Podcast
Questions and Answers
What is the primary purpose of inflammation in the body?
What is the primary purpose of inflammation in the body?
- To remove irritants (correct)
- To stimulate T lymphocytes
- To initiate an immune response
- To destroy invading organisms
Which type of cells initiate an inflammatory attack in rheumatoid arthritis (RA)?
Which type of cells initiate an inflammatory attack in rheumatoid arthritis (RA)?
- White blood cells (WBCs) (correct)
- Platelets
- Lymphocytes
- Red blood cells (RBCs)
What do monocytes and macrophages secrete into the synovial cavity in RA?
What do monocytes and macrophages secrete into the synovial cavity in RA?
- Proinflammatory cytokines (correct)
- Hormones
- Anti-inflammatory cytokines
- Growth factors
Which cells produce rheumatoid factor and other autoantibodies in RA?
Which cells produce rheumatoid factor and other autoantibodies in RA?
What is the primary goal of pharmacotherapy for rheumatoid arthritis (RA)?
What is the primary goal of pharmacotherapy for rheumatoid arthritis (RA)?
Inappropriate activation of the immune system can result in inflammation and immunemediated diseases such as:
Inappropriate activation of the immune system can result in inflammation and immunemediated diseases such as:
What is the primary precursor of prostaglandins and related compounds?
What is the primary precursor of prostaglandins and related compounds?
Which enzyme is responsible for the physiologic production of prostanoids?
Which enzyme is responsible for the physiologic production of prostanoids?
Where is Cyclooxygenase-2 (COX-2) constitutively expressed?
Where is Cyclooxygenase-2 (COX-2) constitutively expressed?
What function in the body do prostaglandins control?
What function in the body do prostaglandins control?
What is the primary action of non-steroidal anti-inflammatory drugs (NSAIDs)?
What is the primary action of non-steroidal anti-inflammatory drugs (NSAIDs)?
Which compound is synthesized via the cyclooxygenase pathway?
Which compound is synthesized via the cyclooxygenase pathway?
Which pathway forms leukotrienes or lipoxins depending on the tissue?
Which pathway forms leukotrienes or lipoxins depending on the tissue?
What do all non-steroidal anti-inflammatory drugs (NSAIDs) share in terms of therapeutic actions and adverse effects?
What do all non-steroidal anti-inflammatory drugs (NSAIDs) share in terms of therapeutic actions and adverse effects?
