Systemic Mycoses and Coccidioidomycosis
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Questions and Answers

What is the typical area of involvement for coccidioidomycosis?

  • Lungs (correct)
  • Intestines
  • Heart
  • Kidneys
  • Which of the following is true about the dissemination of coccidioidomycosis?

  • It is always fatal.
  • It primarily affects the skin.
  • It is usually self-limited. (correct)
  • It is highly communicable between individuals.
  • Which agent causes coccidioidomycosis?

  • Aspergillus flavus
  • C. immitis or C. posadasii (correct)
  • C. neoformans
  • Candida albicans
  • What type of morphology is observed in coccidioidomycosis cultures?

    <p>Hyphae with chains of arthroconidia</p> Signup and view all the answers

    Which of the following is NOT a common area of involvement for coccidioidomycosis?

    <p>Liver</p> Signup and view all the answers

    During which seasons is dust, a potential factor for coccidioidomycosis, most prevalent?

    <p>Summer and Autumn</p> Signup and view all the answers

    Which laboratory culture shows a white to tan cottony colony?

    <p>Sabouraud Dextrose Agar</p> Signup and view all the answers

    What is a correct statement regarding the communicability of coccidioidomycosis?

    <p>It is not communicable from person to person.</p> Signup and view all the answers

    What abbreviation stands for Grocott Methenamine Silver?

    <p>GMS</p> Signup and view all the answers

    Which of the following is a characteristic of coccidioidomycosis's hyphae?

    <p>Chains of arthroconidia</p> Signup and view all the answers

    What is another name for Coccidiomycosis?

    <p>Valley Fever</p> Signup and view all the answers

    Which organism causes Coccidiomycosis?

    <p>Coccidioides posadasii</p> Signup and view all the answers

    Where is Coccidiomycosis endemic?

    <p>Southwestern United States</p> Signup and view all the answers

    Which is a risk factor for systemic mycoses like Coccidiomycosis?

    <p>Travel history</p> Signup and view all the answers

    Which antifungal is classified as an Azole?

    <p>Fluconazole</p> Signup and view all the answers

    What distinguishes Coccidioides posadasii from Coccidioides immitis?

    <p>Their geographical location</p> Signup and view all the answers

    Which fungus is associated with opportunistic mycosis?

    <p>Aspergillus</p> Signup and view all the answers

    What is a characteristic of Pneumocystis Pneumonia?

    <p>It is often a complication of AIDS</p> Signup and view all the answers

    Which antifungal is known for targeting fungal cell membranes?

    <p>Amphotericin B</p> Signup and view all the answers

    Which of the following antifungal drugs is a topical treatment?

    <p>Terbinafine</p> Signup and view all the answers

    Study Notes

    Systemic Mycoses

    • Systemic mycoses are fungal infections that affect internal organs and systems.
    • Coccidioidomycosis is a systemic mycosis caused by the fungus Coccidioides immitis or Coccidioides posadasii.
    • Histoplasmosis is a systemic mycosis caused by the fungus Histoplasma capsulatum.
    • Blastomycosis is a systemic mycosis caused by the fungus Blastomyces dermatitidis.
    • Paracoccidioidomycosis is a systemic mycosis caused by the fungus Paracoccidioides brasiliensis.

    Coccidioidomycosis

    • Also known as "Valley Fever", "San Joaquin Valley Fever", or "Desert Rheumatism".
    • C. immitis and C. posadasii are phenotypically indistinguishable.
    • Endemic to Southwestern United States, Central America, and South America.
    • Important to consider travel history when diagnosing.
    • Higher infection rates during dry months of summer and autumn.
    • C. immitis is prevalent in California.
    • C. posadasii is prevalent in Arizona, Texas, and South America.
    • Usually self-limited.
    • Dissemination is rare, but always serious and fatal.
    • Not communicable from person to person.

    Coccidioidomycosis: Etiology, Morphology, and Area of Involvement

    • Caused by C. immitis or C. posadasii.
    • Primary area of involvement is the lungs.
    • Other areas of involvement: meninges, skin, subcutaneous tissue, bones, and joints.
    • Culture: White to tan cottony colony.
    • Hyphae: Chains of arthroconidia.

    Antifungal Chemotherapy

    • Amphotericin B is a common treatment option for systemic mycoses.
    • Flucytosine is another antifungal medication used to treat systemic fungal infections.
    • Azoles are a class of antifungal drugs used to treat various fungal infections.
    • Echinocandins are a class of antifungal medications that inhibit fungal cell wall synthesis.
    • Griseofulvin is an antifungal drug used to treat dermatophyte infections.
    • Terbinafine is an antifungal drug used to treat skin and nail fungal infections.
    • Topical antifungals are medications applied directly to the skin or mucous membranes to treat fungal infections.

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    Description

    Explore the fascinating world of systemic mycoses, focusing on infections caused by various fungi such as Coccidioides, Histoplasma, and Blastomyces. This quiz will test your knowledge on coccidioidomycosis, its causes, prevalence, and impact on health. Understand the patterns of infection and their geographic significance.

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