Oral Pathology: Wound Healing and Bone Repair

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What is the main characteristic of hypertrophic scars?

It is a type of wound that heals quickly

It is a type of chronic wound

It forms a contracture

It is a macroscopic disturbance of normal skin architecture (correct)

Why do oral wounds tend to heal faster than skin wounds?

Due to the presence of necrotic tissue

Due to the moist, antibacterial, and clotting properties of saliva (correct)

Due to the presence of bacteria

Due to the presence of foreign material

What is the main factor that affects wound healing in patients with diabetes?

Systemic disease (correct)

Age

Nutrition

Local type of wound

What is the purpose of recombinant growth factors in wound healing?

To enhance the growth of new tissue Signup and view all the answers

What is the main characteristic of chronic wounds?

They are stuck in the inflammatory phase Signup and view all the answers

What is the purpose of negative pressure/vacuum therapy in wound healing?

To remove bacteria and debris from the wound Signup and view all the answers

What is the main difference between oral and skin wound healing?

Oral wounds have a more rapid and quickly resolved immune response Signup and view all the answers

What is the primary goal of wound healing?

To restore tissue integrity Signup and view all the answers

What phase of wound healing involves vessel rupture and bleeding?

Haemostasis Signup and view all the answers

What type of wound closure is characterized by wound edges being closed surgically?

Primary intention Signup and view all the answers

What factor can delay wound healing?

All of the above Signup and view all the answers

What is the result of repair in wound healing?

Lost tissue is replaced by fibrous scar Signup and view all the answers

What is the difference between labile and permanent cells in wound healing?

Labile cells divide frequently, while permanent cells do not divide Signup and view all the answers

Why do oral wounds heal faster and without scarring?

Due to the specific type of tissue Signup and view all the answers

What is the main function of macrophages in the granulation tissue?

Phagocytosis and secretion Signup and view all the answers

What type of collagen is initially formed during the wound healing process?

Type III collagen Signup and view all the answers

What is the percentage of wound strength achieved at 7-10 days?

10% Signup and view all the answers

What is the term for the process of reducing cell and capillary density during the remodelling phase?

Proteolysis Signup and view all the answers

What type of wound closure involves bringing the wound edges together using mechanical means?

Primary intention Signup and view all the answers

What is the purpose of endothelial cells in the granulation tissue?

Formation of new blood vessels Signup and view all the answers

At what time period does the wound reach 70-80% strength?

2-3 months Signup and view all the answers

What is the primary function of platelets in the wound healing process?

To form a thrombus and trap themselves within the clot Signup and view all the answers

Which of the following is a key cell in the early phase of wound healing?

Neutrophil Signup and view all the answers

What is the primary function of neutrophils in wound healing?

To remove bacteria and foreign material Signup and view all the answers

What is the role of cytokines and growth factors in wound healing?

To act as chemo-attractants Signup and view all the answers

Which of the following is a key cell in the later phase of wound healing?

Fibroblast Signup and view all the answers

What is the role of macrophages in wound healing?

To phagocytose remaining debris and secrete cytokines and growth factors Signup and view all the answers

What is the result of vasodilation in wound healing?

Increased blood flow Signup and view all the answers

Which of the following is NOT a key cell in wound healing?

Erythrocyte Signup and view all the answers

What is the role of prostaglandins, leukotrienes, and histamine in wound healing?

To cause vasodilation Signup and view all the answers

What is the result of granulation tissue formation?

Wound closure Signup and view all the answers

What is the primary function of fibroblasts in granulation tissue?

Collagen production Signup and view all the answers

What is the characteristics of wound healing by primary intention?

Wound edges are brought together surgically Signup and view all the answers

During which phase of wound healing is there a reduction in cell and capillary density?

Remodelling Signup and view all the answers

What is the role of vitamin C in wound healing?

Enhancing collagen production Signup and view all the answers

What type of collagen is replaced by type I collagen during the remodelling phase?

Type III collagen Signup and view all the answers

What is the percentage of wound strength achieved at 2-3 months after wound formation?

70-80% Signup and view all the answers

What is the function of proteases during the remodelling phase?

Breaking down collagen Signup and view all the answers

What is the primary difference between regeneration and repair in wound healing?

Regeneration replaces lost tissue with the same type, whereas repair replaces it with fibrous scar Signup and view all the answers

What determines the type of wound healing process that occurs?

The cell type, tissue architecture, and amount of tissue lost Signup and view all the answers

What is the primary goal of the haemostasis phase of wound healing?

To stop bleeding and restore vascular integrity Signup and view all the answers

Which of the following can delay wound healing?

Smoking or having diabetes Signup and view all the answers

What is the primary characteristic of chronic wounds?

