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Questions and Answers
What happens to the intra-alveolar pressure during inspiration?
At the end of expiration, what is the relationship between intra-alveolar pressure and atmospheric pressure?
What occurs when thoracic volume increases during inspiration?
Which pressure measurement is recorded as 759 mm Hg during inspiration?
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During expiration, what happens to the pressure inside the alveoli?
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What type of epithelium lines the inner surface of the trachea?
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What role does the mucus serve in the trachea?
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What is the atmospheric pressure considered during this process?
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Which muscle contracts during coughing in the trachea?
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What is the state of air movement at the end of expiration?
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How does the structure of the trachea facilitate the removal of mucus?
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Which phase of breathing involves the contraction of the diaphragm?
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What comprises the posterior surface of the trachea?
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Which feature indicates that the trachea is effective in trapping foreign particles?
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What is the primary function of the tracheobronchial tree?
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What happens to mucus in the trachea when cilia move?
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What primary effect does hypercapnia have on respiration?
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Which area of the brain is primarily responsible for regulating CO2 and pH levels?
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What adjustment occurs because of a decrease in oxygen levels (hypoxia)?
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What characterizes the anaerobic threshold during exercise?
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How do carotid and aortic body chemoreceptors respond to changes in blood pH?
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What is the primary function of alveolar ventilation (VA)?
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Which of the following best describes the process of inspiration?
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Which zone is responsible for pulmonary gas exchange?
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What physiological mechanism is primarily involved in altering blood pH?
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Which component of the tracheobronchial tree helps keep the airway open?
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How do the amounts of cartilage and smooth muscle change as the bronchioles become smaller?
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Which type of epithelium lines the larger bronchioles?
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What is the function of ACE in the respiratory system?
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What is the average PO2 of alveolar air?
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At what pressure does oxygen diffuse into the pulmonary capillaries?
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What is the PO2 of arterial blood as it arrives in the tissues?
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Why does the PO2 decrease slightly in the pulmonary veins?
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What is the average PCO2 of arterial blood arriving in the tissues?
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What happens to oxygen when blood reaches the venous end of a capillary network?
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How is carbon dioxide transported from cells to blood?
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What is the PO2 in individual tissue cells?
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Study Notes
Trachea
- The trachea is a tube that connects the larynx to the bronchi
- The posterior surface is elastic and is composed of a ligamentous membrane and smooth muscle called the trachealis muscle
- The trachealis muscle contracts during coughing
- The inner lining is composed of pseudostratified ciliated columnar epithelium with goblet cells
- Mucus traps debris and cilia push it superiorly to the larynx and pharynx
Tracheobronchial Tree
- The tracheobronchial tree is made up of the trachea and the branching network of air tubes in the lungs
- The trachea to the terminal bronchioles is ciliated, to remove debris
- Cartilage holds the airways open
- Smooth muscle controls the diameter of the airways
- The amount of cartilage decreases as the tubes get smaller and the amount of smooth muscle increases
Lobar Bronchi
- Lobar bronchi arise from the main bronchi
- Each lobar bronchus serves a lobe of the lungs
- Lobar bronchi contain cartilage plates
- They are lined with pseudostratified ciliated columnar epithelium
- There are three lobar bronchi on the right and two on the left
Segmental Bronchi
- Segmental bronchi supply bronchopulmonary segments
Bronchioles
- Bronchioles are less than 1 mm in diameter
- Larger bronchioles are lined with ciliated simple columnar epithelium
Gas Exchange: Oxygen
- The partial pressure of oxygen (PO2) of alveolar air is approximately 104 mmHg
- PO2 in the pulmonary capillaries is approximately 40 mmHg
- Oxygen diffuses into the pulmonary capillaries, down its partial pressure gradient
- The PO2 in blood reaches an equilibrium of 104 mmHg by the time it reaches the venous ends of the pulmonary capillaries, even during exercise
- There is a slight decrease in the PO2 of blood in the pulmonary veins to about 95 mmHg, due to mixing of deoxygenated blood from the bronchial veins with blood leaving the pulmonary capillaries
- The PO2 of arterial blood as it arrives in the tissues is still 95 mmHg compared to the PO2 of the interstitial fluid, which is 40 mmHg
- Oxygen diffuses out of the capillaries into the interstitial fluid and across the plasma membrane of individual cells
- The PO2 in individual tissue cells is around 20 mmHg and the cells use the O2 for cellular respiration
- By the time blood has reached the venous end of a capillary network, it has achieved an equilibrium with the cells and interstitial fluid
Gas Exchange: Carbon Dioxide
- As cells produce CO2, the intracellular PCO2 increases to approximately 46 mmHg and the interstitial fluid PCO2 is approximately 45 mmHg
- The PCO2 of arterial blood as it arrives in the tissues is 40 mmHg
- CO2 diffuses out of the cells, into the interstitial fluid and into the blood, down its partial pressure gradient
Chemical Control of Ventilation
- Carbon Dioxide: A small change in carbon dioxide in the blood triggers a large increase in the rate and depth of respiration
- Hypercapnia is greater-than-normal amount of carbon dioxide, increases breathing rate
- Hypocapnia is lower-than-normal amount of carbon dioxide, decreases breathing rate
- The chemosensitive area in medulla oblongata is more important for regulation of CO2 and pH
- Carotid bodies respond rapidly to changes in blood pH, brought on by exercise
- Oxygen: Carotid and aortic body chemoreceptors respond to decreased O2 by increased stimulation of the respiratory center to keep it active despite decreasing oxygen levels
- Hypoxia is a decrease in oxygen levels below normal values
Effect of Exercise on Ventilation
- Ventilation increases abruptly at the onset of exercise
- The movement of limbs has a strong influence on ventilation
- There is a learned component of ventilation during exercise
- After the immediate increase, ventilation increases gradually over a period of 4-6 minutes
- The anaerobic threshold refers to the highest level of exercise without causing a significant change in blood pH
- If the anaerobic threshold is exceeded, lactic acid is produced by skeletal muscles
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Description
Test your knowledge on the anatomy of the trachea and tracheobronchial tree. This quiz covers their structure, function, and the role of cilia and smooth muscle in the respiratory system. Perfect for students studying respiratory anatomy in biology.