Questions and Answers
What is the classification of Thiamine?
What is the mechanism of action (MOA) of Thiamine?
Thiamine combines with ATP to produce Thiamine Diphosphate.
Which of the following are indications for using Thiamine? (Select all that apply)
What are the adverse effects of Thiamine?
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What is a contraindication for Thiamine?
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What is the adult dosage for Wernicke-Korsakoff syndrome?
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What is the pediatric dosage for Wernicke-Korsakoff syndrome?
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Study Notes
Thiamine (Vitamin B1) Overview
- Thiamine is classified as Vitamin B1, essential for human health.
Mechanism of Action (MOA)
- Combines with ATP to form Thiamine Diphosphate.
- Functions as a crucial coenzyme in carbohydrate metabolism, facilitating energy production.
Indications for Use
- Indicated for treatment of Wernicke-Korsakoff syndrome, a neurological disorder due to thiamine deficiency.
- Used to treat Beriberi, a condition associated with thiamine deficiency affecting the cardiovascular and nervous systems.
- Recommended for nutritional supplementation, especially in at-risk populations.
Adverse Effects
- Possible side effects include itching and rash, which may indicate allergic reactions.
- Local pain can occur at the injection site during administration.
Contraindications
- Contraindicated in individuals with known sensitivity to thiamine or its components.
Adult Dosage
- For Wernicke-Korsakoff syndrome, the recommended dosage is 100 mg administered via intravenous (IV) or intraosseous (IO) routes.
Pediatric Dosage
- Dosage for Wernicke-Korsakoff syndrome in pediatric patients is not recommended, indicating a lack of established safety or efficacy in children.
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Description
Test your knowledge of Thiamine, also known as Vitamin B1, with these flashcards. This quiz covers its classification, mechanism of action, indications for use, and potential adverse effects. Perfect for students and health professionals alike!
