Vitamin B1 (Thiamine) Sources and Functions
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Questions and Answers

Which of the following is the coenzyme form of vitamin B1 (thiamine)?

  • Thiamine pyrophosphate (TPP) (correct)
  • Niacin
  • Flavin adenine dinucleotide (FAD)
  • Flavin mononucleotide (FMN)
  • What is the primary function of thiamine pyrophosphate (TPP)?

  • Fatty acid oxidation
  • Citric acid cycle
  • Coenzyme for pyruvate dehydrogenase (which converts pyruvate to acetyl CoA) (correct)
  • Involved in mitochondrial respiratory chain
  • Which of the following is a manifestation of wet (cardiac) beriberi, a deficiency of vitamin B1?

  • Edema and difficulty in breathing (correct)
  • Angular stomatitis
  • Glossitis
  • Peripheral neuropathy
  • Which of the following vitamins is involved in mitochondrial respiratory chain, fatty acid oxidation, and citric acid cycle?

    <p>Vitamin B2 (riboflavin)</p> Signup and view all the answers

    Which of the following is a deficiency manifestation of riboflavin (vitamin B2)?

    <p>Angular stomatitis</p> Signup and view all the answers

    What is the recommended dietary allowance (RDA) for vitamin B1 (thiamine)?

    <p>1.0–1.5 mg (directly proportional to amount of carbohydrates in the diet)</p> Signup and view all the answers

    Which of the following is a good source of vitamin B2 (riboflavin)?

    <p>Milk and dairy products</p> Signup and view all the answers

    Which of the following is a manifestation of Wernicke's encephalopathy and Korsakoff's psychosis, seen in alcoholics with vitamin B1 deficiency?

    <p>All of the above</p> Signup and view all the answers

    What is the primary role of pyridoxine (vitamin B6) in relation to a high-protein diet?

    <p>It facilitates the metabolism and breakdown of proteins.</p> Signup and view all the answers

    What is the recommended daily allowance (RDA) for folic acid (vitamin B9)?

    <p>200 μg</p> Signup and view all the answers

    Which of the following is NOT a function of folic acid (vitamin B9)?

    <p>Regulation of blood glucose levels</p> Signup and view all the answers

    Which condition is NOT listed as a cause of folic acid deficiency?

    <p>Chronic kidney disease</p> Signup and view all the answers

    What is the primary manifestation of folic acid deficiency?

    <p>Megaloblastic anemia</p> Signup and view all the answers

    Which of the following is NOT a good dietary source of folic acid?

    <p>Citrus fruits</p> Signup and view all the answers

    What is the coenzyme form of folic acid?

    <p>Tetrahydrofolic acid (THFA)</p> Signup and view all the answers

    Which of the following is a potential adverse effect of the anticancer drug methotrexate?

    <p>Folic acid deficiency</p> Signup and view all the answers

    What is the main source of vitamin B12?

    <p>Meat, eggs, fish</p> Signup and view all the answers

    Which form of vitamin B12 is required for the enzyme methionine synthase?

    <p>Methylcobalamin</p> Signup and view all the answers

    What can cause a deficiency in vitamin B12 due to impaired absorption?

    <p>Lack of intrinsic factor</p> Signup and view all the answers

    Which manifestation is associated with megaloblastic anemia caused by a deficiency in vitamin B12?

    <p>Formation of megaloblasts leading to anemia</p> Signup and view all the answers

    What is the consequence of a deficiency in vitamin B12 regarding homocysteine levels?

    <p>Elevated homocysteine levels</p> Signup and view all the answers

    What neurological symptoms can occur due to a deficiency in vitamin B12?

    <p>Demyelination causing peripheral neuropathy and ataxia</p> Signup and view all the answers

    What enzymatic activity does deoxyadenosylcobalamin support?

    <p>Methylmalonyl-CoA mutase activity</p> Signup and view all the answers

    What group of individuals could be at risk for vitamin B12 deficiency due to decreased intake?

    <p>Vegans and vegetarians</p> Signup and view all the answers

    What is the primary function of vitamin B5 (pantothenic acid)?

    <p>Synthesis of fatty acids and cholesterol</p> Signup and view all the answers

    Which vitamin deficiency can lead to dermatitis and hair loss?

    <p>Vitamin B7 (biotin) deficiency</p> Signup and view all the answers

    What is the recommended dietary allowance (RDA) for vitamin C in adults?

    <p>75 mg</p> Signup and view all the answers

    Which of the following is NOT a function of vitamin C?

    <p>Synthesis of heme</p> Signup and view all the answers

    Which symptom is NOT associated with vitamin C deficiency (scurvy)?

    <p>Muscle cramps</p> Signup and view all the answers

    Which of the following is a good dietary source of vitamin B5 (pantothenic acid)?

    <p>Liver</p> Signup and view all the answers

    What is the coenzyme form of vitamin B5 (pantothenic acid) called?

    <p>Coenzyme A (CoA)</p> Signup and view all the answers

    What is the primary function of vitamin C in the body?

    <p>Collagen synthesis</p> Signup and view all the answers

    What is the primary function of NAD+ in the body?

    <p>Catabolism of carbohydrates and fats</p> Signup and view all the answers

    Which coenzyme functions more often in biosynthetic reactions like the synthesis of fatty acids and cholesterol?

    <p>Nicotinamide adenine dinucleotide phosphate (NADP+)</p> Signup and view all the answers

    What are the manifestations of niacin deficiency?

    <p>Dermatitis, diarrhea, dementia</p> Signup and view all the answers

    Which vitamin deficiency manifests as irritability, depression, confusion, and glossitis?

    <p>Vitamin B6 (pyridoxine) deficiency</p> Signup and view all the answers

    Inadequate dietary intake is a cause for deficiency of which coenzyme form?

    <p>Nicotinamide adenine dinucleotide (NAD+)</p> Signup and view all the answers

    Which coenzyme acts as a coenzyme for heme synthesis and glycogenolysis?

    <p>Pyridoxal phosphate (PLP)</p> Signup and view all the answers

    Which syndrome is associated with niacin deficiency?

    <p>Hartnup disease</p> Signup and view all the answers

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