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Oncogenes and Tumor Suppressor Genes Quiz

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Oncogenes and Tumor Suppressor Genes Quiz

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Questions and Answers

What is the function of PCNA (proliferating cell nuclear antigen) in DNA replication?

It is involved in signal transduction

It acts as a tumor suppressor gene

It acts as a scaffold to recruit proteins for DNA replication (correct)

It encodes for growth factors

Which gene is suitable to identify patients with head and neck squamous cell carcinoma at risk for local and loco regional recurrence?

FHIT

TP53 (correct)

pl6INK4A

ras

What is the purpose of the American Joint Committee on Cancer tumor-node-metastases staging system for oral cancer?

To reflect prognosis prior to treatment (correct)

To regulate cell growth and differentiation

To negatively regulate cell growth

To encode for growth factors

What is the maximum to minimum order of aggressive behavior in high-risk types of basal cell carcinoma (BCC)?

Morphea-form > Infiltrative > Superficial > Micronodular Signup and view all the answers

What is the most common cause of squamous cell carcinoma?

UV solar radiation Signup and view all the answers

What is a clinical feature of squamous cell carcinoma?

Lip paresthesia Signup and view all the answers

Where do most keratoacanthomas occur?

On sun-exposed areas Signup and view all the answers

What is the most characteristic feature of keratoacanthoma lesions?

Elevated normal adjacent epithelium Signup and view all the answers

What is the gender distribution of keratoacanthoma occurrences?

Twice as frequent in men Signup and view all the answers

Which factor is implicated as an etiologic factor for keratoacanthoma?

Immunocompromised status Signup and view all the answers