Neurodevelopmental Disorders Overview
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Questions and Answers

What is a key characteristic of ADHD that differentiates it from other disorders?

  • Symptoms include both inattentive and hyperactive behaviors. (correct)
  • Focus on social-emotional reciprocity.
  • Symptoms must be present in only one setting.
  • Onset of symptoms must occur after age 12.

Which factor is NOT a component of the biological etiology for ADHD?

  • Neurotransmitter dysregulation
  • Frequent relocations (correct)
  • Prenatal complications
  • Cerebral cortex size

Which of the following is a hallmark of ASD according to the DSM-5-TR?

  • Difficulty waiting for turns
  • Deficits in social-emotional reciprocity (correct)
  • Excessive talking
  • Inattention to details

Which is a typical treatment option for ADHD?

<p>Behavioral therapy reinforcing goal-directed behaviors (A)</p> Signup and view all the answers

At what age must symptoms of ADHD manifest to meet diagnostic criteria?

<p>Prior to age 12 (D)</p> Signup and view all the answers

What is considered the best predictor of outcomes for individuals with ASD?

<p>IQ (B)</p> Signup and view all the answers

Which of the following statements about savant syndrome is true?

<p>It entails having rare special talents or abilities. (A)</p> Signup and view all the answers

Which of the following biological factors is most clearly associated with Autism Spectrum Disorder?

<p>Polygenic disorder evidence (B)</p> Signup and view all the answers

What type of medication is primarily used to reduce obsessive or repetitive behaviors in individuals with ASD?

<p>Atypical antipsychotic medications (B)</p> Signup and view all the answers

What aspect of cognitive functioning is NOT typically assessed in intellectual developmental disorder?

<p>Non-verbal communication (C)</p> Signup and view all the answers

What neurological characteristic is often observed in individuals with Autism Spectrum Disorder?

<p>Greater brain and head size (D)</p> Signup and view all the answers

Which of the following distinguishes bulimia nervosa from anorexia nervosa in terms of interpersonal concerns?

<p>Bulimia nervosa is associated with a greater focus on attractiveness and relationships. (A)</p> Signup and view all the answers

What is a common physiological factor linked to the development of eating disorders?

<p>Lower functioning of the hypothalamus. (D)</p> Signup and view all the answers

Which symptom is specifically associated with binge eating disorder and not found in anorexia or bulimia?

<p>Marked distress regarding binge eating. (B)</p> Signup and view all the answers

What psychological element is emphasized by Hilde Bruch's psychodynamic view on eating disorders?

<p>Disturbed mother-child interactions causing ego deficiencies. (A)</p> Signup and view all the answers

In binge eating disorder, how often must binge eating episodes occur to meet diagnostic criteria?

<p>At least once a week for 3 months. (B)</p> Signup and view all the answers

Which of the following is NOT considered a treatment strategy for intellectual developmental disorder (IDD)?

<p>Electroconvulsive therapy (B)</p> Signup and view all the answers

What is the primary method for assessing severity of intellectual developmental disorder according to DSM-5-TR?

<p>Adaptive functioning level (B)</p> Signup and view all the answers

Which cognitive deficit involves the inability to recognize objects or people?

<p>Agnosia (C)</p> Signup and view all the answers

Which of the following genetic conditions is associated with an increased risk for Alzheimer's disease?

<p>Trisomy 21 (C)</p> Signup and view all the answers

Which environmental factor is associated with learning and communication disorders?

<p>Lead poisoning (D)</p> Signup and view all the answers

What type of disorder is characterized by a significant cognitive decline due to a vascular event?

<p>Vascular neuro-cognitive disorder (C)</p> Signup and view all the answers

Which treatment is commonly used to manage agitation in individuals with neuro-cognitive disorders?

<p>Antipsychotics (B)</p> Signup and view all the answers

Which of the following symptoms is NOT typically associated with delirium?

<p>Persistent hallucinations (A)</p> Signup and view all the answers

Which of the following symptoms distinguishes oppositional defiant disorder (ODD) from conduct disorder (CD)?

