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Questions and Answers
What happens to the pressure inside the thoracic cavity during inspiration?
What happens to the pressure inside the thoracic cavity during inspiration?
Expiration is primarily an active process that requires muscle contraction.
Expiration is primarily an active process that requires muscle contraction.
False
Name the primary muscle responsible for inspiration.
Name the primary muscle responsible for inspiration.
Diaphragm
During expiration, the diaphragm returns to its ______ shape.
During expiration, the diaphragm returns to its ______ shape.
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Match the following muscle functions to their respective phases of pulmonary ventilation:
Match the following muscle functions to their respective phases of pulmonary ventilation:
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Which accessory muscles assist in more forceful inspiration during exercise?
Which accessory muscles assist in more forceful inspiration during exercise?
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Pulmonary ventilation involves both inhalation and exhalation.
Pulmonary ventilation involves both inhalation and exhalation.
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What is the effect of increased thoracic cavity volume on gas movement?
What is the effect of increased thoracic cavity volume on gas movement?
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What is the formula for Functional Residual Capacity (FRC)?
What is the formula for Functional Residual Capacity (FRC)?
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Inspiratory Capacity (IC) is the maximum volume of air that can be inspired from the end of a normal expiration.
Inspiratory Capacity (IC) is the maximum volume of air that can be inspired from the end of a normal expiration.
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Describe Boyle's law in relation to the respiratory system.
Describe Boyle's law in relation to the respiratory system.
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The atmosphere is composed of ___% nitrogen.
The atmosphere is composed of ___% nitrogen.
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Match the gas laws with their descriptions:
Match the gas laws with their descriptions:
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Which gas is found in the atmosphere at approximately 0.04%?
Which gas is found in the atmosphere at approximately 0.04%?
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Gas will always move from a region of low pressure to a region of high pressure.
Gas will always move from a region of low pressure to a region of high pressure.
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The maximum volume of air that can be inspired from the end of a normal expiration is known as ___ capacity.
The maximum volume of air that can be inspired from the end of a normal expiration is known as ___ capacity.
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What is the normal tidal volume (TV) for a healthy adult?
What is the normal tidal volume (TV) for a healthy adult?
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The total lung capacity (TLC) is equal to the sum of all basic lung volumes excluding residual volume (RV).
The total lung capacity (TLC) is equal to the sum of all basic lung volumes excluding residual volume (RV).
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What is the function of the inspiratory reserve volume (IRV)?
What is the function of the inspiratory reserve volume (IRV)?
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The maximum volume of air that can be expired following a maximal inspiration is known as __________.
The maximum volume of air that can be expired following a maximal inspiration is known as __________.
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Match the lung volume/capacity with its description:
Match the lung volume/capacity with its description:
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During normal breathing at rest, approximately what fraction of total lung capacity is commonly used?
During normal breathing at rest, approximately what fraction of total lung capacity is commonly used?
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Vital capacity includes tidal volume (TV), inspiratory reserve volume (IRV), and expiratory reserve volume (ERV).
Vital capacity includes tidal volume (TV), inspiratory reserve volume (IRV), and expiratory reserve volume (ERV).
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The total lung capacity formula is __________ = RV + IRV + TV + ERV.
The total lung capacity formula is __________ = RV + IRV + TV + ERV.
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What is the primary function of pulmonary respiration?
What is the primary function of pulmonary respiration?
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Tissue respiration is also called external respiration.
Tissue respiration is also called external respiration.
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What is the term for the combination of hemoglobin and oxygen?
What is the term for the combination of hemoglobin and oxygen?
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Blood transport gases between the lungs and body __________.
Blood transport gases between the lungs and body __________.
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Which factor does NOT influence the release of oxygen by hemoglobin?
Which factor does NOT influence the release of oxygen by hemoglobin?
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Match the following terms with their definitions:
Match the following terms with their definitions:
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The majority of oxygen transported in the blood is dissolved in plasma.
The majority of oxygen transported in the blood is dissolved in plasma.
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What happens to hemoglobin when the partial pressure of oxygen is low?
