Morphological Abnormalities of Neutrophils

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10 Questions

What is the characteristic of Ewingii species?

Infecting neutrophils

What is the primary component of the inclusions in May-Hegglin anomaly?

Myosin heavy chains

What is the characteristic of giant platelets in certain disorders?

They are larger than normal platelets

What is the primary anomaly in Chédiak-Higashi syndrome?

Lysosomal membrane defect

What is the characteristic of neutrophils in Chédiak-Higashi syndrome?

Impaired chemotaxis and delayed killing of ingested bacteria

What is the characteristic of Alder-Reilly anomaly?

Large purple-red granules in cells of the myeloid and lymphocytic series

What is the composition of the dense granules in Alder-Reilly anomaly?

Precipitated or partially digested mucopolysaccharides

What is the effect of Alder-Reilly anomaly on leukocyte function?

Leukocyte function is not affected

What is the characteristic of granulopoietic alterations?

Qualitative disorders

What is the characteristic of defective PMNs in Chédiak-Higashi syndrome?

Not efficient bactericidal cells

Test your knowledge of neutrophil abnormalities, including toxic vacuolization and hypersegmentation, which can be associated with megaloblastic anemia and infections. Identify the different types of nuclear abnormalities and their causes. Improve your understanding of hematological disorders.

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