<p>Argumentative and defiant behavior (D)</p> Signup and view all the answers

What genetic factor is associated with an increased risk of developing aggressive traits and conduct disorder?

<p>MAOA gene variant (B)</p> Signup and view all the answers

Which statement correctly describes the prevalence of conduct disorder relative to gender?

<p>More common in boys than girls (A)</p> Signup and view all the answers

What is the primary goal of cognitive-behavioral therapy for children with conduct disorder and oppositional defiant disorder?

<p>To change the way children interpret interpersonal situations (C)</p> Signup and view all the answers

According to Cleckley’s criteria, which of the following traits is a hallmark of psychopathy?

<p>Pathological egocentricity (D)</p> Signup and view all the answers

Which statement reflects a misconception about antisocial personality disorder (ASPD)?

<p>ASPD is a rare disorder. (C)</p> Signup and view all the answers

Which environmental factor contributes significantly to the development of conduct disorder?

<p>Physical abuse or severe neglect in childhood (B)</p> Signup and view all the answers

What treatment approach is typically least effective for individuals diagnosed with antisocial personality disorder?

<p>Traditional talk therapy focused on self-reflection (C)</p> Signup and view all the answers

Which characteristic traits often correlate with antisocial personality disorder (ASPD) in terms of biological influence?

<p>Decreased frontal lobe activity and low levels of fear (B)</p> Signup and view all the answers

How does relational aggression primarily manifest, particularly among girls?

<p>Slander, rumor-starting, and friendship manipulation (B)</p> Signup and view all the answers

What is required for a diagnosis of intermittent explosive disorder?

<p>Episodes of aggression out of proportion to a situation (C)</p> Signup and view all the answers

Which of the following best describes the 'restricting type' of anorexia nervosa?

<p>Severe calorie restriction with eventual loss of interest in food (C)</p> Signup and view all the answers

What defines the binge-eating episode in bulimia nervosa?

<p>Eating a significantly larger amount of food than most would in similar circumstances (C)</p> Signup and view all the answers

Which factor is NOT commonly associated with the development of intermittent explosive disorder?

<p>Dietary habits (D)</p> Signup and view all the answers

What is the minimal BMI for a diagnosis of mild anorexia nervosa?

<p>17 kg/m² (C)</p> Signup and view all the answers

What characterizes ARFID (Avoidant/Restrictive Food Intake Disorder)?

<p>Persistent failure to meet energy needs due to minimal interest in food (C)</p> Signup and view all the answers

What distinguishes the binge-eating/purging type of anorexia nervosa from the restricting type?

<p>Engagement in purging behaviors following binge eating (C)</p> Signup and view all the answers

Between which ages does anorexia nervosa typically begin?

<p>14 and 18 (D)</p> Signup and view all the answers

What is a common consequence of intermittent explosive disorder?

<p>Legal difficulties (A)</p> Signup and view all the answers

What is the lifetime prevalence of developing anorexia nervosa in the general population?

<p>1% (B)</p> Signup and view all the answers

Flashcards

What are the 3 presentations of ADHD?

ADHD can manifest in three ways: predominantly inattentive, predominantly hyperactive-impulsive, or combined presentation.

What is the age limit for ADHD symptom onset?

For a diagnosis of ADHD, symptoms must be present before the age of 12 years.

What are the two main areas of deficits in ASD?

ASD is characterized by persistent deficits in both social communication and social interaction, and restricted, repetitive patterns of behavior, interests, or activities.

What are the two key features of ASD?

Individuals with ASD exhibit persistent deficits in social communication and social interaction, and restricted, repetitive patterns of behavior, interests, or activities.

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What are the 3 types of ADHD drugs?

Stimulants like Ritalin, Dexedrine, Concerta, Adderall, and Vyvanse increase dopamine levels. Other medication options include non-stimulants (Intuniv, Qelbree) that regulate norepinephrine.

