all the answers

    Before administering the first dose of an antibiotic for a urinary tract infection, which action is most important for the nurse to take?

    <p>Obtain a urine specimen for culture and sensitivity</p> Signup and view all the answers

    If a patient is admitted for pneumonia but is unable to produce sputum for a culture, which antibiotic is the provider most likely to order?

    <p>A broad-spectrum antibiotic</p> Signup and view all the answers

    When teaching a patient who will be discharged on amoxicillin twice daily for ten days, which statement by the nurse is correct?

    <p>Stop taking the drug and notify your provider if you develop a rash while taking this drug.</p> Signup and view all the answers

    If a patient previously experienced a rash when taking amoxicillin, and the nurse is preparing to administer intravenous ceftriaxone, what is the most appropriate action?

    <p>Administer the drug and observe closely for hypersensitivity reactions</p> Signup and view all the answers

    If a patient has been receiving a cephalosporin antibiotic for two weeks and the nurse notes ulcers on the patient's tongue and buccal mucosa, what is the most appropriate action?

    <p>Report a possible side effect of the cephalosporin, such as superinfection</p> Signup and view all the answers

    When providing teaching to a patient who will begin taking a cephalosporin antibiotic, which statement by the patient indicates a need for further teaching?

    <p>I may stop taking the medication if my symptoms clear up.</p> Signup and view all the answers

    Which statement regarding the administration of intravenous ceftriaxone is accurate?

    <p>It should be administered through a dedicated IV line.</p> Signup and view all the answers

    Which statement regarding the use of cephalosporin antibiotics is true?

    <p>They are effective against both Gram-positive and Gram-negative bacteria.</p> Signup and view all the answers

    When administering an antibiotic, which action by the nurse is most important?

    <p>Verifying the dose and route of administration</p> Signup and view all the answers

    Which statement correctly describes the administration of azithromycin in relation to food?

    <p>Azithromycin should be taken 1 hour before or 2 hours after meals.</p> Signup and view all the answers

    What is the appropriate action for a nurse to take when a patient taking warfarin is prescribed clarithromycin?

    <p>Request an order for INR testing.</p> Signup and view all the answers

    Which macrolide antibiotic should be questioned by the nurse when a patient allergic to penicillin plans to take fluconazole concurrently?

    <p>Erythromycin</p> Signup and view all the answers

    What type of drug requires monitoring of serum peak and trough levels?

    <p>Drugs with a narrow therapeutic index</p> Signup and view all the answers

    If a patient's serum drug trough level is below the normal range, what effect should the nurse expect?

    <p>Inadequate therapeutic effects</p> Signup and view all the answers

    How should doxycycline, a tetracycline antibiotic, be administered in relation to food?

    <p>With food to improve absorption</p> Signup and view all the answers

    What is the recommended timing for taking azithromycin in relation to antacids?

    <p>Take azithromycin 2 hours before or 2 hours after antacids.</p> Signup and view all the answers

    Which statement is true regarding diarrhea as a side effect of azithromycin?

    <p>Watery diarrhea should be reported as it may indicate pseudomembranous colitis.</p> Signup and view all the answers

    What is the appropriate action for a nurse to take if a patient taking azithromycin reports a dairy product restriction?

    <p>Reassure the patient that there is no restriction for dairy products when taking azithromycin.</p> Signup and view all the answers

    Which statement correctly describes the appropriate action when a patient taking warfarin is prescribed clarithromycin?

    <p>Request an order for INR testing.</p> Signup and view all the answers

    What is the appropriate action for the nurse to take when noting increased erythema, swelling, and a persistent high fever in the patient?

    <p>Report possible drug toxicity to the patient's provider</p> Signup and view all the answers

    If a patient's serum drug trough level is below the normal range, what effect should the nurse expect?

    <p>The drug may be ineffective in treating the infection</p> Signup and view all the answers

    When a patient's recurrent urinary tract infection fails to respond to an antibiotic that has previously been effective, the most likely reason is:

    <p>The causative bacteria has developed resistance to the antibiotic</p> Signup and view all the answers

    Which statement correctly describes the appropriate action when a patient taking warfarin is prescribed clarithromycin?

    <p>Monitor the patient's INR and adjust the warfarin dose as needed</p> Signup and view all the answers

    What is the primary purpose of maintaining serum drug levels above the minimal effective concentration (MEC)?

    <p>To ensure the drug is effective in treating the infection</p> Signup and view all the answers

    Which statement regarding the use of cephalosporin antibiotics is true?