They are unable to heal and persist over time Signup and view all the answers

What is the primary function of the proliferation phase of wound healing?

To stimulate the growth of new tissue Signup and view all the answers

What is the primary purpose of the remodelling phase of wound healing?

To strengthen and reorganize the newly formed tissue Signup and view all the answers

What is the primary goal of assisted wound care?

To enhance the healing process and prevent complications Signup and view all the answers

Which of the following is a systemic factor that can affect wound healing?

Nutritional deficiency (Vitamin C, Zinc) Signup and view all the answers

What is a characteristic of chronic wounds?

Accumulation of pro-inflammatory signals and macrophages Signup and view all the answers

What type of wound closure involves bringing the wound edges together using mechanical means?

Primary closure Signup and view all the answers

What is the purpose of maggot therapy in wound healing?

To remove dead tissue and bacteria Signup and view all the answers

During which phase of wound healing do fibroblasts migrate and contract?

Proliferative phase Signup and view all the answers

What is the purpose of hyperbaric oxygen therapy in wound healing?

To enhance collagen synthesis and angiogenesis Signup and view all the answers

What is the primary function of platelets in wound healing?

To trap within the clot and form thrombus Signup and view all the answers

What is the role of cytokines and growth factors in wound healing?

To act as chemo-attractants Signup and view all the answers

What is the result of vasodilation in wound healing?

Increased blood flow to the wound site Signup and view all the answers

What is the primary function of neutrophils in wound healing?

To remove bacteria and foreign material Signup and view all the answers

What is the role of macrophages in wound healing?

To proliferate and secrete growth factors Signup and view all the answers

What type of cells are fibroblasts?

Labile cells Signup and view all the answers

What is the result of granulation tissue formation?

Proliferation of key cells Signup and view all the answers

What is the function of thrombus formation?

To act as a glue to hold the wound together Signup and view all the answers

What is the role of prostaglandins, leukotrienes, and histamine in wound healing?

To cause vasodilation Signup and view all the answers

What type of cells are recruited from the circulation to the wound site?

Blood monocytes Signup and view all the answers

What is the primary role of endothelial cells in granulation tissue?

Formation of new blood vessels Signup and view all the answers

Which of the following phases of wound healing is characterized by a reduction in cell and capillary density?

Remodelling phase Signup and view all the answers

What percentage of wound strength is achieved at 2-3 months after wound formation?

70-80% Signup and view all the answers

What is the purpose of proteases during the remodelling phase of wound healing?

Breakdown of collagen Signup and view all the answers

What type of wound closure involves bringing the wound edges together naturally by means of granulation and contraction?

Secondary intention Signup and view all the answers

What is the role of vitamin C in wound healing?

Collagen synthesis Signup and view all the answers

During which phase of wound healing is type III collagen replaced by type I collagen?

Remodelling phase Signup and view all the answers

What is the primary purpose of hyperbaric oxygen therapy in wound healing?

To increase oxygen delivery to the wound site Signup and view all the answers

Which of the following is a local factor that can affect wound healing?

Foreign body presence Signup and view all the answers

What is the main difference between wound healing by primary and secondary intention?

Primary intention involves closing the wound surgically, secondary intention involves letting the wound close on its own Signup and view all the answers

What is the primary characteristic of hypertrophic scars?

Abnormal collagen remodelling Signup and view all the answers

What is the primary purpose of matrix materials in wound healing?

To provide a scaffold for tissue growth Signup and view all the answers

What determines whether wound healing proceeds by regeneration or repair?

All of the above Signup and view all the answers

What is the primary difference between primary and secondary wound closure?

Primary closure involves bringing the wound edges together, while secondary closure involves granulation Signup and view all the answers

What is the primary goal of the haemostasis phase of wound healing?

To stop bleeding and activate coagulation cascade Signup and view all the answers

During which phase of wound healing do macrophages play a crucial role?

Inflammation Signup and view all the answers

What can lead to chronic wounds?

All of the above Signup and view all the answers

What is the primary goal of the proliferation phase of wound healing?

To produce granulation tissue Signup and view all the answers

What type of wound closure is characterized by bringing the wound edges together using mechanical means?

Primary intention Signup and view all the answers

Which phase of wound healing involves the reduction of cell and capillary density?

Remodelling Signup and view all the answers

What is a common consequence of impaired wound healing?

All of the above Signup and view all the answers

Which of the following is NOT released by platelets during the haemostasis phase of wound healing?

Insulin Signup and view all the answers

Which type of wound closure is characterized by the use of sutures or staples?

Surgical closure Signup and view all the answers

What is the primary function of prostaglandins, leukotrienes, and histamine in wound healing?

