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Sulfasalazine Dosage and Administration Quiz

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Sulfasalazine Dosage and Administration Quiz

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Questions and Answers

What is the recommended dosage of the drug for maintenance of remission in ulcerative colitis and active Crohn's disease?

500 mg twice a day

500 mg four times a day (correct)

250 mg four times a day

1 g three times a day

Which condition requires an increased dosage of the drug to 2–3 g daily in divided doses?

Rheumatoid arthritis (correct)

Acute porphyrias

G6PD deficiency

Ulcerative colitis

What are the cautions mentioned in the text regarding the use of the drug?

Risk of seizure and vertigo

Risk of hepatic toxicity and risk of haematological toxicity (correct)

Maintaining adequate fluid intake and history of allergy

Risk of insomnia and stomatitis

Which side effect is specifically mentioned as occurring with urinary discoloration?

Urine abnormalities Signup and view all the answers

When do blood disorders typically occur with the drug?

In the first 3 to 6 months of treatment Signup and view all the answers

Which theoretical risks are considered for neonates in relation to the drug?

Neonatal haemolysis in the third trimester Signup and view all the answers

What does the manufacturer advise regarding the use of the drug with hepatic impairment?

Avoid in mild to moderate impairment Signup and view all the answers

Which monitoring requirements are mentioned for patients using the drug?

Monitoring full blood counts, renal function tests, and liver function tests at monthly intervals for the first three months Signup and view all the answers

What advice is given regarding contact lenses for patients using the drug?

Some soft contact lenses may be stained Signup and view all the answers

Which form of the drug is NOT available from special-order manufacturers?

Intravenous injection Signup and view all the answers