Podcast
Questions and Answers
Which of the following nonbenzodiazepine hypnotics is a melatonin receptor agonist?
Which of the following nonbenzodiazepine hypnotics is a melatonin receptor agonist?
- Zolpidem (Ambien)
- Ramelteon (Rozerem) (correct)
- Zaleplon (Sonata)
- Eszopiclone (Lunesta)
What is the mechanism of action of the orexin receptor antagonist suvorexant (Belsomra)?
What is the mechanism of action of the orexin receptor antagonist suvorexant (Belsomra)?
- It blocks the binding of orexin to the GABA receptor
- It blocks the binding of orexin to the benzodiazepine receptor
- It blocks the binding of orexin to the melatonin receptor
- It blocks the binding of orexin to the orexin A and orexin B receptors (correct)
Which of the following statements about the pharmacokinetics of nonbenzodiazepine hypnotics is correct?
Which of the following statements about the pharmacokinetics of nonbenzodiazepine hypnotics is correct?
- They have long half-lives, ranging from 10 to 20 hours
- They have short half-lives, ranging from 1 to 5.8 hours (correct)
- They are not protein bound
- They are slowly absorbed through oral administration
Which of the following is NOT a nonbenzodiazepine hypnotic mentioned in the text?
Which of the following is NOT a nonbenzodiazepine hypnotic mentioned in the text?
What is the percentage of protein binding for zolpidem?
What is the percentage of protein binding for zolpidem?
What is the peak onset time for ramelteon after oral administration?
What is the peak onset time for ramelteon after oral administration?
What is the recommended initial dose of suvorexant?
What is the recommended initial dose of suvorexant?
Which drug should be preferred for patients with a history of drug or alcohol abuse?
Which drug should be preferred for patients with a history of drug or alcohol abuse?
What is the maximum daily dose of zolpidem sublingual tablets for women and older patients?
What is the maximum daily dose of zolpidem sublingual tablets for women and older patients?
When should these nonbenzodiazepine drugs be taken according to patient education?
When should these nonbenzodiazepine drugs be taken according to patient education?
Which drug class includes medications used primarily for sedation during episodes of insomnia?
Which drug class includes medications used primarily for sedation during episodes of insomnia?
What consequence can occur if patients combine these drugs with over-the-counter sleeping aids or alcohol?
What consequence can occur if patients combine these drugs with over-the-counter sleeping aids or alcohol?