To promote vasodilation Signup and view all the answers

Which of the following is a characteristic of chronic wounds?

Delayed healing rate Signup and view all the answers

What is the primary function of macrophages in the granulation tissue?

To phagocytose bacteria Signup and view all the answers

Which phase of wound healing is characterized by the proliferation of fibroblasts and the synthesis of collagen?

Proliferation Signup and view all the answers

What is the primary function of cytokines and growth factors in wound healing?

To stimulate cell proliferation and differentiation Signup and view all the answers

Oral Pathology: Wound Healing and Bone Repair

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Questions and Answers

What is the main characteristic of hypertrophic scars?

Why do oral wounds tend to heal faster than skin wounds?

What is the main factor that affects wound healing in patients with diabetes?

What is the purpose of recombinant growth factors in wound healing?

What is the main characteristic of chronic wounds?

What is the purpose of negative pressure/vacuum therapy in wound healing?

What is the main difference between oral and skin wound healing?

What is the primary goal of wound healing?

What phase of wound healing involves vessel rupture and bleeding?

What type of wound closure is characterized by wound edges being closed surgically?

What factor can delay wound healing?

What is the result of repair in wound healing?

What is the difference between labile and permanent cells in wound healing?

Why do oral wounds heal faster and without scarring?

What is the main function of macrophages in the granulation tissue?

What type of collagen is initially formed during the wound healing process?

What is the percentage of wound strength achieved at 7-10 days?

What is the term for the process of reducing cell and capillary density during the remodelling phase?

What type of wound closure involves bringing the wound edges together using mechanical means?

What is the purpose of endothelial cells in the granulation tissue?

At what time period does the wound reach 70-80% strength?

What is the primary function of platelets in the wound healing process?

Which of the following is a key cell in the early phase of wound healing?

What is the primary function of neutrophils in wound healing?

What is the role of cytokines and growth factors in wound healing?

Which of the following is a key cell in the later phase of wound healing?

What is the role of macrophages in wound healing?

What is the result of vasodilation in wound healing?

Which of the following is NOT a key cell in wound healing?

What is the role of prostaglandins, leukotrienes, and histamine in wound healing?

What is the result of granulation tissue formation?

What is the primary function of fibroblasts in granulation tissue?

What is the characteristics of wound healing by primary intention?

During which phase of wound healing is there a reduction in cell and capillary density?

What is the role of vitamin C in wound healing?

What type of collagen is replaced by type I collagen during the remodelling phase?

What is the percentage of wound strength achieved at 2-3 months after wound formation?

What is the function of proteases during the remodelling phase?

What is the primary difference between regeneration and repair in wound healing?

What determines the type of wound healing process that occurs?

What is the primary goal of the haemostasis phase of wound healing?

Which of the following can delay wound healing?

What is the primary characteristic of chronic wounds?

What is the primary function of the proliferation phase of wound healing?

What is the primary purpose of the remodelling phase of wound healing?

What is the primary goal of assisted wound care?

Which of the following is a systemic factor that can affect wound healing?

What is a characteristic of chronic wounds?

What type of wound closure involves bringing the wound edges together using mechanical means?

What is the purpose of maggot therapy in wound healing?

During which phase of wound healing do fibroblasts migrate and contract?

What is the purpose of hyperbaric oxygen therapy in wound healing?

What is the primary function of platelets in wound healing?

What is the role of cytokines and growth factors in wound healing?

What is the result of vasodilation in wound healing?

What is the primary function of neutrophils in wound healing?

What is the role of macrophages in wound healing?

What type of cells are fibroblasts?

What is the result of granulation tissue formation?

What is the function of thrombus formation?

What is the role of prostaglandins, leukotrienes, and histamine in wound healing?

What type of cells are recruited from the circulation to the wound site?

What is the primary role of endothelial cells in granulation tissue?

Which of the following phases of wound healing is characterized by a reduction in cell and capillary density?

What percentage of wound strength is achieved at 2-3 months after wound formation?

What is the purpose of proteases during the remodelling phase of wound healing?

What type of wound closure involves bringing the wound edges together naturally by means of granulation and contraction?

What is the role of vitamin C in wound healing?

During which phase of wound healing is type III collagen replaced by type I collagen?

What is the primary purpose of hyperbaric oxygen therapy in wound healing?

Which of the following is a local factor that can affect wound healing?

What is the main difference between wound healing by primary and secondary intention?

What is the primary characteristic of hypertrophic scars?

What is the primary purpose of matrix materials in wound healing?

What determines whether wound healing proceeds by regeneration or repair?

What is the primary difference between primary and secondary wound closure?

What is the primary goal of the haemostasis phase of wound healing?