Myasthenia Gravis (MG) Diagnosis: Physical Examination

To detect muscle weakness, particularly in the early stages of MG.

It indicates ocular MG, which guides further testing for an accurate diagnosis.

Reduced activity of acetylcholinesterase, leading to an increase in available acetylcholine.

<p>An improvement in eyelid drooping of at least 2 millimeters after the ice pack is removed.</p> Signup and view all the answers

<p>It is cheap, safe, and quick to perform, taking approximately 3-5 minutes.</p> Signup and view all the answers

<p>Because the cold temperature is thought to improve neuromuscular transmission in MG patients, specifically those with ptosis.</p> Signup and view all the answers

<p>Drooping eyelids (ptosis) = Ocular MG Difficulty swallowing (dysphagia) = Generalized MG Facial muscle weakness affecting expressions = Generalized MG Weakness in limbs = Generalized MG</p> Signup and view all the answers

<p>Physical examination = Diagnosis of Ocular MG Ice pack test = Detection of weakness in limbs</p> Signup and view all the answers

<p>Reduced activity of acetylcholinesterase = Improving neuromuscular transmission Increased availability of acetylcholine = Improving muscle movement Increased activity of acetylcholinesterase = Worsening neuromuscular transmission Decreased availability of acetylcholine = Reducing muscle movement</p> Signup and view all the answers

<p>Improvement in eyelid drooping of at least 2 millimeters = Positive test result No change in eyelid drooping = Negative test result Worsening of eyelid drooping = Inconclusive test result No test result = Invalid test</p> Signup and view all the answers

<p>Quick to perform = Ice pack test Ability to observe muscle weakness = Physical examination Ability to detect weakness in limbs = Physical examination Cheap and safe = Ice pack test</p> Signup and view all the answers

<p>Physical examination = Only used for patients with generalized MG Ice pack test = Cannot determine MG type</p> Signup and view all the answers