5 Questions
Which statement best describes oncogenes?
Oncogenes are mutated forms of proto-oncogenes that cause overactive stimulatory proteins leading to excessive cell proliferation
What is the role of tumor suppressor genes?
Tumor suppressor genes slow down cell division or promote programmed cell death
What is the function of TP53, an important tumor suppressor gene?
TP53 helps keep cell division under control
What factors can lead to cancer progression?
All of the above
Which statement is true about the initiation and progression of cancer?
It depends on both external factors and internal factors
Study Notes
- Oncogenes are mutated forms of proto-oncogenes, which code for proteins that stimulate excessive cell division.
- Oncogenes result in the overactivity of stimulatory proteins, leading to uncontrollable cell proliferation.
- An example of an oncogene is not provided in the text.
- Tumor suppressor genes, on the other hand, are normal genes that slow down cell division or trigger apoptosis, preventing uncontrolled cell growth.
- TP53 is a specific example of a tumor suppressor gene, coding for the p53 protein that helps regulate cell division.
- Factors that contribute to cancer progression include both external environmental factors, such as tobacco, alcohol, radiation, and infectious microbes, and internal factors, including aging, inherited mutations, and immune conditions.
- The text suggests that these factors can act independently or in combination, leading to abnormal cell behavior and excessive proliferation.
Test your knowledge of oncogenes and tumor suppressor genes, which play crucial roles in regulating cell division and proliferation. Understand the differences between these two types of genes and their impact on cellular processes.
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