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Sulfasalazine Dosage and Administration Quiz
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Sulfasalazine Dosage and Administration Quiz

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Questions and Answers

What is the recommended dosage of the drug for maintenance of remission in ulcerative colitis and active Crohn's disease?

  • 500 mg twice a day
  • 500 mg four times a day (correct)
  • 250 mg four times a day
  • 1 g three times a day
  • Which condition requires an increased dosage of the drug to 2–3 g daily in divided doses?

  • Rheumatoid arthritis (correct)
  • Acute porphyrias
  • G6PD deficiency
  • Ulcerative colitis
  • What are the cautions mentioned in the text regarding the use of the drug?

  • Risk of seizure and vertigo
  • Risk of hepatic toxicity and risk of haematological toxicity (correct)
  • Maintaining adequate fluid intake and history of allergy
  • Risk of insomnia and stomatitis
  • Which side effect is specifically mentioned as occurring with urinary discoloration?

    <p>Urine abnormalities</p> Signup and view all the answers

    When do blood disorders typically occur with the drug?

    <p>In the first 3 to 6 months of treatment</p> Signup and view all the answers

    Which theoretical risks are considered for neonates in relation to the drug?

    <p>Neonatal haemolysis in the third trimester</p> Signup and view all the answers

    What does the manufacturer advise regarding the use of the drug with hepatic impairment?

    <p>Avoid in mild to moderate impairment</p> Signup and view all the answers

    Which monitoring requirements are mentioned for patients using the drug?

    <p>Monitoring full blood counts, renal function tests, and liver function tests at monthly intervals for the first three months</p> Signup and view all the answers

    What advice is given regarding contact lenses for patients using the drug?

    <p>Some soft contact lenses may be stained</p> Signup and view all the answers

    Which form of the drug is NOT available from special-order manufacturers?

    <p>Intravenous injection</p> Signup and view all the answers

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