20 Questions
What is the primary adverse effect associated with acetaminophen (Tylenol) overdose?
Hepatotoxicity and liver failure
Which of the following is a contraindication for the use of NSAIDs (non-steroidal anti-inflammatory drugs)?
All of the above
Which of the following is a common sign or symptom of salicylism (salicylic acid toxicity)?
Tinnitus
Which of the following NSAID medications is a prescription-only drug?
Diclofenac (Voltaren)
What is the primary therapeutic use of NSAIDs?
Both a and c
What is the typical appearance of GI bleeding as described in the text?
Dark tarry stools
Which of the following is NOT a common sign or symptom of salicylism (salicylic acid toxicity) mentioned in the text?
Fever
What is the primary adverse effect associated with acetaminophen (Tylenol) overdose as described in the text?
Hepatotoxicity
Which of the following is a contraindication for the use of NSAIDs (non-steroidal anti-inflammatory drugs) as mentioned in the text?
GI bleeds
Which of the following NSAID medications is a prescription-only drug according to the text?
Celebrex (celecoxib)
What is the primary adverse effect associated with the use of narcotics?
Sedation and respiratory depression
Which of the following is a precaution for the use of narcotic analgesics?
Renal or hepatic dysfunction
What is the primary mechanism of action of narcotic antagonists?
Binding to opiate receptor sites, thereby blocking opiates
Which of the following is a common adverse reaction associated with the use of stimulants?
Dizziness and nervousness
What is a contraindication for the use of amphetamine-based stimulants?
Epilepsy or convulsive states
What is the primary therapeutic use of anticonvulsant medications?
Reducing seizure activity
What is a precaution for the use of benzodiazepines?
Acute alcohol intoxication
What is the primary adverse effect associated with the use of tricyclic antidepressants?
Lethargy and apathy
What is the primary therapeutic use of bisphosphonate medications?
Treating or preventing osteoporosis
What is a common adverse reaction associated with the use of xanthine oxidase inhibitors?
Upset stomach
Study Notes
Pain Relief Medications
- GI bleeding can resemble coffee ground vomit
- Aspirin toxicity can cause salicylism, which may exhibit signs and symptoms such as:
- Dizziness
- Tinnitus
- Impaired hearing
- Nausea and vomiting
- Sweating
- Rapid deep breathing
- Confusion
- Coma
Acetaminophen (APAP)
- Adverse reactions include:
- Hepatotoxicity
- Hepatic failure
- Contraindications:
- Patients with acute alcohol toxicity
- Liver failure
- Alcoholics
- Note: Signs and symptoms of Tylenol overdose may not show for 24 hours
- Nausea and vomiting
- Tinnitus
- Liver tenderness
- Hypotension
- Arrhythmias
- Jaundice
- Acute hepatic and renal failure
NSAIDs (Non-Steroidal Anti-Inflammatory Drugs)
- OTC NSAIDs include:
- Aleve (naproxen)
- Advil/Motrin (ibuprofen)
- RX NSAIDs include:
- Celebrex (celecoxib)
- Voltaren (diclofenac)
- Mobic (meloxicam)
- Adverse reactions include:
- GI upset
- Abdominal pain
- Contraindications:
- GI bleeds
- Patients on anticoagulants or blood thinners
Tylenol 3
- Combination of acetaminophen and codeine
- Adverse reactions include:
- Drowsiness
- State of sedation
- Respiratory depression
- Precautions:
- Renal or hepatic impairment
Narcotics
- Used for moderate to severe pain relief
- Examples include:
- Duragesic (fentanyl)
- Demerol (meperidine)
- Dolophine (methadone)
- Morphine
- OxyContin (oxycodone)
- Norco/Vicodin (hydrocodone)
- Adverse reactions include:
- Nausea and vomiting
- Sweating
- Increased blood pressure
- Tremors
- Tachycardia
- Sedation
- Respiratory depression
- Pinpoint pupils
- Contraindications:
- Renal or hepatic dysfunction
- Precautions:
- Elderly patients with confusion
- Liver problems
- History of addiction
Non-Narcotic Analgesic
- Ultram (tramadol) is a common non-narcotic analgesic
- Has anti-inflammatory and pain-relieving effects
- Precautions:
- Can cause nephrotoxicity
Narcotic Antagonists
- Used to reverse the effects of a narcotic overdose
- Example: Narcan (naloxone)
- Action: binds to opiate receptor sites, blocking opiates
- Adverse reactions include:
- Nausea and vomiting
- Sweating
- Tachycardia
- Increased blood pressure
- Tremors
- Precautions:
- CV disease
- Liver failure
This quiz provides an overview of pain management focusing on gastrointestinal bleeding, salicylism signs and symptoms like dizziness and tinnitus, as well as Tylenol (acetaminophen) adverse reactions such as hepatic failure. Test your knowledge on contraindications and manifestations of these conditions.
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