5 Questions
What are the two main causes of peptic ulcer disease?
Infection with gram-negative Helicobacter pylori and the use of nonsteroidal anti-inflammatory drugs (NSAIDs)
How is infection with H. Pylori diagnosed?
Via endoscopic biopsy of the gastric mucosa or various noninvasive methods
What is the recommended first-line treatment for patients with peptic ulcer disease infected with H. Pylori?
Quadruple therapy of bismuth subsalicylate, metronidazole, and tetracycline plus a PPI
What are the treatment options for reducing secretion of gastric acid?
PPis and sucralfate
What is a preferred treatment for patients infected with H. Pylori when rates of clarithromycin resistance are low?
Triple therapy with a PPI, amoxicillin, and clarithromycin
Test your knowledge about the treatment approaches for peptic ulcer disease, including eradicating H. pylori infection, reducing gastric acid secretion, and providing agents to protect the gastric mucosa from damage.
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