COPY: CHAPTER 3 pharm
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How does absorption in pediatric patients differ from adults?

  • The gastric pH in pediatric patients is less acidic until 1-2 years of age (correct)
  • The first-pass elimination in pediatric patients is more efficient than in adults
  • The gastric emptying in pediatric patients is faster than in adults
  • The intramuscular absorption in pediatric patients is slower and regular
  • What factor affects drug distribution in pediatric patients?

  • Mature blood-brain barrier
  • Increased level of protein binding
  • Lower fat content (correct)
  • High fat content
  • Why might pediatric patients experience more side effects from drugs?

  • Decreased metabolism in pediatric patients
  • Immature blood-brain barrier allowing more drugs to enter the brain (correct)
  • Greater protein binding in pediatric patients
  • Lack of drug receptors in pediatric patients
  • What causes altered metabolism in pediatric patients?

    <p>Liver immaturity resulting in insufficient microsomal enzymes production</p> Signup and view all the answers

    How does kidney immaturity affect drug excretion in pediatric patients?

    <p>It reduces the excretion of drugs from the body</p> Signup and view all the answers

    Which factor affects pediatric drug doses according to the text?

    <p>Lack of bacteria-killing acid in the stomach</p> Signup and view all the answers

    What equipment preparation step is recommended when working with pediatric patients?

    <p>&quot;Prepare all equipment and supplies first&quot;</p> Signup and view all the answers

    What is one effect of pediatric patients having immature liver function?

    <p>&quot;First-pass elimination is reduced&quot;</p> Signup and view all the answers

    What is one effect of pediatric patients having a slowed gastric emptying?

    <p>Absorption is altered</p> Signup and view all the answers

    In pediatric patients, what is faster and irregular?

    <p>Intramuscular absorption</p> Signup and view all the answers

    What occurs with advancing age?

    <p>Decline in organ function</p> Signup and view all the answers

    Why might older children require higher doses of medication?

    <p>Increased metabolism</p> Signup and view all the answers

    Lifespan considerations have dramatic effects on the four phases of

    <p>Pharmacokinetics</p> Signup and view all the answers

    With pediatric patients, what do we assess before, during, and after drug administration?

    <p>Comfort</p> Signup and view all the answers

    Match

    <p>Drug therapy = Most likely to result in adverse effects and toxicity in older adults Absorptions = Altered due to gastric ph being less acidic and slowed GI functions in older adults. Distributions = Affected by lower total body water percentages, increased fat content, and decreased liver protein production in older adults. Excretion = Affected by decreased glomerular filtration rate and decreased number of nephrons causing drugs to be cleared less effectively.</p> Signup and view all the answers

    Older adult patients metabolism is altered due to aging liver and reduced blood flow to the liver.

    <p>True</p> Signup and view all the answers

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