Oncogenes and Tumor Suppressor Genes Quiz
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Questions and Answers

What is the function of PCNA (proliferating cell nuclear antigen) in DNA replication?

  • It is involved in signal transduction
  • It acts as a tumor suppressor gene
  • It acts as a scaffold to recruit proteins for DNA replication (correct)
  • It encodes for growth factors

    • Which gene is suitable to identify patients with head and neck squamous cell carcinoma at risk for local and loco regional recurrence?

  • FHIT
  • TP53 (correct)
  • pl6INK4A
  • ras

    • What is the purpose of the American Joint Committee on Cancer tumor-node-metastases staging system for oral cancer?

  • To reflect prognosis prior to treatment (correct)
  • To regulate cell growth and differentiation
  • To negatively regulate cell growth
  • To encode for growth factors

    • What is the maximum to minimum order of aggressive behavior in high-risk types of basal cell carcinoma (BCC)?

    <p>Morphea-form &gt; Infiltrative &gt; Superficial &gt; Micronodular</p> Signup and view all the answers

    What is the most common cause of squamous cell carcinoma?

    <p>UV solar radiation</p> Signup and view all the answers

    What is a clinical feature of squamous cell carcinoma?

    <p>Lip paresthesia</p> Signup and view all the answers

    Where do most keratoacanthomas occur?

    <p>On sun-exposed areas</p> Signup and view all the answers

    What is the most characteristic feature of keratoacanthoma lesions?

    <p>Elevated normal adjacent epithelium</p> Signup and view all the answers

    What is the gender distribution of keratoacanthoma occurrences?

    <p>Twice as frequent in men</p> Signup and view all the answers

    Which factor is implicated as an etiologic factor for keratoacanthoma?

    <p>Immunocompromised status</p> Signup and view all the answers

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