What happens to hemoglobin when the partial pressure of oxygen is low?
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What percentage of carbon dioxide is transported in the blood as bicarbonate?
What percentage of carbon dioxide is transported in the blood as bicarbonate?
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Lactic acid promotes the release of oxygen from hemoglobin during exercise.
Lactic acid promotes the release of oxygen from hemoglobin during exercise.
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What enzyme catalyzes the conversion of carbon dioxide and water to carbonic acid in red blood cells?
What enzyme catalyzes the conversion of carbon dioxide and water to carbonic acid in red blood cells?
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At the lungs, bicarbonate ions move into the RBCs and bind with __________ ions to form carbonic acid.
At the lungs, bicarbonate ions move into the RBCs and bind with __________ ions to form carbonic acid.
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Match the following terms with their corresponding descriptions:
Match the following terms with their corresponding descriptions:
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Which of the following factors increases the release of oxygen from hemoglobin?
Which of the following factors increases the release of oxygen from hemoglobin?
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During exercise, tissues produce less heat which decreases local temperature.
During exercise, tissues produce less heat which decreases local temperature.
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What are the two types of motor control of breathing?
What are the two types of motor control of breathing?
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What is the primary function of the inspiratory center?
What is the primary function of the inspiratory center?
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Exhalation is primarily an active process requiring muscle contraction.
Exhalation is primarily an active process requiring muscle contraction.
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What are the two main groups of neurons involved in controlling respiration in the brainstem?
What are the two main groups of neurons involved in controlling respiration in the brainstem?
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The __________ center in the pons increases the depth and duration of inspiration.
The __________ center in the pons increases the depth and duration of inspiration.
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Match the respiratory centers with their functions:
Match the respiratory centers with their functions:
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Which reflex promotes constriction of air passages in response to irritants?
Which reflex promotes constriction of air passages in response to irritants?
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The rate of respiration is determined by how long the expiratory center is active.
The rate of respiration is determined by how long the expiratory center is active.
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What role do stretch receptors in the lungs play in respiration?
What role do stretch receptors in the lungs play in respiration?
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Changes in arterial _________ can modify respiratory rate even when CO2 and O2 levels are stable.
Changes in arterial _________ can modify respiratory rate even when CO2 and O2 levels are stable.
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What happens during hyperventilation?
What happens during hyperventilation?
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The pontine respiratory group participates in voluntary control of breathing.
The pontine respiratory group participates in voluntary control of breathing.
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What limits the inspiration from being too deep?
What limits the inspiration from being too deep?
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Substantial drops in arterial PO2 to _________ mm Hg become critical for increasing ventilation.
Substantial drops in arterial PO2 to _________ mm Hg become critical for increasing ventilation.
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Match the following responses with their triggers:
Match the following responses with their triggers:
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Study Notes
Learning Outcomes
- Students should be able to describe lung volumes and capacities of the respiratory system.
- Students should be able to explain pulmonary ventilation in the respiratory system.
- Students should be able to explain external and internal respiration.
- Students should be able to describe the transport of respiratory gases.
- Students should be able to explain the control of respiration.
Lung Volumes and Capacities
- A healthy adult breathes about 12 times per minute, with each breath moving about 500 mL of air in and out of the lungs.
- Measuring lung volumes helps understand normal lung function and disease states.
- At rest, about one-tenth of the total lung capacity is used; greater amounts are used with exercise.
Lung Volumes and Capacities (terms)
- Tidal volume (TV): The amount of gas inspired or expired with each normal breath, about 500 mL.
- Inspiratory reserve volume (IRV): Maximum amount of additional air that can be inspired from the end of normal inspiration.
- Expiratory reserve volume (ERV): Maximum volume of additional air that can be expired from the end of a normal expiration.
- Residual volume (RV): Volume of air remaining in the lung after maximal expiration.
- Total lung capacity (TLC): Volume of air contained in the lungs at the end of a maximal inspiration. TLC = RV + IRV + TV + ERV.
- Vital capacity (VC): Maximum volume of air that can be forcefully expelled from the lungs following a maximal inspiration. VC = IRV + TV + ERV.
