Oncogenes and Tumor Suppressor Genes Quiz

Which type of gene had the highest frequency of mutations in all tumor samples?

What percentage of tumor suppressor genes were mutated in breast cancer?

In which type of cancer did CDK6 show the highest mutation frequency?

What was the mutation frequency of phosphatases in thyroid cancer?

Which cancer type had the lowest mutation frequency in transcription factors, and what was that frequency?

How does the mutation frequency of KRAS compare between lung cancer and colorectal cancer?

Which gene had the highest mutation rate across the cancers listed in relation to tumor suppressor genes?

What percentage of kinases were mutated in stomach cancer?

Which tumor type had the highest frequency of mutated oncogenes according to Table 2?

For which gene was the mutation frequency zero in thyroid cancer?

Table 1: Frequency of Driver Gene Mutations

Mutations of driver genes in various classes of tumor samples are presented
Oncogenes show a frequency of 89.4%
Tumor suppressor genes show a frequency of 90.5%
Kinases show a frequency of 61.8%
Phosphatases show a frequency of 19.3%
Transcription factors show a frequency of 72.2%

Table 2: Frequency of Altered Genes in Common Cancers

This table shows the frequency of altered genes (transcription factors, kinases, phosphatases, oncogenes, and tumor suppressor genes) in different cancers.
Lung cancer oncogenes are at 98.3%
Colorectal cancer oncogenes are at 98.2%
Breast cancer oncogenes are at 92.9%
Prostate cancer oncogenes are at 86.3%
Stomach cancer oncogenes are at 96.7%
Liver cancer oncogenes are at 92.6%
Lung cancer tumor suppressor genes show a frequency of 98.85%
Colorectal cancer tumor suppressor genes are at 99.3%
Breast cancers are at 95.1%
Prostate is at 93.7%
Stomach cancer is at 99.5%
Liver cancer tumor suppressor genes are at 97.3%
Further analyses of frequencies of altered genes in specific cancers (lung, breast, colorectal, prostate, stomach, liver, cervical, and bladder) are shown in the table

Table 3: Frequency of Mutations in Specific Genes Across Cancer Types

This table presents the frequency of mutations in particular genes (CDK4, CDK6, TP53, KRAS, RB1) across various cancer types (lung, breast, colorectal, prostate, stomach, liver, thyroid, cervix, and bladder).
The frequency of mutations in these genes varies significantly across cancer types, highlighting gene-specific mutational patterns for different cancers.

This quiz explores the frequency of driver gene mutations in various tumor samples and their prevalence in common cancers. Test your knowledge on oncogenes, tumor suppressor genes, and other genetic alterations seen in lung, colorectal, breast, prostate, stomach, and liver cancers.