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Questions and Answers
What is associated with the presence of follicles in meninges?
What is associated with the presence of follicles in meninges?
What breaks microglia tolerance, according to van der Poel et al.?
What breaks microglia tolerance, according to van der Poel et al.?
In PPMS autopsies, what type of demyelination is more common in cortical lesions compared to white matter?
In PPMS autopsies, what type of demyelination is more common in cortical lesions compared to white matter?
What correlates with the perivascular enrichment of CD4+ T cells?
What correlates with the perivascular enrichment of CD4+ T cells?
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What is affected by the working model of parenchymal tissue damage?
What is affected by the working model of parenchymal tissue damage?
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What is the name of the genetic variant associated with a 5-fold increased risk of developing multiple sclerosis?
What is the name of the genetic variant associated with a 5-fold increased risk of developing multiple sclerosis?
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Which of the following immune cells is expanded, activated, and associated with multiple sclerosis lesions?
Which of the following immune cells is expanded, activated, and associated with multiple sclerosis lesions?
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What is the effect of disease-modifying therapies on the sequence of events in lymph nodes?
What is the effect of disease-modifying therapies on the sequence of events in lymph nodes?
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What is the name of the molecules found in cervical lymph nodes that are specific to the brain?
What is the name of the molecules found in cervical lymph nodes that are specific to the brain?
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Which of the following is a characteristic of circulating T cell subsets in multiple sclerosis?
Which of the following is a characteristic of circulating T cell subsets in multiple sclerosis?
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What is the role of meningeal lymphatic vessels in the initiation of the detrimental immune response in multiple sclerosis?
What is the role of meningeal lymphatic vessels in the initiation of the detrimental immune response in multiple sclerosis?
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What percentage of patients display grey matter lesions?
What percentage of patients display grey matter lesions?
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Which type of cells are responsible for 41% of lesions in MS patients?
Which type of cells are responsible for 41% of lesions in MS patients?
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What is associated with meningeal inflammation in MS?
What is associated with meningeal inflammation in MS?
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Which B cell subset is associated with CD4+ TRM cells in MS lesions?
Which B cell subset is associated with CD4+ TRM cells in MS lesions?
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What is the median disease duration to autopsy in MS patients?
What is the median disease duration to autopsy in MS patients?
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What type of immune cells are activated in MS and cross the inflamed endothelium?
What type of immune cells are activated in MS and cross the inflamed endothelium?
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