- Functional residual capacity (FRC): Volume of air remaining in the lung at the end of a normal expiration. FRC = RV + ERV.
- Inspiratory capacity (IC): Maximum volume of air that can be inspired from end expiratory position. IC = TV + IRV.
Understanding Gases
- The atmosphere is composed of nitrogen (78%), oxygen (21%), carbon dioxide (0.04%), and water vapor (variable, around 1%).
- Gases obey gas laws, which apply equally to gases in the atmosphere, lungs, blood, and cells.
Boyle's Law
- Boyle's law discusses how volume and pressure are inversely related in containers with flexible walls, such as the thoracic cage.
- If the volume decreases, pressure increases, and vice versa.
Henry's Law
- The quantity of gas dissolving in a liquid is proportional to the partial pressure of the gas and its solubility.
Charles' Law
- As temperature rises, pressure increases; as temperature falls, pressure decreases.
Dalton's Law
- Each gas in a mixture of gases exerts its own pressure as if no other gases were present.
Gas Exchange
- Gas molecules diffuse from higher pressure (concentration) regions to lower pressure (concentration) regions.
Pulmonary Ventilation
- Pulmonary ventilation is the movement of air between the atmosphere and alveoli, achieved by changes in intrathoracic volume.
- Breathing has two phases: inspiration (inhaling) and expiration (exhaling).
Inspiration/Inhalation
- External intercostal muscles contract.
- Diaphragm contracts (downward and flattens).
- Rib cage moves up and out.
- Thoracic cavity increases in size.
- Pressure inside thoracic cavity decreases.
- Air moves from higher pressure (atmosphere) to lower pressure (lungs).
Expiration/Exhalation
- External intercostal and abdominal muscles relax.
- Rib cage moves down and in.
- Diaphragm relaxes (returns to dome shape).
- Thoracic cavity decreases in size.
- Pressure inside thoracic cavity increases.
- Air moves from higher pressure (lungs) to lower pressure (atmosphere).
Pulmonary Respiration
- External respiration: Exchange of oxygen (O2) and carbon dioxide (CO2) between the alveoli and pulmonary blood capillaries.
- Deoxygenated blood becomes oxygenated.
Tissue Respiration
- Internal respiration: Exchange of oxygen and carbon dioxide between blood in capillaries and body cells.
- Oxygenated blood delivers O2 to tissues; receives CO2 from tissues.
Transport of Respiratory Gases
- Blood transports gases between the lungs and body tissues.
- Oxygen and carbon dioxide undergo physical and chemical changes during transport and exchange.
Oxygen Transport
- Oxygen is bound to hemoglobin (98.5%) within red blood cells, and dissolved in plasma (1.5%).
- Hemoglobin binds O2 readily when blood partial pressure of O2 (PO2) is high, and releases O2 when PO2 is low.
- Other factors influencing oxygen release include PCO2, acidity, and temperature.
Carbon Dioxide Transport
- Carbon dioxide is transported in three forms: dissolved in plasma, chemically bound to hemoglobin (carbaminohemoglobin), and as bicarbonate ions.
Control of Respiration
- Breathing is controlled voluntarily and involuntarily.
- Voluntary control is via somatic motor neurons in the medulla oblongata and pons.
- Involuntary control is via feedback from receptors monitoring blood chemistry.
- Control centers in the medulla and pons include the dorsal respiratory group (DRG), ventral respiratory group (VRG), and pontine respiratory group (PRG).
- The respiratory rhythm can also be influenced by intrinsic properties of inspiratory neurons, stretch receptors in the lungs, and other stimuli like emotions, pain, and temperature.
- Rate and depth of breathing are influenced by PCO2, PO2, and pH levels in the blood and cerebrospinal fluid.
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Description
This quiz covers key concepts about lung volumes and capacities, pulmonary ventilation, and the processes of external and internal respiration. Students will learn the transport mechanisms of respiratory gases and control of breathing. Aimed at providing a comprehensive understanding of the respiratory system.