Vitamin B1 (Thiamine) Sources and Functions
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Questions and Answers

Which of the following is the coenzyme form of vitamin B1 (thiamine)?

  • Thiamine pyrophosphate (TPP) (correct)
  • Niacin
  • Flavin adenine dinucleotide (FAD)
  • Flavin mononucleotide (FMN)

What is the primary function of thiamine pyrophosphate (TPP)?

  • Fatty acid oxidation
  • Citric acid cycle
  • Coenzyme for pyruvate dehydrogenase (which converts pyruvate to acetyl CoA) (correct)
  • Involved in mitochondrial respiratory chain

Which of the following is a manifestation of wet (cardiac) beriberi, a deficiency of vitamin B1?

  • Edema and difficulty in breathing (correct)
  • Angular stomatitis
  • Glossitis
  • Peripheral neuropathy

Which of the following vitamins is involved in mitochondrial respiratory chain, fatty acid oxidation, and citric acid cycle?

<p>Vitamin B2 (riboflavin) (B)</p> Signup and view all the answers

Which of the following is a deficiency manifestation of riboflavin (vitamin B2)?

<p>Angular stomatitis (D)</p> Signup and view all the answers

What is the recommended dietary allowance (RDA) for vitamin B1 (thiamine)?

<p>1.0–1.5 mg (directly proportional to amount of carbohydrates in the diet) (A)</p> Signup and view all the answers

Which of the following is a good source of vitamin B2 (riboflavin)?

<p>Milk and dairy products (D)</p> Signup and view all the answers

Which of the following is a manifestation of Wernicke's encephalopathy and Korsakoff's psychosis, seen in alcoholics with vitamin B1 deficiency?

<p>All of the above (D)</p> Signup and view all the answers

What is the primary role of pyridoxine (vitamin B6) in relation to a high-protein diet?

<p>It facilitates the metabolism and breakdown of proteins. (A)</p> Signup and view all the answers

What is the recommended daily allowance (RDA) for folic acid (vitamin B9)?

<p>200 μg (D)</p> Signup and view all the answers

Which of the following is NOT a function of folic acid (vitamin B9)?

<p>Regulation of blood glucose levels (D)</p> Signup and view all the answers

Which condition is NOT listed as a cause of folic acid deficiency?

<p>Chronic kidney disease (A)</p> Signup and view all the answers

What is the primary manifestation of folic acid deficiency?

<p>Megaloblastic anemia (C)</p> Signup and view all the answers

Which of the following is NOT a good dietary source of folic acid?

<p>Citrus fruits (B)</p> Signup and view all the answers

What is the coenzyme form of folic acid?

<p>Tetrahydrofolic acid (THFA) (A)</p> Signup and view all the answers

Which of the following is a potential adverse effect of the anticancer drug methotrexate?

<p>Folic acid deficiency (C)</p> Signup and view all the answers

What is the main source of vitamin B12?

<p>Meat, eggs, fish (B)</p> Signup and view all the answers

Which form of vitamin B12 is required for the enzyme methionine synthase?

<p>Methylcobalamin (C)</p> Signup and view all the answers

What can cause a deficiency in vitamin B12 due to impaired absorption?

<p>Lack of intrinsic factor (A)</p> Signup and view all the answers

Which manifestation is associated with megaloblastic anemia caused by a deficiency in vitamin B12?

<p>Formation of megaloblasts leading to anemia (D)</p> Signup and view all the answers

What is the consequence of a deficiency in vitamin B12 regarding homocysteine levels?

<p>Elevated homocysteine levels (B)</p> Signup and view all the answers

What neurological symptoms can occur due to a deficiency in vitamin B12?

<p>Demyelination causing peripheral neuropathy and ataxia (B)</p> Signup and view all the answers

What enzymatic activity does deoxyadenosylcobalamin support?

<p>Methylmalonyl-CoA mutase activity (D)</p> Signup and view all the answers

What group of individuals could be at risk for vitamin B12 deficiency due to decreased intake?

<p>Vegans and vegetarians (A)</p> Signup and view all the answers

What is the primary function of vitamin B5 (pantothenic acid)?

<p>Synthesis of fatty acids and cholesterol (D)</p> Signup and view all the answers

Which vitamin deficiency can lead to dermatitis and hair loss?

<p>Vitamin B7 (biotin) deficiency (C)</p> Signup and view all the answers

What is the recommended dietary allowance (RDA) for vitamin C in adults?

<p>75 mg (C)</p> Signup and view all the answers

Which of the following is NOT a function of vitamin C?

<p>Synthesis of heme (C)</p> Signup and view all the answers

Which symptom is NOT associated with vitamin C deficiency (scurvy)?

<p>Muscle cramps (C)</p> Signup and view all the answers

Which of the following is a good dietary source of vitamin B5 (pantothenic acid)?

<p>Liver (A)</p> Signup and view all the answers

What is the coenzyme form of vitamin B5 (pantothenic acid) called?

<p>Coenzyme A (CoA) (B)</p> Signup and view all the answers

What is the primary function of vitamin C in the body?

<p>Collagen synthesis (C)</p> Signup and view all the answers

What is the primary function of NAD+ in the body?

<p>Catabolism of carbohydrates and fats (B)</p> Signup and view all the answers

Which coenzyme functions more often in biosynthetic reactions like the synthesis of fatty acids and cholesterol?

<p>Nicotinamide adenine dinucleotide phosphate (NADP+) (C)</p> Signup and view all the answers

What are the manifestations of niacin deficiency?

<p>Dermatitis, diarrhea, dementia (C)</p> Signup and view all the answers

Which vitamin deficiency manifests as irritability, depression, confusion, and glossitis?

<p>Vitamin B6 (pyridoxine) deficiency (D)</p> Signup and view all the answers

Inadequate dietary intake is a cause for deficiency of which coenzyme form?

<p>Nicotinamide adenine dinucleotide (NAD+) (B)</p> Signup and view all the answers

Which coenzyme acts as a coenzyme for heme synthesis and glycogenolysis?

<p>Pyridoxal phosphate (PLP) (A)</p> Signup and view all the answers

Which syndrome is associated with niacin deficiency?

<p>Hartnup disease (B)</p> Signup and view all the answers

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