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Savant Syndrome

A rare condition where individuals with ASD possess exceptional abilities in specific areas. These talents can be highly specialized, such as extraordinary memory, artistic skills, or mathematical calculations.

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Polygenic Disorder

A condition caused by multiple genes working together. In ASD, family and twin studies suggest that many genes contribute to its development.

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Mirror Neuron Deficits

Difficulties with understanding and responding to emotions or intentions of others. Individuals with ASD may struggle with 'reading' social cues and empathizing with others.

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Intellectual Developmental Disorder

A condition characterized by limitations in intellectual functioning and adaptive behavior, impacting an individual's ability to learn, solve problems, and manage daily life.

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Adaptive Functioning

Skills needed to meet life's demands, including personal independence, social responsibility, and managing everyday activities.

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SSRIs for ASD

Selective Serotonin Reuptake Inhibitors (SSRIs) are medications used to reduce anxiety, repetitive behaviors, and aggression in individuals with ASD.

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What's the main difference between anorexia and bulimia?

People with bulimia are more concerned about pleasing others, being attractive, and having relationships, while people with anorexia focus on themselves and their own body image.

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What are some biological factors that can contribute to eating disorders?

Genetic factors, hormonal changes during puberty (especially in girls), imbalances in neurochemicals like serotonin, and dysfunction in areas like the hypothalamus can all play a role.

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Explain Hilde Bruch's psychodynamic view of eating disorders.

Bruch believed that poor mother-child interaction leads to ego deficiencies and perceptual disturbances in children, making them vulnerable to developing eating disorders.

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What are some cognitive factors associated with eating disorders?

These include obsessive thoughts, perfectionism, dissociation, impaired cognitive style, and cognitive biases. Individuals may also struggle with low self-esteem, a need to please others, and all-or-nothing thinking.

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What are some psychosocial factors related to eating disorders?

People with eating disorders often have difficulty regulating emotions and may use disordered eating as a maladaptive coping strategy to deal with difficult feelings.

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Intellectual Developmental Disorder (IDD)

A neurodevelopmental disorder characterized by impairments in intellectual functioning and adaptive behaviors, starting in the developmental period. It is characterized by both intellectual and adaptive deficits.

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Down Syndrome

A genetic disorder caused by an extra copy of chromosome 21. It is a common cause of intellectual developmental disorder.

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Fetal Alcohol Syndrome

A condition caused by prenatal exposure to alcohol. It can lead to intellectual developmental disorder and a range of physical and behavioral problems.

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Mainstreaming

A strategy used in education that integrates children with disabilities into regular classrooms.

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Tourette's Disorder

A neurodevelopmental disorder characterized by motor and vocal tics. These tics are involuntary movements or vocalizations that occur repeatedly.

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Individualized Education Plan (IEP)

A document that outlines a child's specific educational needs and goals, including individualized interventions tailored to their specific learning disabilities.

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Alzheimer's Disease

A progressive neurodegenerative disorder leading to dementia. It is characterized by memory loss, confusion, and behavioral changes. It affects the brain's ability to learn and remember.

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Neurofibrillary Tangles

Twisted strands of protein called tau that accumulate inside neurons, disrupting their function. They're found in Alzheimer's.

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Overt-Destructive Behavior

Behavior that involves obvious damage or destruction of property or physical harm to others.

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Covert-Nondestructive Behavior

Behavior that involves indirect or subtle actions that violate social norms but do not involve physical harm or property damage.

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Relational Aggression

A form of aggression that aims to damage social relationships, often through manipulation, rumors, or social exclusion.

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Oppositional Defiant Disorder (ODD)

A disorder characterized by a persistent pattern of angry, defiant, and irritable behavior, often directed towards authority figures.

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Conduct Disorder (CD)

A disorder characterized by a persistent pattern of violating social norms and the rights of others, often involving aggression, deceit, and property destruction.

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MAOA Gene Variant

A genetic variation linked to increased risk of aggression and conduct disorder, particularly when combined with childhood maltreatment.

