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Questions and Answers
Which of the following viral pathogens is commonly associated with respiratory tract infections and can be prevented through vaccination?
What is the primary mechanism of action for Oseltamivir in the treatment of viral respiratory infections?
When should antivirals be considered as a treatment option for viral respiratory infections?
Which of the following is a common symptomatic management option for treating cough in patients with viral respiratory infections?
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Which of these medications is used for the treatment of oral herpes simplex infections?
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Which of the following medications is primarily used for the management of Influenza?
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What is the mechanism of action of Oseltamivir?
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Which of the following viruses requires yearly vaccination due to high genetic diversity?
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Which supportive treatment is not commonly associated with the management of Respiratory Syncytial Virus (RSV) in children?
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Which of the following describes the structure of SARS-CoV-2?
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Which of the following is a typical symptom of Influenza?
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Which viral infection is characterized by the presence of antigenic drift and shift?
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Which component is not included in the symptomatic management for Respiratory Syncytial Virus?
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What is the primary function of increased mucous production during a viral respiratory tract infection?
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Which virus is associated with the barking cough known as croup?
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What is a common cause for respiratory tract infections in infants during the fall and winter?
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Which of the following viruses is primarily known for causing conjunctivitis in children?
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What symptom is NOT typically associated with respiratory tract viral infections?
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Which virus is commonly referred to as the primary cause of the common cold?
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What type of virus is the Respiratory Syncytial Virus (RSV)?
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What is the primary mode of transmission for adenovirus?
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Study Notes
Respiratory Tract Infections
- Most common pathogens: parainfluenza, RSV, influenza, COVID-19
- Pathophysiology: Viral entry into respiratory tract triggers inflammatory response, resulting in cytokine release, coughing, and airway sensitization. Increased mucus production attempts to remove foreign invaders, but inflammation can hinder clearance and trap mucus.
Viral RTI Presentation
- Signs and Symptoms: Cough, sneezing, rhinorrhea, sore throat, headache, malaise, fever
Parainfluenza
- Also known as croup
- Pathogen: Paramyxoviridae family, enveloped RNA virus
- Infects larynx, trachea, sometimes bronchi.
- Affects young children (ages 4-10)
- Clinical Presentation: "Barking" cough (seal-like), stridor, child usually appears non-toxic.
- Management: Symptomatic
Adenovirus
- Double stranded DNA virus, multiple serotypes
- Transmission: respiratory secretions, contact with contaminated objects, airborne, waterborne.
- Clinical presentation: Common cold symptoms (fever, pharyngitis, conjunctivitis, otitis media, cough, exudative tonsillitis, GI symptoms)
- Management: Symptomatic
Rhinovirus
- Characteristics: Single stranded RNA virus
- Causes common cold and asthma triggers
- Clinical presentation: Nasal dryness/irritation, sore throat, headache, cough, facial/ear pressure
- Management: Symptomatic
Respiratory Syncytial Virus (RSV)
- Pathogen: Single stranded RNA virus
- Transmission: Respiratory secretions
- Clinical Presentation: URTI symptoms, can cause pneumonia, bronchiolitis.
- Vaccination: For pregnant women, infants and elderly.
- Management for Children: Supportive, Glucocorticoids, Bronchodilators.
- Serious Cases: Ribavirin (nucleoside analog), IVIG, monoclonal antibodies (Palivizumab, Nirsevimab)
Influenza
- Types A and B most common in US
- Clinical presentation: Fever, nonproductive cough, myalgia, malaise, sore throat, nausea, nasal congestion, and headache.
- Pathophysiology: High genetic diversity through antigenic drift and shift, leading to the need for annual vaccination.
- Management: Oseltamivir (Tamiflu)
COVID-19 (SARS-CoV-2)
- Pathogen: Coronavirus, enveloped positive sense, single stranded RNA virus.
- Clinical Presentation: URTI symptoms, can cause lower respiratory tract infection, pneumonia, and pulmonary symptoms.
- Pathophysiology: High genetic variation requires annual vaccination.
Viral Vaccination
- Available for: COVID-19, Influenza, RSV, Varicella (Chickenpox), Shingles, Monkeypox, Hib (Haemophilus influenzae type b), Hepatitis A & B, HPV (Human Papilloma Virus)
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Description
This quiz covers the main pathogens associated with respiratory tract infections, including parainfluenza, RSV, influenza, and COVID-19. It explores the pathophysiology, clinical presentation, and management of these infections, with a focus on symptoms and viral characteristics. Test your knowledge on the signs, symptoms, and treatment options for viral respiratory tract infections.