18 Questions
What is the primary region affected by Ulcerative Colitis?
Large intestine
What is a common symptom of Ulcerative Colitis?
Rectal bleeding
What is a potential complication of Ulcerative Colitis due to malabsorption of water and electrolytes?
Dehydration and fatigue
What is the approximate percentage of patients with Ulcerative Colitis who remain symptom-free over a 10-year period?
Less than 5%
What is a potential extraintestinal manifestation of Ulcerative Colitis?
Arthritis
What is the approximate percentage of patients with Ulcerative Colitis who experience a relapse in any given year?
50%
What is a possible oral manifestation of toxic effects on bone marrow due to sulfasalazine use?
Bald tongue
Which of the following antibiotics is most commonly associated with an increased risk of pseudomembranous colitis?
Clindamycin
What is the most common presenting manifestation of pseudomembranous colitis?
Diarrhea
When is the highest risk of developing pseudomembranous colitis?
When antibiotics are used in hospitals or farmyards
What is the typical timing of diarrhea onset after antibiotic administration?
1-10 days after administration
What is a severe complication of pseudomembranous colitis?
Death
What is a complication of ulcerative colitis?
Adenocarcinoma of the colon
What is a characteristic of Crohn's disease?
Segmental distribution of intestinal ulcers
What is a feature of chronic Crohn's disease?
Nodular or 'cobblestone' appearance of the intestinal mucosa
What is a common initial manifestation of Crohn's disease?
Recurrent or persistent diarrhea
What is a complication of toxic megacolon?
Intestinal perforation
What is associated with Crohn's disease?
Noncaseating epithelioid granulomas
Learn about the toxic effects of sulfasalazine on bone marrow, including anemia, agranulocytosis, and thrombocytopenia. Also, understand the risks and symptoms of Pseudomembranous colitis, a severe form of colitis caused by Clostridium difficile overgrowth.
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