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Prefrontal Cortex Function in CD

Individuals with conduct disorder often show abnormal functioning in the prefrontal cortex, which is responsible for planning, impulse control, and decision-making.

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Cognitive Behavioral Therapy (CBT) for CD/ODD

A type of therapy that aims to change negative thought patterns and behaviors associated with conduct disorder and oppositional defiant disorder.

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Antisocial Personality Disorder (ASPD)

A personality disorder characterized by a pervasive pattern of disregard for and violation of the rights of others.

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Low-Fear Hypothesis in ASPD

The theory that individuals with antisocial personality disorder have a reduced capacity for fear and anxiety, which may contribute to their reckless and impulsive behavior.

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Intermittent Explosive Disorder (IED)

A disorder characterized by frequent, impulsive, and severe acts of aggression, often verbally or physically, that are out of proportion to the situation. Typically diagnosed in individuals aged 6 or older.

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IED: Causes

The exact cause of IED is unknown, but it is thought to involve an imbalance in serotonin levels and may be linked to genetic factors and environmental influences, including parenting.

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IED: Consequences

IED can lead to significant difficulties in a person's life, including legal issues, relationship problems, and job loss.

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Anorexia Nervosa

An eating disorder characterized by severe restriction of food intake leading to significantly low body weight, intense fear of gaining weight, and a distorted body image.

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Anorexia Nervosa: Types

Anorexia nervosa has two main types: restricting and binge-eating/purging. The restricting type involves strict food restriction, while the binge-eating/purging type includes episodes of binge eating followed by purging behaviors like vomiting.

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Bulimia Nervosa

An eating disorder marked by recurrent episodes of binge eating, followed by compensatory behaviors like vomiting, excessive exercise, or misuse of laxatives to prevent weight gain.

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Bulimia Nervosa: Characteristics

Bulimia nervosa includes a sense of lack of control during binge eating, self-evaluation heavily influenced by body shape and weight, and inappropriate compensatory behaviors happening at least once a week for 3 months.

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Pica

An eating disorder characterized by persistent eating of non-nutritive, non-food substances, like dirt, paper, or hair, for at least one month, which is inappropriate for the individual's developmental level.

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Rumination Disorder

An eating disorder involving the repeated regurgitation of food, often without discomfort, for at least one month, not due to a medical condition.

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Avoidant/Restrictive Food Intake Disorder (ARFID)

An eating or feeding disorder where individuals avoid or restrict food based on sensory characteristics (taste, smell, texture) or due to concerns about potential negative consequences, leading to significant nutritional deficiencies.

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Study Notes

Neurodevelopmental Disorders

  • ADHD (diagnosed in adulthood too): symptoms (inattention or hyperactivity/impulsivity) present before age 12, and in 2+ settings. Presentations include predominantly inattentive, predominantly hyperactive-impulsive, and combined.
  • ASD (autism): persistent deficits in social communication and social interaction across multiple contexts, including social-emotional reciprocity, nonverbal communication, and relationship development; restricted, repetitive patterns of behavior, interests, or activities.
  • Intellectual Developmental Disorder (IDD): deficits in intellectual function (reasoning, problem-solving, learning) and adaptive functioning (personal independence and social responsibility), confirmed by clinical assessment and standardized tests; onset during developmental period. Severity rated as mild, moderate, severe, profound.
  • Learning, Communication, and Motor Disorders: deficits or abnormalities in specific skills or behaviors not due to intellectual disability, global developmental delay, neurological disorders, or general external factors.

ADHD (cont.)