    <p>Cephalosporins have a higher risk of causing Clostridium difficile-associated diarrhea compared to other antibiotics</p> Signup and view all the answers

    Which laboratory values will the nurse expect to monitor when caring for a patient receiving a high tetracycline dose?

    <p>Blood urea nitrogen (BUN) and creatinine levels</p> Signup and view all the answers

    What information will the nurse include when teaching a female patient about taking doxycycline to treat a sexually transmitted infection (STI)?

    <p>Use a backup method of contraception if taking oral contraceptives.</p> Signup and view all the answers

    If an infant receiving intravenous gentamicin has not had a wet diaper for several hours, what action should the nurse perform?

    <p>Assess the infant's renal function and notify the provider</p> Signup and view all the answers

    Which of the following statements is true regarding the administration of doxycycline, a tetracycline antibiotic?

    <p>It should be taken with a backup contraceptive method if the patient is taking oral contraceptives.</p> Signup and view all the answers

    What is the primary purpose of maintaining serum drug levels above the minimal effective concentration (MEC) when administering antibiotics?

    <p>To ensure therapeutic efficacy and minimize toxicity</p> Signup and view all the answers

    What is the most appropriate action for a nurse to take if a patient previously experienced a severe rash when taking penicillin and is now being considered for amoxicillin (a penicillin derivative) administration?

    <p>Consult with the provider to determine if a penicillin skin test should be performed</p> Signup and view all the answers

    Which of the following side effects should a patient taking acyclovir be instructed to report to their provider?

    <p>Dizziness and confusion</p> Signup and view all the answers

    What is the most important instruction a nurse should give a patient prescribed acyclovir?

    <p>Increase fluid intake to maintain hydration</p> Signup and view all the answers

    Which of the following viruses is NOT caused by a herpes virus?

    <p>Influenza</p> Signup and view all the answers

    Which statement about metronidazole is FALSE?

    <p>Metronidazole is inappropriate for treating trichomoniasis because it is only indicated for bacterial infections</p> Signup and view all the answers

    When a patient is prescribed ivermectin to treat onchocerciasis and is also taking warfarin and atorvastatin, which of the following should the nurse recommend monitoring?

    <p>Coagulation parameters</p> Signup and view all the answers

    Which of the following is a common side effect associated with acyclovir use?

    <p>Acyclovir has very few side effects</p> Signup and view all the answers

    What is the most appropriate dose and frequency for acyclovir in an immunocompetent patient diagnosed with herpes zoster virus?

    <p>800 mg five times daily for 7 to 10 days</p> Signup and view all the answers

    Which statement is correct regarding the use of acyclovir for treating a herpes virus infection?

    <p>Acyclovir helps reduce the severity and duration of herpes virus outbreaks.</p> Signup and view all the answers

    Which of the following is a common side effect of acyclovir that the nurse should educate the patient about?

    <p>Nausea and vomiting</p> Signup and view all the answers

    When administering acyclovir, which of the following instructions should the nurse provide to the patient?

    <p>Take the medication with food or milk to reduce stomach upset.</p> Signup and view all the answers

    Which statement is true regarding the use of acyclovir in immunocompromised patients?

    <p>The duration of treatment may need to be extended.</p> Signup and view all the answers

    Which of the following statements about acyclovir administration is correct?

    <p>Acyclovir can be crushed and mixed with food for patients with difficulty swallowing.</p> Signup and view all the answers

    When administering clarithromycin to a patient taking warfarin, the nurse should:

    <p>Monitor prothrombin time (PT) and international normalized ratio (INR) levels closely</p> Signup and view all the answers

    If a patient reports watery diarrhea while taking azithromycin, the nurse should:

    <p>Discontinue the azithromycin and report the symptom</p> Signup and view all the answers

    When administering azithromycin, the nurse should instruct the patient to:

    <p>Take the medication 1 hour before or 2 hours after meals</p> Signup and view all the answers

    If a patient has previously experienced a severe rash when taking penicillin, the appropriate action when considering amoxicillin (a penicillin derivative) is:

    <p>Avoid prescribing amoxicillin due to the risk of cross-reactivity</p> Signup and view all the answers

    When monitoring a patient taking high doses of macrolide antibiotics, the nurse should expect to review which lab values?

    <p>Liver enzymes and urinalysis</p> Signup and view all the answers

    When administering intravenous ceftriaxone to a patient with a penicillin allergy, the nurse should:

    <p>Avoid administering ceftriaxone due to the risk of cross-reactivity</p> Signup and view all the answers

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