Pharmacological Management of Osteoporosis Quiz

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Questions and Answers

What is the maximum number of times teriparatide can be used?

Once in a lifetime (correct)

Three times in a lifetime

Four times in a lifetime

Twice in a lifetime

What happens if denosumab is stopped suddenly?

No effect on bone density

Decrease in bone density (correct)

No information regarding bone density changes

Increase in bone density

What is the favored treatment for patients with chronic kidney disease (CKD)?

Teriparatide

Calcium and vitamin D supplementation

Bisphosphonates

Denosumab (correct)

In which condition should teriparatide not be prescribed?

Increased basal risk for osteosarcoma Signup and view all the answers

What patient factor may make it difficult for individuals to remember to take weekly oral bisphosphonates or daily subcutaneous teriparatide?

Cognitive difficulties Signup and view all the answers

What is the risk associated with a fragility fracture while on osteoporosis treatment?

Drop in bone density Signup and view all the answers

What is the reason for advising Katiana to take the medication on an empty stomach first thing in the morning?

To reduce the risk of esophageal reflux Signup and view all the answers

Why is it suggested that Katiana should undergo an x-ray?

To rule out a fracture Signup and view all the answers

What lifestyle change is recommended for Katiana?

A short walk daily accompanied by her caregiver Signup and view all the answers

What will be possible with the new prognostic and therapeutic strategies being developed?

Precise prediction of fracture risk Signup and view all the answers

What is the potential impact of novel developments on fracture risk assessment?

More precise identification of patients at high risk of fracture Signup and view all the answers

Why should the future use of oral steroids be limited for Katiana?

To decrease the falls risk associated with osteoporosis Signup and view all the answers

What is a key focus of Katiana's COPD regimen review?

Assessing her inhaler technique Signup and view all the answers

Why is Katiana referred for a multifactorial falls risk assessment?

Because she is at risk of falls Signup and view all the answers

What is the projected trend for the number of people living with osteoporosis?

Increase dramatically over the next decade Signup and view all the answers

Study Notes

Osteoporosis Treatment and Management

Teriparatide should not be reused after a drug holiday.
Stopping denosumab suddenly can lead to rebound vertebral fracture.
In patients with chronic kidney disease (CKD), the favored treatment is oral bisphosphonates.
Teriparatide is contraindicated in patients with hypercalcemia.
Cognitive impairment is a patient factor that can affect adherence to weekly oral bisphosphonates or daily subcutaneous teriparatide.

Medication Administration and Lifestyle Changes

Teriparatide should be taken on an empty stomach first thing in the morning to enhance absorption.
An x-ray is suggested to monitor bone density and detect potential fractures.
Regular exercise is recommended to improve bone health and reduce fracture risk.
Quitting smoking is also recommended to prevent bone loss.

Future Directions and Prognosis

Emerging therapeutic strategies may enable personalized fracture risk assessment and treatment.
Novel developments may improve fracture risk assessment and prediction.
Limiting future use of oral steroids can reduce osteoporosis risk in Katiana.
Katiana's COPD regimen review should focus on the safe use of inhaled corticosteroids.

Falls Risk Assessment and Osteoporosis Prevalence

Katiana is referred for a multifactorial falls risk assessment to identify and address potential fall risk factors.
The global prevalence of osteoporosis is projected to increase due to the aging population.

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Description

Test your knowledge on the pharmacological care of osteoporosis patients, including long-term management strategies and important considerations during changes in drug treatment. Explore topics such as timing of teriparatide use, the impact of sudden denosumab cessation, and response to fragility fractures while on treatment.