  • DSM-5-TR (Inattention): Fails to give close attention, sustaining attention, listen, follow instructions, organize tasks, avoid mental tasks, lose things, easily distracted, forgetful.
  • DSM-5-TR (Hyperactivity): Fidgeting, leaving seat, running/climbing inappropriately, inability to play quietly, “on the go,” talks excessively, blurts out answers, difficulty waiting, interrupting.
  • Epidemiology: Affects 5-7% of children, boys > girls, multiple settings, outcomes vary. Adults: ~4.4% diagnosed.
  • Etiology (Biological): Cerebral cortex size, prefrontal cortex immaturity, neurotransmitter dysregulation (dopamine and norepinephrine). Prenatal and birth complications.
  • Etiology (Psychosocial): Frequent life disruptions (moving, divorce), father's increased risk for antisocial behavior, hostile or conflicted parent-child interactions.
  • Treatments: Drug therapy (stimulants like Ritalin, Dexedrine, Concerta, Adderall, Vyvanse; increasing dopamine; non-stimulants (Intuniv, Qelbree), behavioral therapy (reinforcing attentive behaviors, extinguishing impulsive ones).

ASD (cont.)

  • Epidemiology: ~50% with intellectual disability; IQ best predictor of outcome; savant syndrome (rare); early childhood onset required; ongoing support may be needed in adulthood.
  • Etiology (Biological): Polygenic disorder; general vulnerability to cognitive impairment; neurological factors (brain/head size, seizures in 30%), brain structure abnormalities, genetics/prenatal/birth complications. Serotonin and dopamine implicated.
  • Etiology (Psychological factors): Difficulty relating to others' feelings (theory of mind, mirror neuron dysfunction); lack of empathy.
  • Treatments: Drug treatments (SSRIs (reduce repetitive behaviors), atypical antipsychotics (reduce obsessive behaviors), stimulants (improve attention)); psychosocial treatments (behavioral techniques, structured education, operant conditioning, comprehensive behavior therapy).

IDD (cont.)

  • Etiology (Genetic): Phenylketonuria (PKU), Tay-Sachs disease, Trisomy 21 (Down syndrome), Fragile X syndrome.
  • Etiology (Prenatal): Infections (rubella, syphilis), drugs/alcohol (fetal alcohol syndrome).
  • Treatments: Behavioral strategies (operant conditioning, modeling); drug therapy (antipsychotics, antidepressants); social programs (mainstreaming, group homes).

Learning, Communication, and Motor Disorders

  • Causes (Learning/Communication): Genetic factors, brain structure/functioning abnormalities (e.g., Broca's area), environmental factors (lead poisoning, birth defects, sensory deprivation, low SES).
  • Treatments: Therapies to build skills; individualized education plans (IEP), parent/teacher interventions, changes in skills affecting brain function.
  • Motor Disorders: Tourette's disorder.

Neurocognitive Disorders (NCDs)

  • Major NCD: Dementia (like Alzheimer's), vascular NCD, NCDs associated with other medical conditions.
  • Cognitive Deficits: Amnesia, aphasia, echolalia, palilalia, apraxia, agnosia, loss of executive function.
  • Dementia (Alzheimer's): Clear decline in learning and memory, progressing to profound loss and disorientation; common psychiatric symptoms (agitation, irritability, apathy, dysphoria, hallucinations/delusions).
  • Biology of Alzheimer's: Neurofibrillary tangles (tau protein), senile plaques (beta-amyloid), extensive cell death (cortex shrinks, ventricles enlarge).
  • Causes of Alzheimer's: Genetic predisposition (ApoE gene), chromosome 21 (Down syndrome), multiple neurotransmitter deficits (acetylcholine, norepinephrine, serotonin, somatostatin, peptide Y).
  • Vascular NCD: Significant decline in processing speed, attention, and executive functions due to cerebrovascular disease or stroke.

Delirium

  • Causes: Neurotransmitter abnormalities, prior neurocognitive disorder, intoxication/withdrawal, electrolyte/medication imbalances, toxic substances, medical conditions affecting acetylcholine levels.
  • Treatments: Treat underlying condition, discontinue contributing drugs, antipsychotic medications, nursing care, secure atmosphere.

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Explore the key aspects of neurodevelopmental disorders, including ADHD, autism spectrum disorder (ASD), and intellectual developmental disorder (IDD). This quiz covers symptoms, presentations, and classifications of these disorders, providing a comprehensive understanding for better recognition and assessment.

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