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PHAR 5228: Pharmacology of Drugs Related to Reproductive Processes Quiz

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PHAR 5228: Pharmacology of Drugs Related to Reproductive Processes Quiz

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Questions and Answers

What is the enzyme responsible for synthesizing estrogens from androgens in the female reproductive system?

GnRH

Aromatase (correct)

hCG

Which hormone stimulates the production of estrogens by acting on granulosa cells?

FSH (correct)

Progesterone

hCG

What causes a surge of LH release at midcycle?

Increase in FSH levels

Increase in estrogen levels (correct)

Increase in progesterone levels

Decrease in estradiol levels

What effect does progesterone have on the frequency of GnRH release?

Decreases it Signup and view all the answers

Which estrogen receptor is highly expressed in the female reproductive tract and mammary gland?

ERα Signup and view all the answers

What is the mechanism of action of Tamoxifen in treating hormone-receptor positive breast cancers?

Block estrogen receptors Signup and view all the answers

Which compound inhibits the enzyme aromatase to prevent the conversion of androgens to estrogens?

Aromatase inhibitors Signup and view all the answers

What is the function of progesterone receptors (PRs) when bound to progesterone?

Induce dimerization and DNA binding Signup and view all the answers

What is the purpose of ulipristal acetate in fertility treatment?

Act as a PR antagonist Signup and view all the answers

What is the function of Gonadotropin-Releasing Hormone (GnRH) in 'Ovarian Hyper-Stimulation' protocols for fertility treatment?

Shorten cycle duration Signup and view all the answers