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Questions and Answers
What does the suffix "-itis" in medical terminology indicate?
What does the suffix "-itis" in medical terminology indicate?
Which structure is NOT part of the upper respiratory tract?
Which structure is NOT part of the upper respiratory tract?
What role do goblet cells play in the respiratory tract?
What role do goblet cells play in the respiratory tract?
Which of these is an innate defense mechanism of the respiratory tract?
Which of these is an innate defense mechanism of the respiratory tract?
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Which component is NOT considered part of the mucosa-associated lymphoid tissue (MALT)?
Which component is NOT considered part of the mucosa-associated lymphoid tissue (MALT)?
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Which viral infections are classified as upper respiratory tract infections (URTIs)?
Which viral infections are classified as upper respiratory tract infections (URTIs)?
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What function does the mucociliary escalator serve in the respiratory system?
What function does the mucociliary escalator serve in the respiratory system?
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Which of the following is NOT a part of the lower respiratory tract?
Which of the following is NOT a part of the lower respiratory tract?
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What is the primary causative agent of the common cold?
What is the primary causative agent of the common cold?
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Which method is commonly used to diagnose the common cold?
Which method is commonly used to diagnose the common cold?
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What characteristic do respiratory tract microbiota and skin flora share?
What characteristic do respiratory tract microbiota and skin flora share?
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What is the main treatment strategy recommended for the common cold?
What is the main treatment strategy recommended for the common cold?
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How is respiratory synctial virus (RSV) classified?
How is respiratory synctial virus (RSV) classified?
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Which statement regarding normal microbiota is accurate?
Which statement regarding normal microbiota is accurate?
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What is a common symptom associated with the common cold?
What is a common symptom associated with the common cold?
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Transmission of the common cold primarily occurs through which method?
Transmission of the common cold primarily occurs through which method?
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Which statement accurately describes the respiratory tract microbiota?
Which statement accurately describes the respiratory tract microbiota?
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What is the primary method used to diagnose a common cold?
What is the primary method used to diagnose a common cold?
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Which of the following is a common transmission method for the common cold?
Which of the following is a common transmission method for the common cold?
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What is a significant risk associated with severe infections from the common cold?
What is a significant risk associated with severe infections from the common cold?
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Which virus is most commonly associated with the common cold?
Which virus is most commonly associated with the common cold?
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How does the normal microbiota of the respiratory tract compare to that of the skin?
How does the normal microbiota of the respiratory tract compare to that of the skin?
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Which of the following vaccines are available for conditions linked to respiratory infections?
Which of the following vaccines are available for conditions linked to respiratory infections?
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What symptom is least likely associated with the common cold?
What symptom is least likely associated with the common cold?
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Which structure is included in the upper respiratory tract?
Which structure is included in the upper respiratory tract?
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What role do alveolar macrophages play in the respiratory system?
What role do alveolar macrophages play in the respiratory system?
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Which of the following terms refers to inflammation of the bronchial tubes?
Which of the following terms refers to inflammation of the bronchial tubes?
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What is true regarding mucosa-associated lymphoid tissue (MALT)?
What is true regarding mucosa-associated lymphoid tissue (MALT)?
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Which virus is associated with the common cold?
Which virus is associated with the common cold?
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What is the primary function of ciliated epithelial cells in the respiratory tract?
What is the primary function of ciliated epithelial cells in the respiratory tract?
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What is a common symptom specifically associated with viral upper respiratory tract infections?
What is a common symptom specifically associated with viral upper respiratory tract infections?
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Which of the following is NOT a function of mucus in the respiratory tract?
Which of the following is NOT a function of mucus in the respiratory tract?
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Study Notes
Overview of Respiratory Tract
- Respiratory tract encompasses both the upper and lower respiratory tracts
- Upper respiratory tract (URT) includes the pharynx and epiglottis
- Lower respiratory tract (LRT) includes the trachea, bronchi, and lungs
Innate Defenses
- Respiratory tract includes innate defenses to combat pathogens
- Mucous membranes, including goblet cells, cilia, and the mucociliary escalator, trap and expel pathogens
- Mucosa-associated lymphoid tissue (MALT), including adenoids and tonsils, provides immune protection
- Alveolar macrophages engulf and destroy foreign invaders
- Normal microbiota competes with pathogenic microbes, limiting their colonization
Respiratory Tract Microbiota
- Similar to skin and mouth flora, may include opportunistic pathogens in low numbers
- Microbiota varies from person to person, influenced by factors like immune status and antibiotic use
Common Cold
- Caused by over 200 different viruses, including rhinoviruses and coronaviruses (40-60%)
- Rhinoviruses and coronaviruses are the most common culprits
- Transmission occurs through respiratory droplets and contact with fomites
- Symptoms include runny nose, sneezing, fatigue, coughing, stridor, dyspnea
- Severe infections can lead to pneumonia, inflammation of the alveoli
- Diagnosis is based on clinical symptoms or nasal/nasopharyngeal swabs
- Treatment is primarily supportive including rest, fluids, and over-the-counter medications
- RSV and ADV vaccines help protect against some forms of the common cold
RSV
- Respiratory syncytial virus (RSV) is an RNA, enveloped virus
- Can cause severe infections, especially in infants and the elderly
- Can lead to bronchiolitis, pneumonia, and respiratory distress
- Diagnosis is typically based on clinical presentation and nasal swab
- Treatment includes supportive care, oxygen therapy, and respiratory support in severe cases
Respiratory System Overview
- The respiratory tract is divided into the upper respiratory tract (URT) and the lower respiratory tract (LRT).
- The URT includes the pharynx and epiglottis.
- The LRT includes the trachea, bronchi, bronchioles, and alveoli.
Innate Defenses of the Respiratory Tract
- The respiratory tract has several innate defenses, including:
- Mucous membranes: Goblet cells secrete mucus, which traps pathogens.
- Ciliated epithelial cells: These cells beat rhythmically to move mucus and trapped pathogens up the respiratory tract (mucociliary escalator).
- Mucosa-associated lymphoid tissue (MALT): This tissue includes adenoids and tonsils, which are important for immune responses.
- Alveolar macrophages: These cells reside in the alveoli and phagocytize pathogens.
- Normal microbiota: The presence of normal microbiota helps to prevent the growth of harmful pathogens.
Respiratory Tract Microbiota
- The normal microbiota of the respiratory tract varies between individuals, depending on factors such as immune status, antibiotic use, and smoking.
- The upper respiratory tract and mouth contain similar microbiota to the skin.
- The lower respiratory tract is usually sterile, with transient microbes only.
Common Cold
- The common cold is caused by over 200 different viruses, including rhinoviruses, coronaviruses (40-60%), HPIV, RSV, and ADV.
- Transmission occurs through respiratory droplets and contact with fomites.
- Symptoms include runny nose, sneezing, fatigue, coughing, stridor, dyspnea.
- Severe infections can lead to pneumonia, which is inflammation of the alveoli.
- Diagnosis is based on clinical symptoms and can be confirmed with a nasal or nasopharyngeal swab using a NAAT (Nucleic Acid Amplification Test).
- Treatment is supportive care, aiming to manage symptoms.
- There are vaccines available for RSV and ADV.
RSV
- Respiratory Syncytial Virus (RSV) is an RNA, enveloped virus.
- It can cause more serious infections in children and infants.
- It causes bronchiolitis and pneumonia.
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Description
Explore the anatomy and function of the respiratory tract, including its innate defenses against pathogens. This quiz covers the upper and lower respiratory tracts, as well as the role of microbiota and common illnesses like the cold.