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PHAR 308 Immunology Chapter 1 Learning Outcomes

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PHAR 308 Immunology Chapter 1 Learning Outcomes

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Questions and Answers

What is the main function of the immune system?

To produce red blood cells

To develop hematopoietic stem cells

To recognize and protect against infections (correct)

To induce protection against smallpox

Who is often attributed as the Father of Immunology?

Hematopoietic stem cells

Louis Pasteur (correct)

Edward Jenner

Maryam AlRamadan

What are the two main lineages derived from hematopoietic stem cells in the immune system?

Red blood cells and white blood cells

Cowpox and smallpox

Myeloid and lymphoid lineages (correct)

Granulocytes and agranulocytes

What led to the discovery of protection against human smallpox?

Discovery of cowpox-induced protection Signup and view all the answers

Where are hematopoietic stem cells (HSCs) found in adults?

In the bone marrow Signup and view all the answers

Which cells are included in the myeloid cell lineage?

Monocytes, macrophages, neutrophils, and dendritic cells Signup and view all the answers

Which cells are part of the adaptive immune system?

T cells, B cells, and natural killer cells Signup and view all the answers

What is the origin of macrophages?

Blood monocytes that leave the circulation to differentiate in different tissues Signup and view all the answers

What is the function of alveolar macrophages?

Initiation and control of immunity to respiratory pathogens Signup and view all the answers

What type of macrophages are found in the liver?

Kupffer cells Signup and view all the answers

What do macrophages use to detect products of bacteria and other microorganisms?

Recognition receptors such as Toll-like receptors (TLRs) Signup and view all the answers

What is the role of MBL and CRP plasma proteins?

Binding specifically to different pathogen components like sugars (LPS), RNA, DNA, or extracellular proteins Signup and view all the answers