Podcast
Questions and Answers
What is the primary purpose of inflammation in the body?
What is the primary purpose of inflammation in the body?
- To inactivate or destroy invading organisms (correct)
- To produce autoantibodies
- To activate the immune system
- To cause tissue injury
In rheumatoid arthritis (RA), which cells initiate the inflammatory attack?
In rheumatoid arthritis (RA), which cells initiate the inflammatory attack?
- B lymphocytes
- T lymphocytes (correct)
- Monocytes
- Macrophages
Which of the following cytokines is secreted into the synovial cavity in rheumatoid arthritis?
Which of the following cytokines is secreted into the synovial cavity in rheumatoid arthritis?
- Interleukin-6 (IL-6)
- Tumor necrosis factor (TNF)-a (correct)
- Granulocyte-macrophage colony-stimulating factor (GM-CSF)
- Interferon-gamma (IFN-γ)
What is the role of B lymphocytes in rheumatoid arthritis?
What is the role of B lymphocytes in rheumatoid arthritis?
What are the goals of pharmacotherapy for rheumatoid arthritis?
What are the goals of pharmacotherapy for rheumatoid arthritis?
What are the consequences of inappropriate activation of the immune system?
What are the consequences of inappropriate activation of the immune system?
Which enzyme is responsible for the physiologic production of prostanoids?
Which enzyme is responsible for the physiologic production of prostanoids?
What is the primary precursor of the prostaglandins and related compounds?
What is the primary precursor of the prostaglandins and related compounds?
Which type of acids are related to thromboxanes, leukotrienes, HPETEs, and HETEs?
Which type of acids are related to thromboxanes, leukotrienes, HPETEs, and HETEs?
What is the primary function of prostaglandins in the gastrointestinal (GI) tract?
What is the primary function of prostaglandins in the gastrointestinal (GI) tract?
Which pathway is responsible for the synthesis of all eicosanoids with 3 ring structures?
Which pathway is responsible for the synthesis of all eicosanoids with 3 ring structures?
Which type of drugs act by inhibiting the cyclooxygenase enzymes that catalyze the first step in prostanoid biosynthesis?
Which type of drugs act by inhibiting the cyclooxygenase enzymes that catalyze the first step in prostanoid biosynthesis?
Which enzyme causes the elevated production of prostanoids that occurs in sites of disease and inflammation?
Which enzyme causes the elevated production of prostanoids that occurs in sites of disease and inflammation?
'All NSAIDs act by inhibiting the cyclooxygenase enzymes' - This statement is:
'All NSAIDs act by inhibiting the cyclooxygenase enzymes' - This statement is:
'Thromboxanes, leukotrienes, HPETEs, and HETEs are related lipids synthesized from different precursors than prostaglandins' - This statement is:
'Thromboxanes, leukotrienes, HPETEs, and HETEs are related lipids synthesized from different precursors than prostaglandins' - This statement is:
What is the primary precursor of eicosanoids?
What is the primary precursor of eicosanoids?
