12 Questions
What is the main function of the immune system?
To recognize and protect against infections
Who is often attributed as the Father of Immunology?
Louis Pasteur
What are the two main lineages derived from hematopoietic stem cells in the immune system?
Myeloid and lymphoid lineages
What led to the discovery of protection against human smallpox?
Discovery of cowpox-induced protection
Where are hematopoietic stem cells (HSCs) found in adults?
In the bone marrow
Which cells are included in the myeloid cell lineage?
Monocytes, macrophages, neutrophils, and dendritic cells
Which cells are part of the adaptive immune system?
T cells, B cells, and natural killer cells
What is the origin of macrophages?
Blood monocytes that leave the circulation to differentiate in different tissues
What is the function of alveolar macrophages?
Initiation and control of immunity to respiratory pathogens
What type of macrophages are found in the liver?
Kupffer cells
What do macrophages use to detect products of bacteria and other microorganisms?
Recognition receptors such as Toll-like receptors (TLRs)
What is the role of MBL and CRP plasma proteins?
Binding specifically to different pathogen components like sugars (LPS), RNA, DNA, or extracellular proteins
Test your understanding of Immunology Chapter 1 with topics including WBCs development, differences between innate and adaptive immunity, differences between granulocytes and agranulocytes, line of defenses, and macrophages.
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