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Questions and Answers
What is the primary mechanism of action of nonbenzodiazepine hypnotics?
What is the primary mechanism of action of nonbenzodiazepine hypnotics?
- They act at the orexin receptors in the hypothalamus
- They do not act at the GABA receptor, but at a different receptor site (correct)
- They act at the benzodiazepine site of the GABA receptor
- They act as melatonin receptor agonists
Which of the following is not a nonbenzodiazepine hypnotic?
Which of the following is not a nonbenzodiazepine hypnotic?
- Zolpidem
- Zaleplon
- Zopiclone (correct)
- Eszopiclone
What is the primary mechanism of action of ramelteon?
What is the primary mechanism of action of ramelteon?
- It acts as a melatonin receptor agonist (correct)
- It acts as an orexin receptor antagonist
- It acts at the GABA receptor
- It acts at the benzodiazepine site of the GABA receptor
What is the primary mechanism of action of suvorexant?
What is the primary mechanism of action of suvorexant?
Which of the following nonbenzodiazepine hypnotics has the shortest half-life?
Which of the following nonbenzodiazepine hypnotics has the shortest half-life?
Which nonbenzodiazepine hypnotic has the highest protein binding?
Which nonbenzodiazepine hypnotic has the highest protein binding?
What is the recommended initial dose of suvorexant for a patient not on a moderate CYP3A4 inhibitor?
What is the recommended initial dose of suvorexant for a patient not on a moderate CYP3A4 inhibitor?
What is the recommended dose of suvorexant for a patient who is on a moderate CYP3A4 inhibitor?
What is the recommended dose of suvorexant for a patient who is on a moderate CYP3A4 inhibitor?
Which of the following is NOT a recommended dosing practice for the nonbenzodiazepine gaba-ergic drugs?
Which of the following is NOT a recommended dosing practice for the nonbenzodiazepine gaba-ergic drugs?
Which of the following statements about ramelteon is correct?
Which of the following statements about ramelteon is correct?
What is the maximum recommended dose of zolpidem for older adults or women?
What is the maximum recommended dose of zolpidem for older adults or women?
Which of the following is an important patient education recommendation for the nonbenzodiazepine gaba-ergic drugs?
Which of the following is an important patient education recommendation for the nonbenzodiazepine gaba-ergic drugs?
What is the peak onset time of suvorexant when taken on an empty stomach?
What is the peak onset time of suvorexant when taken on an empty stomach?
Which enzyme is primarily responsible for the metabolism of suvorexant?
Which enzyme is primarily responsible for the metabolism of suvorexant?
Which of the following is NOT a precaution or contraindication for nonbenzodiazepine hypnotics?
Which of the following is NOT a precaution or contraindication for nonbenzodiazepine hypnotics?
Which of the following is a potential adverse effect of suvorexant?
Which of the following is a potential adverse effect of suvorexant?
Which of the following drugs should NOT be used concomitantly with suvorexant?
Which of the following drugs should NOT be used concomitantly with suvorexant?
Which nonbenzodiazepine hypnotic is NOT a controlled substance?
Which nonbenzodiazepine hypnotic is NOT a controlled substance?
Which pathway is primarily responsible for the excretion of suvorexant?
Which pathway is primarily responsible for the excretion of suvorexant?
Which of the following is a common side effect of nonbenzodiazepine hypnotics?
Which of the following is a common side effect of nonbenzodiazepine hypnotics?
Which statement about the nonbenzodiazepine hypnotics is TRUE?
Which statement about the nonbenzodiazepine hypnotics is TRUE?
Which of the following is a potential adverse effect of suvorexant reported in clinical trials?
Which of the following is a potential adverse effect of suvorexant reported in clinical trials?
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