Podcast
Questions and Answers
Which of the following criteria would NOT prompt pharmacological treatment for osteoporosis?
Which of the following criteria would NOT prompt pharmacological treatment for osteoporosis?
- Low bone mineral density (T-score between -1.0 and -2.5)
- 10-year probability of a hip fracture ≥3%
- T-score of -2.0 at the femoral neck (correct)
- Fragility fracture of the hip
How do most osteoporosis medications work?
How do most osteoporosis medications work?
- By reducing the bone-building process
- By accelerating bone breakdown
- By inhibiting osteoclastic bone resorption (correct)
- By inhibiting osteoblastic bone formation
What is the primary mechanism of action of antiresorptive medications?
What is the primary mechanism of action of antiresorptive medications?
- Reducing bone density
- Inhibiting osteoclastic bone resorption (correct)
- Stimulating osteoblastic bone formation
- Accelerating the bone-building process
Which medication is considered the most cost-effective option and is often the first-line agent used for osteoporosis treatment?
Which medication is considered the most cost-effective option and is often the first-line agent used for osteoporosis treatment?
How are oral bisphosphonates typically administered?
How are oral bisphosphonates typically administered?
Which type of medication primarily stimulates osteoblastic bone formation?
Which type of medication primarily stimulates osteoblastic bone formation?
What is the main reason oral bisphosphonates should be taken on an empty stomach?
What is the main reason oral bisphosphonates should be taken on an empty stomach?
Which medication primarily inhibits osteoclastic bone resorption?
Which medication primarily inhibits osteoclastic bone resorption?
What is the purpose of anabolic drugs in osteoporosis treatment?
What is the purpose of anabolic drugs in osteoporosis treatment?
Which type of medication has variable effects on bone resorption?
Which type of medication has variable effects on bone resorption?
What is the mode of administration for intravenous bisphosphonate preparations like zoledronate?
What is the mode of administration for intravenous bisphosphonate preparations like zoledronate?
What condition would prompt pharmacological treatment for osteoporosis according to the given criteria?
What condition would prompt pharmacological treatment for osteoporosis according to the given criteria?
Study Notes
Osteoporosis Treatment
- A T-score of -2.5 or lower in the absence of a fracture would prompt pharmacological treatment for osteoporosis.
- Most osteoporosis medications work by either inhibiting bone resorption or stimulating bone formation.
- Antiresorptive medications primarily work by inhibiting osteoclastic bone resorption.
- Alendronate is considered the most cost-effective option and is often the first-line agent used for osteoporosis treatment.
- Oral bisphosphonates are typically administered weekly or monthly.
- Anabolic medications, such as teriparatide, primarily stimulate osteoblastic bone formation.
- Oral bisphosphonates should be taken on an empty stomach to enhance absorption and reduce gastrointestinal side effects.
- Bisphosphonates primarily inhibit osteoclastic bone resorption.
- Anabolic drugs are used to stimulate bone formation and increase bone mineral density in osteoporosis treatment.
- Hormone replacement therapy has variable effects on bone resorption.
- Intravenous bisphosphonate preparations like zoledronate are administered via a 15-minute infusion once a year.
Studying That Suits You
Use AI to generate personalized quizzes and flashcards to suit your learning preferences.
Description
Test your knowledge of the criteria for pharmacological treatment for osteoporosis in postmenopausal women and men aged 50 years and over. Learn about the indications for treatment based on fragility fractures, DXA T-scores, low bone mineral density, and fracture probabilities.
