19 Questions
What was the reason for discarding the first two volumes in the initial analysis (Aron & Poldrack, 2006)?
To adjust for T1 equilibrium effects
Why were the images thresholded at p < 0.01 in the analyses (Aron & Poldrack, 2006)?
To reduce false positives
What method was used to denoise the images in the analysis (Aron & Poldrack, 2006)?
MELODIC independent components analysis
How were the data spatially smoothed in this study (Aron & Poldrack, 2006)?
Using a 5 mm full-width-half-maximum Gaussian kernel
What was the purpose of using small volume correction (SVC) in this study (Aron & Poldrack, 2006)?
To reduce type I errors
What may be the consequence if such segregation is maintained at subsequent stations in the pallidum and thalamus (Alexander & Crutcher, 1990)?
Enhanced functional specificity of information processing within the globus pallidus
What is the role of putamen in the motor circuit (Alexander & Crutcher, 1990)?
Projects to specific portions of GPe, GPi, and SNr
Which thalamic nucleus receives projections from lateral VAmc and VLo in the motor circuit (Alexander & Crutcher, 1990)?
VApc
What is the role of lateral VApc in the motor circuit (Alexander & Crutcher, 1990)?
Projects to the premotor cortex
What has been suggested as a consequence of the spatial convergence of the striatopallidal projection (Alexander & Crutcher, 1990)?
Degraded functional specificity within the globus pallidus
What is the role of the cortical dopamine system according to Goldman-Rakic PS (Tichelaar et al., 2023)?
Facilitation of memory and cognition
In the context of reinforcement learning, what did O’Doherty JP, Hampton A, Kim H focus on (Tichelaar et al., 2023)?
Decision making and reward learning
Which area plays a significant role in prediction error in reinforcement learning based on Garrison J, Erdeniz B, Done J (Tichelaar et al., 2023)?
Prefrontal cortex
According to Anne GEC, Matthew AA, James AW, James MG, Michael JF, what selective deficits in schizophrenia were identified (Tichelaar et al., 2023)?
Impaired working memory and reinforcement learning
What was the estimated incidence of severe micrographia in the population of Parkinsonian patients (McLennan et al., 1971)?
15%
Which source of handwriting samples was found to be the most standardized and easily obtainable for analysis in Parkinsonian patients (McLennan et al., 1971)?
Serial signatures from cancelled checks
What percentage of the contacted patients were able to respond to the detailed questionnaire about their handwriting and symptoms progression (McLennan et al., 1971)?
70%
In the study comparing levodopa to procyclidine hydrochloride and a placebo, how many patients provided serial signatures for analyzing the effect of therapy on micrographia?
30
Why was there considerable difficulty in getting Parkinsonian patients to complete a long questionnaire requiring handwriting exercises and concentration (McLennan et al., 1971)?
Cognitive challenges due to the disease
Explore the activation contrasts observed in fMRI studies related to voluntary movement and inhibiting potential responses. Learn about putative left STN activation, putamen activation, and contralateral Go network activations discussed in the text.
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