Salicylism Symptoms and Treatment Quiz with Flashcards

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Questions and Answers

What is the primary adverse effect associated with acetaminophen (Tylenol) overdose?

Gastrointestinal bleeding

Cardiac arrhythmias

Hepatotoxicity and liver failure (correct)

Acute kidney injury

Which of the following is a contraindication for the use of NSAIDs (non-steroidal anti-inflammatory drugs)?

Chronic kidney disease

Hypertension

Gastrointestinal bleeding

All of the above (correct)

Which of the following is a common sign or symptom of salicylism (salicylic acid toxicity)?

Diarrhea

Tinnitus (correct)

Constipation

Hypertension

Which of the following NSAID medications is a prescription-only drug?

Diclofenac (Voltaren) Signup and view all the answers

What is the primary therapeutic use of NSAIDs?

Both a and c Signup and view all the answers

What is the typical appearance of GI bleeding as described in the text?

Dark tarry stools Signup and view all the answers

Which of the following is NOT a common sign or symptom of salicylism (salicylic acid toxicity) mentioned in the text?

Fever Signup and view all the answers

What is the primary adverse effect associated with acetaminophen (Tylenol) overdose as described in the text?

Hepatotoxicity Signup and view all the answers

Which of the following is a contraindication for the use of NSAIDs (non-steroidal anti-inflammatory drugs) as mentioned in the text?

GI bleeds Signup and view all the answers

Which of the following NSAID medications is a prescription-only drug according to the text?

Celebrex (celecoxib) Signup and view all the answers

What is the primary adverse effect associated with the use of narcotics?

Sedation and respiratory depression Signup and view all the answers

Which of the following is a precaution for the use of narcotic analgesics?

Renal or hepatic dysfunction Signup and view all the answers

What is the primary mechanism of action of narcotic antagonists?

Binding to opiate receptor sites, thereby blocking opiates Signup and view all the answers

Which of the following is a common adverse reaction associated with the use of stimulants?

Dizziness and nervousness Signup and view all the answers

What is a contraindication for the use of amphetamine-based stimulants?

Epilepsy or convulsive states Signup and view all the answers

What is the primary therapeutic use of anticonvulsant medications?

Reducing seizure activity Signup and view all the answers

What is a precaution for the use of benzodiazepines?

Acute alcohol intoxication Signup and view all the answers

What is the primary adverse effect associated with the use of tricyclic antidepressants?

Lethargy and apathy Signup and view all the answers

What is the primary therapeutic use of bisphosphonate medications?

Treating or preventing osteoporosis Signup and view all the answers

What is a common adverse reaction associated with the use of xanthine oxidase inhibitors?

Upset stomach Signup and view all the answers

Study Notes

Pain Relief Medications

GI bleeding can resemble coffee ground vomit
Aspirin toxicity can cause salicylism, which may exhibit signs and symptoms such as:
- Dizziness
- Tinnitus
- Impaired hearing
- Nausea and vomiting
- Sweating
- Rapid deep breathing
- Confusion
- Coma

Acetaminophen (APAP)

Adverse reactions include:
- Hepatotoxicity
- Hepatic failure
Contraindications:
- Patients with acute alcohol toxicity
- Liver failure
- Alcoholics
Note: Signs and symptoms of Tylenol overdose may not show for 24 hours
- Nausea and vomiting
- Tinnitus
- Liver tenderness
- Hypotension
- Arrhythmias
- Jaundice
- Acute hepatic and renal failure

NSAIDs (Non-Steroidal Anti-Inflammatory Drugs)

OTC NSAIDs include:
- Aleve (naproxen)
- Advil/Motrin (ibuprofen)
RX NSAIDs include:
- Celebrex (celecoxib)
- Voltaren (diclofenac)
- Mobic (meloxicam)
Adverse reactions include:
- GI upset
- Abdominal pain
Contraindications:
- GI bleeds
- Patients on anticoagulants or blood thinners

Tylenol 3

Combination of acetaminophen and codeine
Adverse reactions include:
- Drowsiness
- State of sedation
- Respiratory depression
Precautions:
- Renal or hepatic impairment

Narcotics

Used for moderate to severe pain relief
Examples include:
- Duragesic (fentanyl)
- Demerol (meperidine)
- Dolophine (methadone)
- Morphine
- OxyContin (oxycodone)
- Norco/Vicodin (hydrocodone)
Adverse reactions include:
- Nausea and vomiting
- Sweating
- Increased blood pressure
- Tremors
- Tachycardia
- Sedation
- Respiratory depression
- Pinpoint pupils
Contraindications:
- Renal or hepatic dysfunction
Precautions:
- Elderly patients with confusion
- Liver problems
- History of addiction

Non-Narcotic Analgesic

Ultram (tramadol) is a common non-narcotic analgesic
Has anti-inflammatory and pain-relieving effects
Precautions:
- Can cause nephrotoxicity

Narcotic Antagonists

Used to reverse the effects of a narcotic overdose
Example: Narcan (naloxone)
Action: binds to opiate receptor sites, blocking opiates
Adverse reactions include:
- Nausea and vomiting
- Sweating
- Tachycardia
- Increased blood pressure
- Tremors
Precautions:
- CV disease
- Liver failure

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Description

This quiz provides an overview of pain management focusing on gastrointestinal bleeding, salicylism signs and symptoms like dizziness and tinnitus, as well as Tylenol (acetaminophen) adverse reactions such as hepatic failure. Test your knowledge on contraindications and manifestations of these conditions.

Overview of Pain: GI Bleeding, Salicylism, and Tylenol Toxicity