Questions and Answers
What is the relationship between thiamine requirement and carbohydrate intake?
Thiamine requirement increases as carbohydrate intake increases
What is the function of TPP in the TCA cycle?
All of the above
What is the consequence of reduced α-Ketoglutarate dehydrogenase activity?
Reduced oxidative decarboxylation of α-keto acids
What is the result of decreased Thiamine Pyrophosphate?
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What is the consequence of impaired conversion of pyruvate to acetyl-CoA?
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What is the role of RBC transketolase in measuring thiamine status?
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What is the coenzyme required for pyruvate dehydrogenase and α-Ketoglutarate dehydrogenase?
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What is the consequence of thiamine deficiency in individuals on a high-carbohydrate diet?
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What is the role of TPP in the catabolism of branched-chain amino acids?
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What is the main component of riboflavin?
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What is the role of FMN and FAD in redox reactions?
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What is the result of riboflavin deficiency?
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What is the byproduct of FMN and FAD accepting hydrogen atoms?
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What is the role of FAD in the Citric Acid Cycle?
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What is the role of FAD in the B-Oxidation of fatty acids?
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What is the biologically active form of riboflavin?
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What is the function of flavoenzymes?
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What is the role of riboflavin in energy production?
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What is the primary function of sphingomyelin in the CNS?
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What is the precursor of heme that is affected by a deficiency in PLP?
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What is the result of iron accumulation in erythroblasts in the bone marrow?
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What is the consequence of a vitamin B6 deficiency on homocysteine?
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What is the effect of isoniazid on vitamin B6?
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Why are people who take oral contraceptive pills advised to increase their vitamin B6 intake?
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What is the consequence of a deficiency in vitamin B6 on heme synthesis?
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What is the relationship between homocysteine and cardiovascular diseases?
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What is the function of vitamin B6 in cysteine synthesis?
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What is the role of folates in DNA synthesis?
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What is the result of combined deficiency of Vitamins B9 and B12?
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What happens to cells during folate deficiency?
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What is the characteristic of red blood cell precursors in macrocytic, megaloblastic anemia?
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Why do patients with macrocytic, megaloblastic anemia get anemia?
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What is the effect of folate deficiency on DNA synthesis?
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Which groups of people are at risk of folate deficiency due to impaired absorption?
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What is the effect of certain drugs on folate availability?
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Why may a person have a relative deficiency of folate during pregnancy?
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What is the mechanism of action of sulfonamides on bacteria?
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What is the effect of sulfonamides on bacterial growth?
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What is the function of trimethoprim?
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What is the effect of trimethoprim on bacterial growth?
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What is the combination of sulfamethoxazole and trimethoprim commonly used for?
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What is unique about the structure of cobalamin?
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Who is at risk for vitamin B12 deficiency?
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What is required for the conversion of homocysteine to methionine?
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What is the role of methionine in the synthesis of SAM?
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