Peptic Ulcer Disease Treatment Options

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Questions and Answers

What are the two main causes of peptic ulcer disease?

  • Infection with gram-negative Helicobacter pylori and the use of corticosteroids (correct)
  • Infection with gram-negative Helicobacter pylori and the use of antihistamines
  • Infection with gram-positive Helicobacter pylori and the use of proton pump inhibitors (PPIs)
  • Infection with gram-positive Helicobacter pylori and the use of nonsteroidal anti-inflammatory drugs (NSAIDs)

How is infection with H. Pylori diagnosed?

  • Via electrocardiogram (ECG)
  • Via sputum culture
  • Via endoscopic biopsy of the gastric mucosa (correct)
  • Via MRI scanning

What is the recommended first-line treatment for patients with peptic ulcer disease who are infected with H. Pylori?

  • Quadruple therapy of bismuth subsalicylate, metronidazole, and tetracycline plus a PPI (correct)
  • Triple therapy of bismuth subsalicylate, metronidazole, and tetracycline plus a PPI
  • Dual therapy of bismuth subsalicylate and tetracycline
  • Monotherapy with a PPI

What is the role of misoprostol and sucralfate in the treatment of peptic ulcer disease?

<p>Protecting the gastric mucosa from damage (D)</p> Signup and view all the answers

When is triple therapy consisting of a PPI combined with amoxicillin plus clarithromycin a preferred treatment for peptic ulcer disease?

<p>When rates of clarithromycin resistance are low (C)</p> Signup and view all the answers

Eradicating the H. pylori infection. h.pylor kam bkainawa ba antibiotic

<p>treatment</p> Signup and view all the answers

Gastric mucosa aparezet laway trshakay bar bkawet gastric mucosa brinakaya kawata aw brina aparezet laway trshakay barbkawet w brinaka xraptr bet

<p>protecting</p> Signup and view all the answers

Patients with peptic ulcer disease (duodenal or gastric ulcers) who are infected with H. Pylori. require antimicrobial

<p>treatment</p> Signup and view all the answers

Currently, quadruple therapy of bismuth subsalicylate, metronidazole, and tetracycline plus a PPI is a recommended

<p>option</p> Signup and view all the answers

Triple therapy consisting of a PPI combined with amoxicillin (metronidazole may be used in penicillin-allergic patients) plus clarithromycin is a preferred treatment when rates of clarithromycin resistance are low and the patient has no prior exposure to macrolide

<p>antibiotics</p> Signup and view all the answers

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